• Circadian clock mechanism driving mammalian photoperiodism 

      Wood, Shona Hiedi; Hindle, Matthew; Mizoro, Yasutaka; Cheng, Y; Saer, Ben; Miedzinska, K; Christian, Helen; Begley, Nicola; McNeilly, Judy; McNeilly, Alan; Meddle, Simone; Burt, Dave; Loudon, Andrew S.I. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-27)
      The annual photoperiod cycle provides the critical environmental cue synchronizing rhythms of life in seasonal habitats. In 1936, Bünning proposed a circadian-based coincidence timer for photoperiodic synchronization in plants. Formal studies support the universality of this so-called coincidence timer, but we lack understanding of the mechanisms involved. Here we show in mammals that long photoperiods ...