Rainsford, Philip Ben; Sarre, Birta R.; Falavigna, Margherita; Brandsdal, Bjørn Olav; Flaten, Gøril Eide; Jakubec, Martin; Isaksson, Johan Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-22)
Water/Ion NMR Detected – Phospholipid Vesicle Permeability Assay (WIND-PVPA), is presented as a novel,
straightforward and automatable method to assess lipid barrier integrity in vitro. The apparent permeability
constants of water- and ions across the PVPA barriers are determined in a one-pot experiment under the influence
of membrane-active guest molecules. NMR spectroscopy is used to quantify ...