Munin: Recent submissions
Now showing items 16381-16400 of 37183
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Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-18)Although oral drug delivery is the preferred administration route and has been used for centuries, modern drug discovery and development pipelines challenge conventional formulation approaches and highlight the insufficient mechanistic understanding of processes critical to oral drug absorption. This review presents the opinion of UNGAP scientists on four key themes across the oral absorption ... -
Survey of European neurosurgeons’ management of unruptured intracranial aneurysms: inconsistent practice and organization
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-01)Background - The discovery of an unruptured intracranial aneurysm creates a dilemma between observation and treatment. Neurosurgeons’ routines for risk assessment and treatment decision-making are unknown. The position of evidence-based medicine in European neurosurgery is considered to be weak, high-grade guidelines do not exist and variations between institutions are probable. We aimed to explore ... -
Path planning and collision avoidance for autonomous surface vehicles I: a review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-29)Autonomous surface vehicles are gaining increasing attention worldwide due to the potential benefits of improving safety and efficiency. This has raised the interest in developing methods for path planning that can reduce the risk of collisions, groundings, and stranding accidents at sea, as well as costs and time expenditure. In this paper, we review guidance, and more specifically, path planning ... -
Path planning and collision avoidance for autonomous surface vehicles II: a comparative study of algorithms
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-06)Artificial intelligence is an enabling technology for autonomous surface vehicles, with methods such as evolutionary algorithms, artificial potential fields, fast marching methods, and many others becoming increasingly popular for solving problems such as path planning and collision avoidance. However, there currently is no unified way to evaluate the performance of different algorithms, for example ... -
Systematic identification and stratification of help-seeking school-aged youth with mental health problems: a novel approach to stage-based stepped-care
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-18)We investigated whether a novel visitation model for school-aged youth with mental health problems based on a stage-based stepped-care approach facilitated a systematic identification and stratification process without problems with equity in access. The visitation model was developed within the context of evaluating a new transdiagnostic early treatment for youth with anxiety, depressive symptoms, ... -
Making Sense of Stigmatized Organizations: Labelling Contests and Power Dynamics in Social Evaluation Processes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-12)How do social audiences negotiate and handle stigmatized organizations? What role do their heterogenous values, norms and power play in this process? Addressing these questions is important from a business ethics perspective to improve our understanding of the ethical standards against which organizations are judged as well as the involved prosecutorial incentives. Moreover, it illuminates ethical ... -
Antologiens sentrale begreper og perspektiver
(Chapter; Bokkapittel, 2021-01-08)This chapter provides an overview of key concepts and theoretical perspectives used in the anthology and points out fundamental challenges in the practice of professional welfare. ‘Competence’ and ‘knowledge’ often have different meanings, and there is a need for increased awareness of the understanding of these concepts. This chapter highlights how the managerial discretion, learning, ... -
Utøvelse av ledelse i kommunale sykehjem – handlingsrommets betydning
(Chapter; Bokkapittel, 2021-01-08)Leaders of municipal nursing homes face challenges when they seek to secure a balance between the quality demands of authorities and the services they provide. In this chapter, we present a qualitative study on the leadership challenges in the municipal nursing homes. The aim is to develop knowledge on leadership challenges and the managerial discretions leaders employ to address the challenges. ... -
A short-term musical training affects implicit emotion regulation only in behaviour but not in brain activity
(Journal article; Tidsskriftartikkel, 2021-04-26)Background: In everyday life, negative emotions can be implicitly regulated by positive stimuli, without any conscious cognitive engagement; however, the effects of such implicit regulation on mood and related neuro-mechanisms, remain poorly investigated in literature. Yet, improving implicit emotional regulation could reduce psychological burden and therefore be clinically relevant for treating ... -
Mucosal and systemic immune responses to salmon gill poxvirus infection in Atlantic salmon is modulated upon hydrocortisone injection
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-09)Salmon Gill Poxvirus Disease (SGPVD) has emerged as a cause of acute mortality in Atlantic salmon (Salmo salar L.) presmolts in Norwegian aquaculture. The clinical phase of the disease is associated with apoptotic cell death in the gill epithelium causing acute respiratory distress, followed by proliferative changes in the regenerating gill in the period after the disease outbreak. In an experimental ... -
Network Analysis: an approach to the study of drug-drug relations. Co-medication in Norwegian elderly and severe drug-drug interactions as examples
(Master thesis; Mastergradsoppgave, 2019-05-15)Network analysis (NA) has been used for studying many social aspects. Employing of network analysis as an approach in the field of public health, to study the relations between patients or health workers and their potential effects in many medical perspectives, took a good share of researchers’ efforts as well. Few attempts have been conducted to use network analysis to study drug-drug relations ... -
Microplastic Fiber Emissions From Wastewater Effluents: Abundance, Transport Behavior and Exposure Risk for Biota in an Arctic Fjord
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-07)Microfibers (MF) are one of the major classes of microplastic found in the marine environment on a global scale. Very little is known about how they move and distribute from point sources such as wastewater effluents into the ocean. We chose Adventfjorden near the settlement of Longyearbyen on the Arctic Svalbard archipelago as a case study to investigate how microfibers emitted with untreated ... -
Orphanhood and trauma in Toni Morrison's A Mercy and Beloved
(Master thesis; Mastergradsoppgave, 2018-05-15)Abstract The current thesis examines the themes trauma and orphanhood and how they are connected in Toni Morrison’s two novels A Mercy (2008) and Beloved (1987), respectively. I will examine how traumatic experiences and the notion of both literal and cultural orphanhood affects the community, and how this has changed from the story in A Mercy being set in the late 17th century and to the story in ... -
Collateral sensitivity in clinical mecillinam resistant isolates of Escherichia coli
(Master thesis; Mastergradsoppgave, 2016-05-13)Background The rapid increase in antimicrobial resistance (AMR) has become a major threat to the successful management of infectious diseases. To counteract this global threat, development of novel treatment strategies is essential. A promising strategy may be exploiting collateral sensitivity; a phenomenon that occurs when a microorganism that has developed resistance to one antimicrobial agent, ... -
In vitro intestinal digestion of lipids from the marine diatom Porosira glacialis compared to commercial LC n-3 PUFA products
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-09)Marine sources of long chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) are in high demand for use in health supplements. Mass cultivated marine microalgae is a promising and sustainable source of LC n-3 PUFA, which relieves pressure on natural fish stocks. The lipid class profile from cultivated photosynthetic algae differ from the marine organisms currently used for the production of LC n-3 ... -
Methanotrophs: Discoveries, Environmental Relevance, and a Perspective on Current and Future Applications
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-14)Methane is the final product of the anaerobic decomposition of organic matter. The conversion of organic matter to methane (methanogenesis) as a mechanism for energy conservation is exclusively attributed to the archaeal domain. Methane is oxidized by methanotrophic microorganisms using oxygen or alternative terminal electron acceptors. Aerobic methanotrophic bacteria belong to the phyla Proteobacteria ... -
The Role of Mineral Assemblages in the Environmental Impact of Cu-Sulfide Deposits: A Case Study from Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-12)Metallic mineral deposits represent natural geochemical anomalies of economically valuable commodities but, at the same time, their weathering may have negative environmental implications. Cu-sulfide mineral deposits have been recognized as deposits with a particularly large environmental footprint. However, different Cu deposits may result in significantly different environmental impacts, mostly ... -
Early spring subglacial discharge plumes fuel under-ice primary production at a Svalbard tidewater glacier
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-27)Subglacial upwelling of nutrient-rich bottom water is known to sustain elevated summer primary production in tidewater-glacier-influenced fjord systems. However, the importance of subglacial upwelling during the early spring season has not been considered yet. We hypothesized that subglacial discharge under sea ice is present in early spring and that its flux is sufficient to increase phytoplankton ... -
The Mitochondrial Genome of the Sea Anemone Stichodactyla haddoni Reveals Catalytic Introns, Insertion-Like Element, and Unexpected Phylogeny
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-28)A hallmark of sea anemone mitochondrial genomes (mitogenomes) is the presence of complex catalytic group I introns. Here, we report the complete mitogenome and corresponding transcriptome of the carpet sea anemone Stichodactyla haddoni (family Stichodactylidae). The mitogenome is vertebrate-like in size, organization, and gene content. Two mitochondrial genes encoding NADH dehydrogenase subunit 5 ... -
Are Teacher Students’ Deep Learning and Critical Thinking at Risk of Being Limited in Digital Learning Environments?
(Chapter; Bokkapittel, 2021-03-04)The 21st century is quite different from the 20th in regard to the skills people need for work, citizenship, and self-actualisation. Proficiency in the 21st century differs primarily due to the emergence of sophisticated information and communication technologies. In this chapter, we will discuss whether teaching students are sufficiently prepared regarding the need for 21st century skills and ...