Introduction: Tumor-infiltrating lymphocytes are both prognostic and predictive biomarkers for immunotherapy response. However, less is known about the survival benefits of their subpopulations.<p> <p>Methods: Using machine learning models, we assessed the clinical association of the CD8+, PD1+, TCF1+ cel l subset by multiplex immunohistochemistry using tissue microarrays in 553 non-small cell ...

Denne masteroppgaven utforsker representasjonen av globalhistorie og historiebevissthet i norske lærebøker på videregående og universitetsnivå. Gjennom en detaljert analyse av et utvalg av lærebøker, inkludert "Grunnbok i Historie" og "Perspektiver" for videregående skoler samt "Globalhistorie 1750-1900" og "Lange Linjer i Historien" for universitetsstudenter, undersøker oppgaven hvordan globalhistorie ...

Oppgaven er et blikk på forholdet mellom nasjonalisme og Meiji-restaureringen som tok sted i Japan ved midten av 1800-tallet. Oppgaven skal se på hva stillingen til nasjonalisme var før, under, og etter restaureringen. Det skal samt forklares hvordan dette vannskillepunktet i japansk historie også var et viktig steg i landet for framveksten av det moderne Japans syn på et internt fellesskap basert ...

Hvorfor er en av de veldig få enkle skafthulløksene i Nord-Norge funnet i Rødbergshamna på Lenvikhalvøya? En øksetype som forbindes med jordbruk og rydding av innmark ved slutten av steinalderen i Sør-Norge, men som her må ha befunnet seg i et jakt-, fangst - og fiskelandskap. Tromsø Museum, Universitetsmuseet ved UiT - Norges arktiske universitet, er ett av fem museer i Norge med ansvar for at funn ...

Objectives: This systematic scoping review was conducted to 1) identify and describe labor curves that illustrate cervical dilatation over time; 2) map any evidence for, as well as outcomes used to evaluate the accuracy and effectiveness of the curves; and 3) identify areas in research that require further investigation.<p><p> Methods: A three-step systematic literature search was conducted for ...

Background During the recent years, emergency services in several countries have integrated video streaming into medical emergency calls, and research on the topic has gained increased focus. Video streaming during medical emergency calls may change dispatcher’s perspective of the call and can be a helpful tool for supervising bystanders’ first aid. Little research exists, however, about the ...

Non-classical MHC class I genes which, compared to classical MHC class I, are typically less polymorphic and have more restricted expression patterns are attracting interest because of their potential to regulate immune responses to various pathogens. In salmonids, among the numerous non-classical MHC class I genes identified to date, L lineage genes, including Sasa-LIA and Sasa-LGA1, ...

The diel vertical migration (DVM) of zooplankton is one of the largest species migrations to occur globally and is a key driver of regional ecosystems and the marine carbon pump. Previously thought to be hampered by the extreme light regime prevailing in the Arctic Ocean, observations have revealed that DVM does occur in ice-covered Arctic waters and suggest the decline in Arctic sea ice may thereby ...

The sperm whale (Physeter macrocephalus) is one of the most widely distributed cetaceans. Adult males commonly occupy high latitudes, whereas females and juveniles occupy lower latitudes. In Northern Norway, previous studies focused on the summer period limiting our understanding of the seasonal dynamics of male foraging aggregations. We used year-round capture–mark–recapture data based on photo ...