• Discovery and structural assignment of (S)-sydosine from amphipod-derived Aspergillus sydowii MBC15-11F through HRMS, advanced Mosher, and molecular modelling analyses 

      Qader, Mallique; Mweetwa, Larry L; Rämä, Teppo; Thissera, Bathini; Milne, Bruce F; Abdelmohsen, Usama R; Orfali, Raha; Tawfike, Ahmed; Esheli, Manal; Oluwabusola, Emmanuel T; Jaysainghe, Lalith; Jaspars, Marcel; Rateb, Mostafa E (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-21)
      Aims - This study aims to prioritize fungal strains recovered from under-explored habitats that produce new metabolites. HRMS dereplication is used to avoid structure redundancy, and molecular modelling is used to assign absolute configuration.<p> <p>Methods and results - MBC15-11F was isolated from an amphipod and identified using ITS, 28S, and β-tubulin phylogeny as Aspergillus sydowii. Chemical ...