dc.contributor.author | Helle, Øystein Ivar | |
dc.contributor.author | Øie, Cristina Ionica | |
dc.contributor.author | McCourt, Peter Anthony | |
dc.contributor.author | Ahluwalia, Balpreet Singh | |
dc.date.accessioned | 2016-03-15T07:48:35Z | |
dc.date.available | 2016-03-15T07:48:35Z | |
dc.date.issued | 2015-08-26 | |
dc.description.abstract | The evanescent field on top of optical waveguides is used to image membrane network and sieve-plates of liver
endothelial cells. In waveguide excitation, the evanescent field is dominant only near the surface (~100-150 nm)
providing a default optical sectioning by illuminating fluorophores in close proximity to the surface and thus benefiting
higher signal-to-noise ratio. The sieve plates of liver sinusoidal endothelial cells are present on the cell membrane, thus
near-field waveguide chip-based microscopy configuration is preferred over epi-fluorescence. The waveguide chip is
compatible with optical fiber components allowing easy multiplexing to different wavelengths. In this paper, we will
discuss the challenges and opportunities provided by integrated optical microscopy for imaging cell membranes. | en_US |
dc.description | Source at <a href=https://doi.org/10.1117/12.2187277>https://doi.org/10.1117/12.2187277</a>. | en_US |
dc.identifier.citation | Helle, Ø.I., Øie, C.I., McCourt, P. & Ahluwalia, B.S. (2015). Chip-based optical microscopy for imaging membrane sieve plates of liver scavenger cells. <i>Proceedings of SPIE, 9554</i>, Nanoimaging and Nanospectroscopy III, 95540O. https://hdl.handle.net/10037/16641 | en_US |
dc.identifier.cristinID | FRIDAID 1275989 | |
dc.identifier.doi | 10.1117/12.2187277 | |
dc.identifier.issn | 0277-786X | |
dc.identifier.uri | https://hdl.handle.net/10037/8943 | |
dc.identifier.urn | URN:NBN:no-uit_munin_8537 | |
dc.language.iso | eng | en_US |
dc.publisher | Society of Photo-optical Instrumentation Engineers | en_US |
dc.relation.ispartof | Helle, Ø.I. (2019). On-chip optical nanoscopy: towards high throughput and multi-modality. (Doctoral thesis). <a href=https://hdl.handle.net/10037/16641>https://hdl.handle.net/10037/16641. </a> | |
dc.rights.accessRights | openAccess | |
dc.subject | VDP::Teknologi: 500::Medisinsk teknologi: 620 | en_US |
dc.subject | VDP::Technology: 500::Medical technology: 620 | en_US |
dc.title | Chip-based optical microscopy for imaging membrane sieve plates of liver scavenger cells | en_US |
dc.type | Journal article | en_US |
dc.type | Tidsskriftartikkel | en_US |
dc.type | Peer reviewed | en_US |