Mx proteins are antiviral GTPases, which are induced by type I IFN and virus infection. Analysis of the Atlantic salmon genome revealed the presence of 9 Mx genes localized to three chromosomes. A cluster of three Mx genes (SsaMx1 – SsaMx3), which includes previously cloned Mx genes, is present on chromosome (Chr) 12. A cluster of five Mx genes (SsaMx4-SsaMx8) is present on Chr25 while one Mx gene ...

The tuna fishery is an important sector in Ghana. In 2009, total landing of tuna in Ghana represented about 24% of total catches in the East Atlantic. Canned tuna is Ghana’s most important non-traditional export commodity in terms of foreign exchange earnings. The main focus of this thesis is to analyze the performance of Ghanaian canned tuna export to the EU -27 market. Performance is measured in ...

The scavenger endothelial cells (SECs) of vertebrates are an important class of endocytic cells responsible for clearance of foreign and physiological waste macromolecules, partitioning in the immune system, functioning as a cellular powerplant by producing high energy metabolites like lactate and acetate. All animal phyla possess SECs, but the tissue localization of SECs has only been investigated ...

Two bacterial isolates from the Barents Sea, both belonging to the genus <i>Algibacter</i>, were found to yield extracts with anti-bacterial bioactivity. Mass spectrometry guided dereplication and purification of the active extracts lead to the isolation of the same active principle in both extracts. The structure of the bioactive compound was identified via mass spectrometry and nuclear resonance ...

Bacterial resistance against antibiotic treatment has become a major threat to public health. Antimicrobial peptides (AMPs) have emerged as promising alternative agents for treatment of infectious diseases. This study characterizes novel synthetic peptides sequentially derived from the AMP centrocin 1, isolated from the green sea urchin, for their applicability as anti-infective agents.The microbicidal ...

Infections due to pathogens impact global aquaculture economy, where diseases caused by bacteria should be in particular focus due to antibiotic resistance. Hepcidin and NK-lysin are important innate immune factors having potential to be exploited as alternatives to antibiotics due to their antimicrobial activity and immunomodulatory capacity. In this study, the recombinant proteins of hepcidin 2 ...

Det ble i denne oppgaven gjennomført en undersøkelse for antibakteriell aktivitet i ulike vev og organer i vanlig uer (Sebastes marinus). Totalt ble 11 forskjellige organer undersøkt for antibakteriell aktivitet mot Escherichia coli, Pesudomonas aeruginosa, Cornyebacterium glutamicum og Staphylococcus aureus. Frysetørkede prøver ble ekstrahert med 60% (v/v) acetonitril tilsatt 0,1% trifluoreddiksyre. ...

Natural transformation is one of three mechanisms by which genetic material can be exchanged horizontally between bacteria and the only mechanism that the DNA is actively taken up by the recipient cell. It is also one of the mechanism by which bacteria acquire resistance against antibiotics and thus creating a growing concern worldwide for aquaculture industries. This study uses Acinetobacter baylyi ...

An enduring challenge in the vaccinology of infectious pancreatic necrosis virus (IPNV) is the lack of correlation between neutralizing antibodies and protection against mortality. To better understand the immunological basis of vaccine protection, an efficacy trial including Atlantic salmon (Salmo salar L.) vaccinated with a high antigen (HiAg) or low antigen (LoAg) dose vaccine was carried out ...