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Barriers to and facilitators for making emergency calls – a qualitative interview study of stroke patients and witnesses
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-26)Background and objectives - Early access to hospital for diagnosis and treatment is strongly recommended for patients with acute stroke. Unfortunately, prehospital delay frequently occurs. The aim of the current study was to gain in-depth insight into patient experience and behavior in the prehospital phase of a stroke.<p> <p>Methods - We conducted qualitative interviews with a purposive sample ... -
The elusive impact of L2 immersion on translation priming. Studies in Second Language Acquisition
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-18)A growing consensus sees the bilingual lexicon as an integrated, nonselective system. However, the way bilingual experience shapes the architecture and functioning of the lexicon is not well understood. This study investigates bilingual lexical-semantic representation and processing employing written translation priming. We focus on the role of active exposure to and use of the second language ... -
Pilot-RCT Finds No Evidence for Modulation of Neuronal Networks of Auditory Hallucinations by Transcranial Direct Current Stimulation
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-12)Background: Transcranial direct current stimulation (tDCS) is used as treatment for auditory verbal hallucinations (AVH). The theory behind the treatment is that tDCS increases activity in prefrontal cognitive control areas, which are assumed to be hypoactive, and simultaneously decreases activity in temporal speech perception areas, which are assumed to be hyperactive during AVH. We tested this ... -
Modelling drug diffusion through unstirred water layers allows real-time quantification of free/loaded drug fractions and release kinetics from colloidal-based formulations
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-25)The correlation between in vivo and in vitro data is yet not sufficiently optimized to allow a significant reduction and replacement of animal testing in pharmaceutical development. One of the main reasons for this lies in the poor mechanistic understanding and interpretation of the physical mechanisms enabling formulation rely on for deploying the drug. One mechanism that still lacks a proper ... -
Economic analyses of supported employment programmes for people with mental health conditions: A systematic review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-19)Background - Employment is intrinsic to recovery from mental health conditions, helping people live independently. Systematic reviews indicate supported employment (SE) focused on competitive employment, including individual placement and support (IPS), is effective in helping people with mental health conditions into work. Evidence is limited on cost-effectiveness. We comprehensively reviewed ... -
Facilitating Participation for Youths in Child Welfare Services in Transition to Adulthood: Practice between Formalities and Empowerment
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-21)This article examines social workers’ perceptions of youths’ participation and how their perceptions influence their practice towards youths in aftercare. The article is based on qualitative interviews with 38 social workers in child welfare services (CWS) and collaborative welfare services. The interviews were analysed using a hermeneutic approach. We identified two practices with different objectives: ... -
ILSAs in Aesthetics in school – which competences develops through drama in learning processes
(Chapter; Bokkapittel, 2022-09-22)This chapter discusses the role of aesthetic education with a focus on educational drama and theatre. It investigates the lack of international large-scale studies (ILSA) in the field of aesthetic education and exemplifies how to measure competence development in one of the aesthetic subjects: drama, based on the international mixed method large-scale assessment study DICE (Drama Improves Lisbon Key ... -
Feil i aldersvurderingen av unge asylsøkere
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-08)Dagens bruk av verktøyet BioAlder for å finne sannsynlig aldersspenn hos asylsøkere er basert på en statistisk feilslutning. Mindreårige risikerer å klassifiseres som voksne. -
Genotyping av pasienter behandlet med selektive serotoninreopptakshemmere
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-26)BAKGRUNN - Selektive serotoninreopptakshemmere (SSRI) brukes av over 180 000 mennesker i Norge. Enzymene CYP2D6 og CYP2C19 er sentrale i metabolismen av SSRI-antidepressiver. Serotonintransportøren kodet av SLC6A4 kan ha betydning for effekten av medikamentene.<p> <p>MATERIALE OG METODE - Alle pasienter som hadde blitt genotypet for CYP2D6, CYP2C19 og SLC6A4 ved Senter for psykofarmakologi i ... -
Genome-wide expression and methylation analyses reveal aberrant cell adhesion signaling in tyrosine kinase inhibitor-resistant CML cells
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-22)Although chronic myeloid leukemia (CML) can be effectively treated using BCR‑ABL1 kinase inhibitors, resistance due to kinase alterations or to BCR‑ABL1 independent mechanisms remain a therapeutic challenge. For the latter, the underlying mechanisms are widely discussed; for instance, gene expression changes, epigenetic factors and alternative signaling pathway activation. In the present study, in ... -
GIPAW Pseudopotentials of d Elements for Solid-State NMR
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-06)Computational methods are increasingly used to support interpreting, assigning and predicting the solid-state nuclear resonance magnetic spectra of materials. Currently, density functional theory is seen to achieve a good balance between efficiency and accuracy in solid-state chemistry. To be specific, density functional theory allows the assignment of signals in nuclear resonance magnetic spectra ... -
Markers of cellular senescence is associated with persistent pulmonary pathology after COVID-19 infection
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-19)Background: The lungs are the organ most likely to sustain serious injury from coronavirus disease 2019 (COVID-19). However, the mechanisms for long-term complications are not clear. Patients with severe COVID-19 have shorter telomere lengths and higher levels of cellular senescence, and we hypothesized that circulating levels of the telomere-associated senescence markers chitotriosidase, ... -
Inflammatory Markers and Radiotherapy Response in Patients With Painful Bone Metastases
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-05)<p><b> Context</b> Inflammation is proposed to influence tumor response in radiotherapy (RT). Clinical studies to investigate the relationship between inflammatory markers and RT response is warranted to understand the variable RT efficacy in patients with painful bone metastases. <p><b> Objectives</b> To evaluate the association between inflammatory markers and analgesic response to RT in ... -
The role of avalanche education in assessing and judging avalanche risk factors
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-07)Avalanche decision-making falls into two general categories; probabilistic approaches and analytical approaches. Analytical approaches have traditionally been considered applicable to experts only, as they require assessing risk factors precisely and understanding their relevance in each situation. In this study we question this assumption. We asked 1,220 amateur backcountry recreationalists how ... -
Satellite detection of snow avalanches using Sentinel-1 in a transitional snow climate
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-18)Snow avalanches endanger lives and infrastructure in mountainous regions worldwide. Consistent and accurate datasets of avalanche events are critical for improving hazard forecasting and understanding the spatial and temporal patterns of avalanche activity. Remote sensing-based identification of avalanche debris allow for the acquisition of continuous and spatially consistent avalanches datasets. ... -
Source-sink dynamics drove punctuated adoption of early pottery in Arctic Europe under diverging socioecological conditions
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-25)What drives the adoption of pottery amongst prehistoric foragers in high-latitude environments? Following the long-running interests of archaeology in explaining the origin and dispersal of new technologies, recent years have seen growing efforts to understand what drove the emergence and expansion of early hunter-gatherer pottery use across northern Eurasia. However, many regional dimensions to ... -
Benthic dissolved silicon and iron cycling at glaciated Patagonian fjord heads
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-18)Glacier meltwater supplies silicon (Si) and iron (Fe) sourced from weathered bedrock to downstream ecosystems. However,the extent to which these nutrients reach the ocean is regulated by the nature of the benthic cycling of dissolved Siand Fewithin fjord systems,given the rapid deposition of reactive particulate fractions at fjord heads. Here, we examine the benthic cycling of the two nutrients at ... -
Offered Support and Knowledge about the Menstrual Cycle in the Athletic Community: A Cross-Sectional Study of 1086 Female Athletes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-21)Many female athletes perceive that symptoms related to the menstrual cycle such as dysmenorrhea, premenstrual symptoms, amenorrhea or side-effects of hormonal contraceptives negatively impact their training, performance, and general well-being. Knowledge and communication about female athletes’ health is therefore important in the sport community. The aims of this study were to explore the level ... -
A scoping review of diabetes telemedicine research in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-22)The recent pandemic highlighted telemedicine’s potential for continuity of remote diabetes patients’ care. The study objective was to identify diabetes telemedicine services, benefits, and challenges in Norway. We searched for publications on the topic in PubMed, ScienceDirect, CINAHL, and Nora. Most of the included studies (7/15) focused on telemedicine for type 2 diabetes. Telemedicine benefits ... -
Impacts on biodiversity from codend and fisher selection in bottom trawl fishing
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-22)Fisheries have important impacts on marine biodiversity. In this work, combined information on the abundance, species richness, diversity indices, species composition, trophic level and vulnerability index were examined for the first-time to detect differences in five units related to trawl fishing: the fish assemblage entering the trawl codend, and the escaping, retained, discarded and landed ...