Blar i forfatter Universitetsbiblioteket "Åsheim, June"

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    • Platelet and mitochondrial RNA is decreased in plasma-derived extracellular vesicles in women with preeclampsia—an exploratory study 

      Lekva, Tove; Sundaram, Arvind; Roland, Marie Cecilie; Åsheim, June; Michelsen, Annika Elisabet; Norwitz, Errol R.; Aukrust, Pål; Gilfillan, Gregor; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-23)
      Background - Circulating extracellular vesicles (EVs) are increased in preeclampsia (PE) and are associated with severity and progression. We examined in this exploratory cohort study if the mRNAs and long noncoding RNAs (lncRNAs) in plasma-derived EVs were dysregulated in PE compared to normal pregnancy and display different temporal patterns during gestation.<p> <p>Methods - We isolated EVs ...