• Food biodiversity and total and cause-specific mortality in 9 European countries: An analysis of a prospective cohort study 

      Hanley-Cook, Giles T.; Huybrechts, Inge; Biessy, Carine; Remans, Roseline; Kennedy, Gina; Deschasaux-Tanguy, Mélanie; Murray, Kris A.; Touvier, Mathilde; Skeie, Guri; Kesse-Guyot, Emmanuelle; Argaw, Alemayehu; Casagrande, Corinne; Nicolas, Geneviève; Vineis, Paolo; Millett, Christopher J.; Weiderpass, Elisabete; Ferrari, Pietro; Dahm, Christina C.; Bueno-De-Mesquita, H. Bas; Sandanger, Torkjel M; Ibsen, Daniel B.; Freisling, Heinz; Ramne, Stina; Jannasch, Franziska; van der Schouw, Yvonne T.; Schulze, Matthias B.; Tsilidis, Konstantinos K.; Tjønneland, Anne; Ardanaz, Eva; Bodén, Stina; Cirera, Lluís; Gargano, Giuliana; Halkjær, Jytte; Jakszyn, Paula; Johansson, Ingegerd; Katzke, Verena; Masala, Giovanna; Panico, Salvatore; Rodriguez-Barranco, Miguel; Sacerdote, Carlotta; Srour, Bernard; Tumino, Rosario; Riboli, Elio; Gunter, Marc J.; Jones, Andrew D.; Lachat, Carl (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-18)
      Background<p> <p>Food biodiversity, encompassing the variety of plants, animals, and other organisms consumed as food and drink, has intrinsic potential to underpin diverse, nutritious diets and improve Earth system resilience. Dietary species richness (DSR), which is recommended as a crosscutting measure of food biodiversity, has been positively associated with the micronutrient adequacy of diets ...
    • Food processing and cancer risk in Europe: results from the prospective EPIC cohort study 

      Kliemann, Nathalie; Rauber, Fernanda; Bertazzi Levy, Renata; Viallon, Vivian; Vamos, Eszter P; Cordova, Reynalda; Freisling, Heinz; Casagrande, Corinne; Nicolas, Genevieve; Aune, Dagfinn; Tsilidis, Konstantinos K; Heath, Alicia; Schulze, Matthias B; Jannasch, Franziska; Srour, Bernard; Kaaks, Rudolf; Rodriguez-Barranco, Miguel; Tagliabue, Giovanna; Agudo, Antonio; Panico, Salvatore; Ardanaz, Eva; Chirlaque, María-Dolores; Vineis, Paolo; Tumino, Rosario; Perez-Cornago, Aurora; Andersen, Julie Louise Munk; Tjønneland, Anne; Skeie, Guri; Weiderpass, Elisabete; Monteiro, Carlos Augusto; Gunter, Marc J; Millett, Christopher; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-06)
      Background - Food processing has been hypothesised to play a role in cancer development; however, data from large-scale epidemiological studies are scarce. This study investigated the association between dietary intake according to amount of food processing and risk of cancer at 25 anatomical sites using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) study.<p> ...
    • Fruit and vegetable consumption in relation to hepatocellular carcinoma in a multi-centre, European cohort study 

      Bamia, Christina; Lagiou, Pagona; Jenab, Mazda; Aleksandrova, Krasimira; Fedirko, Veronika; Trichopoulos, Dimitrios; Overvad, Kim; Tjønneland, Anne; Olsen, Anja; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Katzke, Verena A.; Kühn, Tilman; Boeing, Heiner; Nöthlings, Ute; Palli, Domenico; Sieri, Sabina; Panico, Salvatore; Tumino, Rosaria; Naccarati, Allessio; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.M.; Weiderpass, Elisabete; Skeie, Guri; Quirós, José Ramón; Agudo, Antonio; Chirlaque, María-Dolores; Sánchez, María-José; Ardanaz, Eva; Dorronsoro, Miren; Ericson, Ulrika; Nilsson, Lena Maria; Wennberg, Maria; Khaw, Kay-Tee; Wareham, Nicholas J.; Key, Timothy J.; Travis, Ruth C.; Ferrari, Pietro; Stepien, Magdalena; Duarte-Salles, Talita; Norat, Teresa; Murphy, Neil; Riboli, Eilo; Trichopoulou, Antonia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-05)
      Background: Vegetable and/or fruit intakes in association with hepatocellular carcinoma (HCC) risk have been investigated in case–control studies conducted in specific European countries and cohort studies conducted in Asia, with inconclusive results. No multi-centre European cohort has investigated the indicated associations. Methods: In 486 799 men/women from the European Prospective Investigation ...
    • Haem iron intake and risk of lung cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Ward, Heather A; Whitman, Julia; Muller, David C; Johansson, Mattias; Jakszyn, Paula; Weiderpass, Elisabete; Palli, Domenico; Fanidi, Anouar; Vermeulen, Roel; Tjønneland, Anne; Hansen, Louise; Dahm, Christina C.; Overvad, Kim; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Affret, Aurélie; Kaaks, Rudolf; Fortner, Renee; Boeing, Heiner; Trichopoulou, Antonia; La Vecchia, Carlo; Kotanidou, Anastasia; Berrino, Franco; Krogh, Vittorio; Tumino, Rosario; Ricceri, Fulvio; Panico, Salvatore; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Quirós, José Ramón; Agudo, Antonio; Rodríguez-Barranco, Miguel; Larrañaga, Nerea; Huerta, Jose Maria; Ardanaz, Eva; Drake, Isabel; Brunnström, Hans; Johansson, Mikael; Grankvist, Kjell; Travis, Ruth C.; Freisling, Heinz; Stepien, Magdalena; Merritt, Melissa A.; Riboli, Elio; Cross, Amanda J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-18)
      <p><i>Background</i>: Epidemiological studies suggest that haem iron, which is found predominantly in red meat and increases endogenous formation of carcinogenic N-nitroso compounds, may be positively associated with lung cancer. The objective was to examine the relationship between haem iron intake and lung cancer risk using detailed smoking history data and serum cotinine to control for potential ...
    • Healthy lifestyle and risk of cancer in the European prospective investigation into cancer and nutrition cohort study 

      McKenzie, Fiona; Biessy, Carine; Ferrari, Pietro; Freisling, Heinz; Rinaldi, Sabina; Chajes, Veronique; Dahm, Christina C; Overvad, Kim; Dossus, Laure; Lagiou, Pagona; Trichopoulos, Dimitrios; Trichopoulou, Antonia; Bas Bueno-De-Mesquita, H; May, Anne; Peeters, Petra H; Weiderpass, Elisabete; Sanchez, Maria-Jose; Navarro, Carmen; Ardanaz, Eva; Ericson, Ulrica; Wirfalt, Elisabet; Travis, Ruth C; Romieu, Isabelle (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04)
      It has been estimated that at least a third of the most common cancers are related to lifestyle and as such are preventable. Key modifiable lifestyle factors have been individually associated with cancer risk; however, less is known about the combined effects of these factors. This study generated a healthy lifestyle index score (HLIS) to investigate the joint effect of modifiable factors on ...
    • Healthy lifestyle and the risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition study 

      Naudin, Sabine; Margalef, Marta Solans; Saberi Hosnijeh, Fatemeh; Nieters, Alexandra; Kyrø, Cecilie; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Mahamat-Saleh, Yahya; Besson, Caroline; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Canzian, Federico; Schulze, Matthias B.; Peppa, Eleni; Karakatsani, Anna; Trichopoulou, Antonia; Sieri, Sabina; Masala, Giovana; Panico, Salvatore; Tumino, Rosario; Ricceri, Fulvio; Chen, Sairah Lai Fa; Barroso, Leila L.; Huerta, José María; Sánchez, Maria-Jose; Ardanaz, Eva; Menéndez, Virginia; Exezarreta, Pilar Amiano; Spaeth, Florentin; Jerkeman, Mats; Jirstom, Karin; Schmidt, Julie A.; Aune, Dagfinn; Weiderpass, Elisabete; Riboli, Elio; Vermeulen, Roel; Casabonne, Delphine; Gunter, Marc; Brennan, Paul; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-16)
      Limited evidence exists on the role of modifiable lifestyle factors on the risk of lymphoma. In this work, the associations between adherence to healthy lifestyles and risks of Hodgkin lymphoma (HL) and non‐Hodgkin lymphoma (NHL) were evaluated in a large‐scale European prospective cohort. Within the European Prospective Investigation into Cancer and Nutrition (EPIC), 2,999 incident lymphoma cases ...
    • Healthy lifestyle and the risk of pancreatic cancer in the EPIC study 

      Naudin, Sabine; Viallon, Vivian; Hashim, Dana; Freisling, Heinz; Jenab, Mazda; Weiderpass, Elisabete; Perrier, Flavie; McKenzie, Fiona; Bueno-de-Mesquita, Hendrik Bastiaan; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Mancini, Francesca R.; Rebours, Vinciane; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kaaks, Rudolf; Bergmann, Manuela; Boeing, Heiner; Peppa, Eleni; Karakatsani, Anna; Trichopoulou, Antonia; Pala, Valeria; Masala, Giovana; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; May, Anne M.; van Gils, Carla H.; Rylander, Charlotta; Borch, Kristin Benjaminsen; Chirlaque López, María Dolores; Sánchez, Mariá-José; Ardanaz, Eva; Quirós, José Ramón; Amiano Exezarreta, Pilar; Sund, Malin; Drake, Isabel; Regnér, Sara; Travis, Ruth C.; Wareham, Nick; Aune, Dagfinn; Riboli, Elio; Gunter, Marc J.; Duell, Eric J.; Brennan, Paul; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-28)
      Pancreatic cancer (PC) is a highly fatal cancer with currently limited opportunities for early detection and effective treatment. Modifiable factors may offer pathways for primary prevention. In this study, the association between the Healthy Lifestyle Index (HLI) and PC risk was examined. Within the European Prospective Investigation into Cancer and Nutrition cohort, 1113 incident PC (57% women) ...
    • Inflammatory potential of the diet and association with risk of differentiated thyroid cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Lécuyer, Lucie; Laouali, Nasser; Dossus, Laure; Shivappa, Nitin; Hébert, James R.; Agudo, Antonio; Tjonneland, Anne; Halkjaer, Jytte; Overvad, Kim; Katzke, Verena A.; Le Cornet, Charlotte; Schulze, Matthias B.; Jannasch, Franziska; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Dragna, Luca; Iannuzzo, Gabriella; Jensen, Torill Miriam Enget; Brustad, Magritt; Skeie, Guri; Zamora-Ros, Raul; Rodriguez-Barranco, Miguel; Amiano, Pilar; Chirlaque, María-Dolores; Ardanaz, Eva; Almquist, Martin; Sonestedt, Emily; Sandström, Maria; Nilsson, Lena Maria; Weiderpass, Elisabete; Huybrechts, Inge; Rinaldi, Sabina; Boutron-Ruault, Marie-Christine; Truong, Thérèse (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-30)
      Purpose - Chronic inflammation is thought to initiate or promote differentiated thyroid cancer (DTC) and previous studies have shown that diet can modulate this inflammatory process. We aimed to evaluate the association of several dietary scores reflecting the inflammatory potential of the diet with DTC risk.<p> <p>Methods - Within the EPIC cohort, 450,063 participants were followed during a mean ...
    • Insulin-like growth factor I and risk of epithelial invasive ovarian cancer by tumour characteristics: Results from the EPIC cohort 

      Ose, Jennifer; Fortner, Renée T; Schock, Helena; Peeters, Petra H.; Onland-Moret, N. Charlotte; Bueno-de-Mesquita, H. Bas; Weiderpass, Elisabete; Gram, Inger Torhild; Overvad, Kim; Tjønneland, Anne; Dossus, Laure; Fournier, Agnes; Baglietto, Laura; Trichopoulou, Antonia; Benetou, Vassiliki; Trichopoulos, Dimitrios; Boeing, Heiner; Masala, Giovanna; Krogh, Vittorio; Matiello, Amalia; Tumino, Rosaria; Popovic, Maja; Obón-Santacana, Mireia; Larrañaga, Nerea; Ardanaz, Eva; Sánchez, María-José; Menéndez, Virginia; Chirlaque, María-Dolores; Travis, Ruth C.; Khaw, Kay-Tee; Brändstedt, Jenny; Idahl, Annika; Lundin, Eva; Rinaldi, Sabina; Kuhn, Elisabetta; Romieu, Isabelle; Gunter, Marc J.; Merritt, Melissa A.; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11-04)
      Background: Prospective studies on insulin-like growth factor I (IGF-I) and epithelial ovarian cancer (EOC) risk are inconclusive. Data suggest risk associations vary by tumour characteristics.<p> <p>Methods: We conducted a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate IGF-I concentrations and EOC risk by tumour characteristics ...
    • Lifestyle correlates of eight breast cancer-related metabolites: a cross-sectional study within the EPIC cohort 

      His, Mathilde; Viallon, Vivian; Dossus, Laure; Schmidt, Julie A.; Travis, Ruth C.; Gunter, Marc; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Lécuyer, Lucie; Rothwell, Joseph A.; Severi, Gianluca; Johnson, Theron; Katzke, Verena; Schulze, Matthias B.; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Macciotta, Alessandra; Boer, Jolanda M. A.; Monninkhof, Evelyn; Olsen, Karina Standahl; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Agudo, Antonio; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Ardanaz, Eva; Vidman, Linda; Winkvist, Anna; Heath, Alicia K.; Weiderpass, Elisabete; Huybrechts, Inge; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-10)
      Background: Metabolomics is a promising molecular tool for identifying novel etiological pathways leading to cancer. In an earlier prospective study among pre- and postmenopausal women not using exogenous hormones, we observed a higher risk of breast cancer associated with higher blood concentrations of one metabolite (acetylcarnitine) and a lower risk associated with higher blood concentrations of ...
    • Lifetime alcohol intake, drinking patterns over time and risk of stomach cancer: A pooled analysis of data from two prospective cohort studies 

      Jayasekara, Harindra; MacInnis, Robert J.; Lujan-Barroso, Leila; Mayen-Chacon, Ana-Lucia; Cross, Amanda J.; Wallner, Bengt; Palli, Domenico; Ricceri, Fulvio; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Kühn, Tilman; Kaaks, Rudolf; Tsilidis, Konstantinos K.; Sánchez, Maria-Jose; Amiano, Pilar; Ardanaz, Eva; Chirlaque López, María Dolores; Merino, Susana; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Sternby, Hanna; Sonestedt, Emily; Bueno-de-Mesquita, Bas; Boeing, Heiner; Travis, Ruth C.; Sandanger, Torkjel M; Trichopoulou, Antonia; Karakatsani, Anna; Peppa, Eleni; Tjønneland, Anne; Yang, Yi; Hodge, Allison M.; Mitchell, Hazel; Haydon, Andrew; Room, R; Hopper, John L.; Weiderpass, Elisabete; Gunter, Marc J.; Riboli, Elio; Giles, Graham G.; Milne, Roger L.; Agudo, Antonio; English, Dallas R.; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-07)
      Alcohol consumption is causally linked to several cancers but the evidence for stomach cancer is inconclusive. In our study, the association between long-term alcohol intake and risk of stomach cancer and its subtypes was evaluated. We performed a pooled analysis of data collected at baseline from 491 714 participants in the European Prospective Investigation into Cancer and Nutrition and the Melbourne ...
    • Long-term weight change and risk of breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study 

      Ellingjord-Dale, Merete; Christakoudi, Sofia; Weiderpass, Elisabete; Panico, Salvatore; Dossus, Laure; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Schulze, Matthias B.; Masala, Giovanna; Gram, Inger Torhild; Skeie, Guri; Rosendahl, Ann H.; Sund, Malin; Key, Tim; Ferrari, Pietro; Gunter, Marc; Heath, Alicia K; Tsilidis, Konstantinos K; Riboli, Eilo; Sánchez, Maria-Jose; Lopez, Maria-Dolores Chirlaque; Peppa, Eleni; Trichopoulou, Antonia; Martimianaki, Georgia; Agudo, Antonio; Santiuste, Carmen; Ardanaz, Eva; Amiano, Pilar; Boutron-Ruault, Marie-Chiristine; Simeon, Vittorio; Berrino, Franco; Tumino, Rosario; Severi, Gianluca; Stocks, Tanja; Turzanski-Fortner, Renée; Rylander, Charlotta; Aune, Dagfinn; Dahm, Christina Catherine (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-23)
      Background: The role of obesity and weight change in breast-cancer development is complex and incompletely understood. We investigated long-term weight change and breast-cancer risk by body mass index (BMI) at age 20 years, menopausal status, hormone replacement therapy (HRT) and hormone-receptor status.<p><p> Methods: Using data on weight collected at three different time points from women ...
    • Main nutrient patterns and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study 

      Moskal, Aurelie; Freisling, Heinz; Byrnes, Graham; Assi, Nada; Fahey, Michael T.; Jenab, Mazda; Ferrari, Pietro; Tjønneland, Anne; Petersen, Kristina E N; Dahm, Christina C; Hansen, Camilla Plambeck; Affret, Aurélie; Boutron-Ruault, Marie-Christine; Cadeau, Claire; Kuhn, Tilman; Katzke, Verena; Iqbal, Khalid; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; Naska, Androniki; Masala, Giovanna; de Magistris, Maria Santucci; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Peeters, Petra H; Bueno-de-Mesquita, Bas H; Engeset, Dagrun; Licaj, Idlir; Skeie, Guri; Ardanaz, Eva; Buckland, Genevieve; Castaño, José María Huerta; Quirós, José R.; Amiano, Pilar; Molina-Portillo, Elena; Winkvist, Anna; Myte, Robin; Ericson, Ulrika; Sonestedt, Emily; Perez-Cornago, Aurora; Wareham, Nick; Khaw, Kay-Tee; Huybrechts, Inge; Tsilidis, Konstantinos K; Ward, Heather; Gunter, Marc J; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-20)
      Background: Much of the current literature on diet–colorectal cancer (CRC) associations focused on studies of single foods/ nutrients, whereas less is known about nutrient patterns. We investigated the association between major nutrient patterns and CRC risk in participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. <p>Methods: Among 477 312 participants, ...
    • Measured adiposity in relation to head and neck cancer risk in the European prospective investigation into cancer and nutrition. 

      Ward, Heather A.; Wark, Petra A.; Muller, David C.; Steffen, Annika; Johansson, Mattias; Norat, Teresa; Gunter, Marc J.; Overvad, Kim; Dahm, Christina C; Halkjær, Jytte; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Mesrine, Sylvie; Brennan, Paul; Freisling, Heinz; Li, Kuanrong; Kaaks, Rudolf; Trichopoulou, Antonia; Lagiou, Pagona; Panico, Salavatore; Grioni, Sara; Tumino, Rosario; Vineis, Paolo; Palli, Domenico; Peeters, Petra H.M.; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete; Agudo, Antonio; Quirós, José Ramón; Larrañaga, Nerea; Ardanaz, Eva; Huerta, José María; Sánchez, María-José; Laurell, Göran; Johansson, Ingegerd; Westin, Ulla; Wallström, Peter; Bradbury, Kathryn E.; Wareham, Nicholas J.; Khaw, Kay-Tee; Pearson, Clare; Boeing, Heiner; Riboli, Elio (Journal article; Tidsskriftartikkel, 2017-06)
      <b>Background</b>: Emerging evidence from cohort studies indicates that adiposity is associated with greater incidence of head and neck cancer. However, most studies have used self-reported anthropometry which is prone to error.<br><b>Methods</b>: Among 363,094 participants in the European Prospective Investigation into Cancer and Nutrition study (EPIC) with measured anthropometry, there were 837 ...
    • Mediating Role of Lifestyle Behaviors in the Association between Education and Cancer: Results from the European Prospective Investigation into Cancer and Nutrition 

      Macciotta, Alessandra; Catalano, Alberto; Giraudo, Maria Teresa; Weiderpass, Elisabete; Ferrari, Pietro; Freisling, Heinz; Colorado-Yohar, Sandra M.; Santiuste, Carmen; Amiano, Pilar; Heath, Alicia K.; Ward, Heather A.; Christakoudi, Sofia; Vineis, Paolo; Singh, Deependra; Vaccarella, Salvatore; Schulze, Matthias B.; Hiensch, Anouk E.; Monninkhof, Evelyn M.; Katzke, Verena; Kaaks, Rudolf; Tumino, Rosario; Lazzarato, Fulvio; Milani, Lorenzo; Agudo, Antonio; Dahm, Christina C.; Baglietto, Laura; Perduca, Vittorio; Severi, Gianluca; Grioni, Sara; Panico, Salvatore; Ardanaz, Eva; Borch, Kristin Benjaminsen; Benebo, Faith Owunari; Braaten, Tonje; Sánchez, Maria-Jose; Giachino, Claudia; Sacerdote, Carlotta; Ricceri, Fulvio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-09)
      Background: Many studies have shown that socioeconomic position (SEP) is associated with the incidence of malignant tumors at different sites. This study aims to estimate the association between educational level (as proxy for SEP) and cancer incidence and to understand whether the observed associations might be partially explained by lifestyle behaviors.<p> <p>Methods: The analyses were performed ...
    • Mediterranean diet and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition cohort 

      Molina-Montes, Esther; Sánchez, María-José; Buckland, Genevieve; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete; Amiano, Pilar; Wark, Petra A.; Kühn, Tilman; Katzke, Verena; Huerta, José María; Ardanaz, Eva; Quirós, José Ramón; Affret, Aurelie; His, Mathilde; Boutron-Ruault, Marie-Christine; Peeters, Petra H.; Ye, Weimin; Sund, Malin; Boeing, Heiner; Iqbal, Khalid; Ohlsson, Bodil; Sonestedt, Emily; Tjønneland, Anne; Petersen, Kristina E.N.; Travis, Ruth C.; Skeie, Guri; Agnoli, Claudia; Panico, Salvatore; Palli, Domenico; Tumino, Rosario; Sacerdote, Carlotta; Freisling, Heinz; Huybrechts, Inge; Overvad, Kim; Trichopoulou, Antonia; Bamia, Christina; Vasilopoulou, Effie; Wareham, Nick; Khaw, Kay-Tee; Cross, Amanda J.; Ward, Heather A.; Riboli, Elio; Duell, Eric J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-07)
      Background: The Mediterranean diet (MD) has been proposed as a means for cancer prevention, but little evidence has been accrued regarding its potential to prevent pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. <br>Methods: Over half a million ...
    • Methodological issues in a prospective study on plasma concentrations of persistent organic pollutants and pancreatic cancer risk within the EPIC cohort 

      Gasull, Magda; Pumarega, José; Kiviranta, Hannu; Rantakokko, Panu; Raaschou-Nielsen, Ole; Bergdahl, Ingvar A.; Sandanger, Torkjel M; Goñi, Fernando; Cirera, Lluís; Donat-Vargas, Carolina; Alguacil, Juan; Iglesias, Mar; Tjønneland, Anne; Overvad, Kim; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Johnson, Theron; Kühn, Tilman; Trichopoulou, Antonia; Karakatsani, Anna; Peppa, Eleni; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Naccarati, Alessio; Panico, Salvatore; Verschuren, Monique; Vermeulen, Roel; Rylander, Charlotta; Nøst, Therese Haugdahl; Rodriguez-Barranco, Miguel; Molinuevo, Amaia; Chirlaque, Maria-Dolores; Ardanaz, Eva; Sund, Malin; Key, Tim; Ye, Weimin; Jenab, Mazda; Michaud, Dominique; Matullo, Giuseppe; Canzian, Federico; Kaaks, Rudolf; Nieters, Alexandra; Nöthlings, Ute; Jeurnink, Suzanne; Chajes, Veronique; Matejcic, Marco; Gunter, Marc; Aune, Dagfinn; Riboli, Elio; Agudo, Antoni; Gonzalez, Carlos Alberto; Weiderpass, Elisabete; Bueno-de-Mesquita, Hendrik Bastiaan; Duell, Eric J.; Vineis, Paolo; Porta, Miquel (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-23)
      <i>Background</i> - The use of biomarkers of environmental exposure to explore new risk factors for pancreatic cancer presents clinical, logistic, and methodological challenges that are also relevant in research on other complex diseases.<p> <p><i>Objectives</i> - First, to summarize the main design features of a prospective case-control study –nested within the European Prospective Investigation ...
    • Modifiable causes of premature death in middle-age in Western Europe: Results from the EPIC cohort study 

      Muller, David C.; Murphy, Neil; Johansson, Mattias; Ferrari, Pietro; Tsilidis, Konstantinos K.; Boutron-Ruault, Marie-Christine; Clavel, Francoise; Dartois, Laureen; Li, Kuanrong; Kaaks, Rudolf; Weikert, Cornelia; Bergmann, Manuela; Boeing, Heiner; Tjønneland, Anne; Overvad, Kim; Redondo, María-Luisa; Agudo, Antonio; Molina-Portillo, Elena; Altzibar, Jone M.; Cirera, Lluis; Ardanaz, Eva; Khaw, Kay-Tee; Wareham, Nicholas J.; Key, Timothy J.; Travis, Ruth C.; Bamia, Christina; Orfanos, Philippos; Trichopoulou, Antonia; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Verschuren, W.M. Monique; Struijk, Ellen A.; Peeters, Petra H.; Engström, Gunnar; Melander, Olle; Sund, Malin; Weiderpass, Elisabete; Skeie, Guri; Lund, Eiliv; Norat, Teresa; Gunter, Marc; Riboli, Elio; Brennan, Paul (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-14)
      Background<br> Life expectancy is increasing in Europe, yet a substantial proportion of adults still die prematurely before the age of 70 years. We sought to estimate the joint and relative contributions of tobacco smoking, hypertension, obesity, physical inactivity, alcohol and poor diet towards risk of premature death.<br> Methods<br> We analysed data from 264,906 European adults from the ...
    • A new pipeline for the normalization and pooling of metabolomics data 

      Viallon, Vivian; His, Mathilde; Rinaldi, Sabina; Breeur, Marie; Gicquiau, Audrey; Hémon, Bertrand; Overvad, Kim; Tjønneland, Anne; Rostgaard-Hansen, Agnetha Linn; Rothwell, Joseph A.; Lecuyer, Lucie; Severi, Gianluca; Kaaks, Rudolf; Johnson, Theron; Schulze, Matthias B.; Palli, Domenico; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosaria; Ricceri, Fulvio; Monique Verschuren, Verschuren; Engelfriet, Peter; Onland-Moret, Charlotte; Vermeulen, Roel; Nøst, Therese Haugdahl; Urbarova, Ilona; Zamora-Ros, Raul; Rodríguez-Barranco, Miguel; Amiano, Pilar; Huerta, José María; Ardanaz, Eva; Melander, Olle; Ottoson, Filip; Vidman, Linda; Rentoft, Matilda; Schmidt, Julie A.; Travis, Ruth C.; Weiderpass, Elisabete; Johansson, Mattias; Dossus, Laure; Jenab, Mazda; Gunter, Marc; Bermejo, Justo Lorenzo; Scherer, Dominique; Salek, Reza M.; Keski-Rahkonen, Pekka; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-17)
    • Novel Biomarkers of Habitual Alcohol Intake and Associations With Risk of Pancreatic and Liver Cancers and Liver Disease Mortality 

      Loftfield, Erikka; Stepien, Magdalena; Viallon, Vivian; Trijsburg, Laura; Rothwell, Joseph A.; Robinot, Nivonirina; Biessy, Carine; Bergdahl, Ingvar A.; Bodén, Stina; Schulze, Matthias B.; Bergman, Manuela; Weiderpass, Elisabete; Schmidt, Julie A.; Zamora-Ros, Raúl; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Sonestedt, Emily; Ohlsson, Bodil; Katzke, Verena; Kaaks, Rudolf; Ricceri, Fulvio; Tjønneland, Anne; Dahm, Christina C.; Sánchez, Maria-Jose; Trichopoulou, Antonia; Tumino, Rosario; Chirlaque, María-Dolores; Masala, Giovanna; Ardanaz, Eva; Vermeulen, Roel; Brennan, P; Albanes, Demetrius; Weinstein, Stephanie J.; Scalbert, Augustin; Freedman, Neal D.; Gunter, Marc; Jenab, Mazda; Sinha, Rashmi; Keski-Rahkonen, Pekka; Ferrari, Pietro (Preprint; Manuskript, 2021-05-19)
      Background - Alcohol is an established risk factor for several cancers, but modest alcohol-cancer associations may be missed because of measurement error in self-reported assessments. Biomarkers of habitual alcohol intake may provide novel insight into the relationship between alcohol and cancer risk.<p> <p>Methods - Untargeted metabolomics was used to identify metabolites correlated with ...