Browsing Universitetsbiblioteket by Author "Tveita, Anders Aune"

Now showing items 1-3 of 3

    • B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells 

      Huszthy, Peter Csaba; Gopalakrishnan, Ramakrishna Prabhu; Jacobsen, Johanne Tracey; Haabeth, Ole Audun; Løset, Geir Åge; Braathen, Ranveig; Schenck, Karl; Tveita, Anders Aune; Munthe, Ludvig Andre; Bogen, Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-03)
      The B cell receptors (BCRs) for antigen express variable (V) regions that are enormously diverse, thus serving as markers on individual B cells. V region-derived idiotypic (Id) peptides can be displayed as pId:MHCII complexes on B cells for recognition by CD4<sup>+</sup> T cells. It is not known if naive B cells spontaneously display pId:MHCII in vivo or if BCR ligation is required for expression, ...

    • Markers of cellular senescence is associated with persistent pulmonary pathology after COVID-19 infection 

      Lekva, Tove; Ueland, Thor; Halvorsen, Bente; Murphy, Sarah Louise Mikalsen; Dyrhol-Riise, Anne Ma; Tveita, Anders Aune; Finbråten, Ane-Kristine; Mathiessen, Alexander; Muller, Karl Erik; Aaløkken, Trond Mogens; Skjønsberg, Ole Henning; Lerum, Tøri Vigeland; Aukrust, Pål; Dahl, Tuva Børresdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-19)
      Background: The lungs are the organ most likely to sustain serious injury from coronavirus disease 2019 (COVID-19). However, the mechanisms for long-term complications are not clear. Patients with severe COVID-19 have shorter telomere lengths and higher levels of cellular senescence, and we hypothesized that circulating levels of the telomere-associated senescence markers chitotriosidase, ...

    • Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies 

      Trøseid, Marius; Dahl, Tuva Børresdatter; Holter, Jan Cato; Kildal, Anders Benjamin; Murphy, Sarah Louise Mikalsen; Yang, Kuan; Quiles Jimenez, Ana Maria Teresa; Heggelund, Lars; Muller, Karl Erik; Tveita, Anders Aune; Michelsen, Annika Elisabet; Bøe, Simen; Holten, Aleksander Rygh; Hoel, Hedda Benedicte; Mathiessen, Alexander; Aaløkken, Trond Mogens; Fevang, Børre; Granerud, Beathe Kiland; Tonby, Kristian; Nezvalova-Henriksen, Katerina; Lerum, Tøri Vigeland; Müller, Fredrik; Skjønsberg, Ole Henning; Barratt-Due, Andreas; Riise, Anne Margarita Dyrhol; Aukrust, Pål; Halvorsen, Bente Evy; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-18)
      Background - T-cell activation is associated with an adverse outcome in COVID-19, but whether T-cell activation and exhaustion relate to persistent respiratory dysfunction and death is unknown.<p> <p>Objectives - To investigate whether T-cell activation and exhaustion persist and are associated with prolonged respiratory dysfunction and death after hospitalization for COVID-19.<p> <p>Methods ...