Blar i forfatter Universitetsbiblioteket "Pucelik, Barbara"

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    • DYRK1A kinase inhibitors promote β-cell survival and insulin homeostasis 

      Barzowska, Agata; Pucelik, Barbara; Pustelny, Katarzyna; Matsuda, Alex; Martyniak, Alicja; Stępniewski, Jacek; Maksymiuk, Anna; Dawidowski, Maciej; Rothweiler, Ulli; Dulak, Józef; Dubin, Grzegorz; Czarna, Anna (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-31)
      The rising prevalence of diabetes is threatening global health. It is known not only for the occurrence of severe complications but also for the SARS-Cov-2 pandemic, which shows that it exacerbates susceptibility to infections. Current therapies focus on artificially maintaining insulin homeostasis, and a durable cure has not yet been achieved. We demonstrate that our set of small molecule ...