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dc.contributor.authorWong, Aaron K.
dc.contributor.authorPark, Christopher Y.
dc.contributor.authorGreene, Casey S.
dc.contributor.authorBongo, Lars Ailo
dc.contributor.authorGuan, Yuanfang
dc.contributor.authorTroyanskaya, Olga
dc.date.accessioned2013-03-13T07:27:32Z
dc.date.available2013-03-13T07:27:32Z
dc.date.issued2012
dc.description.abstractIntegrative multi-species prediction (IMP) is an interactive web server that enables molecular biologists to interpret experimental results and to generate hypotheses in the context of a large cross-organism compendium of functional predictions and networks. The system provides a framework for biologists to analyze their candidate gene sets in the context of functional networks, as they expand or focus these sets by mining functional relationships predicted from integrated high-throughput data. IMP integrates prior knowledge and data collections from multiple organisms in its analyses. Through flexible and interactive visualizations, researchers can compare functional contexts and interpret the behavior of their gene sets across organisms. Additionally, IMP identifies homologs with conserved functional roles for knowledge transfer, allowing for accurate function predictions even for biological processes that have very few experimental annotations in a given organism. IMP currently supports seven organisms (Homo sapiens, Mus musculus, Rattus novegicus, Drosophila melanogaster, Danio rerio, Caenorhabditis elegans and Saccharomyces cerevisiae), does not require any registration or installation and is freely available for use at http://imp.princeton.edu.en
dc.identifier.citationNucleic Acids Research 40(2012) nr. W1 s. W484-W490en
dc.identifier.issn0305-1048
dc.identifier.otherFRIDAID 964132
dc.identifier.otherhttp://dx.doi.org/10.1093/nar/gks458
dc.identifier.urihttp://hdl.handle.net/10037/4962
dc.identifier.urnURN:NBN:no-uit_munin_4690
dc.language.isoengen
dc.publisherOxford University Pressen
dc.rights.accessRightsopenAccess
dc.subjectVDP::Mathematics and natural science: 400::Information and communication science: 420::Simulation, visualization, signal processing, image processing: 429en
dc.subjectVDP::Matematikk og Naturvitenskap: 400::Informasjons- og kommunikasjonsvitenskap: 420::Simulering, visualisering, signalbehandling, bildeanalyse: 429en
dc.subjectVDP::Mathematics and natural science: 400::Information and communication science: 420::Knowledge based systems: 425en
dc.subjectVDP::Matematikk og Naturvitenskap: 400::Informasjons- og kommunikasjonsvitenskap: 420::Kunnskapsbaserte systemer: 425en
dc.subjectVDP::Mathematics and natural science: 400::Basic biosciences: 470::Genetics and genomics: 474en
dc.subjectVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470::Genetikk og genomikk: 474en
dc.titleIMP: a multi-species functional genomics portal for integration, visualization and prediction of protein functions and networksen
dc.typeJournal articleen
dc.typeTidsskriftartikkelen
dc.typePeer revieweden


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