Background: In individuals with schizophrenia, inflammation is associated with depression, somatic comorbidity and reduced quality of life. Physical exercise is known to reduce inflammation in other populations, but we have only limited knowledge in the field of schizophrenia. We assessed inflammatory markers in plasma samples from individuals with schizophrenia participating in an exercise intervention ...

Background - A comprehensive dissection of the role of microRNAs (miRNAs) in gene regulation and subsequent cell functions requires a specific and efficient knockdown or overexpression of the miRNA of interest; these are achieved by transfecting the cell of interest with a miRNA inhibitor or a miRNA mimic, respectively. Inhibitors and mimics of miRNAs with a unique chemistry and/or structural ...

Objective - To examine the prevalence of advanced frailty, comorbidity, and age among sepsis-related deaths in an adult hospital population.<p> <p>Methods - Retrospective chart reviews of deceased adults within a Norwegian hospital trust, with a diagnosis of infection, over 2 years (2018–2019). The likelihood of sepsis-related death was evaluated by clinicians as sepsis-related, possibly ...

The human mind wanders spontaneously and pervasively throughout daily life, pursuing trains of thought that are untethered to the world around us. Although mapping the many facets of mind wandering has become a compelling objective in the cognitive neurosciences, researchers have yet to achieve a congruous mechanistic account of its neurobiological underpinnings. In this thesis, a multidisciplinary ...

I artikkelen beskrives bruken av presens partisipp i mellomnorsk, og denne bruken sammenliknes med norrøn folkelig og lærd stil. Undersøkelsen bygger på 3208 diplom fra tidsrommet 1350–1524 med i alt 2804 forekomster av presens partisipp. Substantiverte presens partisipp beskrives kortfatta, og den sjeldne adverbiale bruken av slike partisipp registreres, men hovedfokus er på den forholdsvis utbredte ...

<p><i>Introduction:</i> Freezing cold injuries (FCI) are a common risk in extreme cold weather warfare operations. The Norwegian Armed Forces (NAF) have the expertise and capabilities in education and training for warfighting capabilities in the Arctic. Nevertheless, a substantial number of Norwegian soldiers sustain freezing cold injuries annually. The aim of this study was to describe the FCI in ...

Aims - The number of patients undergoing surgery for degenerative cervical radiculopathy has increased. In many countries, public hospitals have limited capacity. This has resulted in long waiting times for elective treatment and a need for supplementary private healthcare. It is uncertain whether the management of patients and the outcome of treatment are equivalent in public and private hospitals. ...

Background and purpose Preoperative infammatory markers, such as Glasgow prognostic score, modifed Glasgow prognostic score and C-reactive protein to albumin ratio, were shown to be associated with prognosis in patients undergoing pancreatectomy for cancer. However, little is known about their predictive role in a Western population.<p> <p>Methods The Norwegian National Registry for Gastrointestinal ...

Analysis of biological nanoparticles in medical sciences is very promising, as it can reveal groundbreaking information about disease mechanisms, potentially leading to innovative and more effective treatment strategies. The existing methods used for analyzing biological nanoparticles come with several limitations, involving extensive sample preparation, and giving limited information about the ...

Medicines are important for well-being. Thus, medication errors can have severe consequences, even death. Transfers between professionals and levels of care are a challenge in terms of medicines management. Norwegian governmental strategies encourage communication and collaboration between levels of care, and several initiatives are invested in to improve digital medicine management. In the project ...