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Prothrombotic Single Nucleotide Polymorphisms and Risk of Myocardial Infarction: A Narrative Review of the Literature
(Master thesis; Mastergradsoppgave, 2020-08-24)Background: Environmental risk factors for myocardial infarction (MI) have been extensively investigated. In addition, family history of MI is an important risk factor for the disease. Several prothrombotic genotypes are well-established risk factors for venous thrombosis. However, the role of prothrombotic genotypes as risk factors for arterial thrombosis is less emphasized. Aim: To create a ... -
Bevaring av marine områder i Norge: En studie av hvordan det norske rammeverket for bevaring av marine områder gjennomføres i praksis
(Master thesis; Mastergradsoppgave, 2022-06-02)«Bevaring av marine områder» er i utgangspunktet et samlebegrep for tiltakene «vern av marine områder» og «andre effektive arealbaserte bevaringstiltak». Norges arbeid med bevaring av marine områder er preget av et internasjonalt rammeverk med havrettskonvensjonen som overordnet rammeverk for marin forvaltning i Norge. Konvensjonen om biologisk mangfold, den internasjonale naturvernunionen (IUCN) ... -
Characteristics of hepatitis C virus resistance in an international cohort after a decade of direct-acting antivirals
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-24)Background & Aims: Direct-acting antiviral (DAA) regimens provide a cure in >95% of patients with chronic HCV infection. However, in some patients in whom therapy fails, resistance-associated substitutions (RASs) can develop, limiting retreatment options and risking onward resistant virus transmission. In this study, we evaluated RAS prevalence and distribution, including novel NS5A RASs and ... -
Comparing prevalence of chronic kidney disease and its risk factors between population-based surveys in Russia and Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-14)Background - Little data exists on the prevalence of chronic kidney disease (CKD) in the Russian population. We aimed to estimate the prevalence of CKD in a population-based study in Russia, compare with a similar study in Norway, and investigate whether differences in risk factors explained between-study differences in CKD.<p> <p>Methods - We compared age- and sex-standardised prevalence of ... -
Association between brain-derived neurotropic factor (BDNF), high-sensitivity C-reactive protein (hs-CRP) and psychiatric symptoms in medicated and unmedicated patients
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-03)Background - There is evidence that brain-derived neurotropic factor (BDNF) plays a protective role in the brain. Peripheral levels of BDNF correlate with its concentration in the brain. Previous studies have revealed lower serum BDNF levels in patients with mental illnesses. In most studies serum BDNF correlates negatively with psychiatric disorders and disease severity. Most studies in this field ... -
Epidemiology of comorbid hazardous alcohol use and insomnia in 19 185 women and men attending the population-based Tromsø Study 2015–2016
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-27)Background - Hazardous alcohol use is known to be comorbid with insomnia problems. The present study examined the prevalence of insomnia and if the odds of insomnia differed between women and men with a hazardous alcohol use.<p> <p>Methods - Cross-sectional data from the seventh survey of the Norwegian population-based Tromsø Study 2015–2016 (participation 65%). The sample included 19 185 women ... -
Joint effect of particulate matter and cigarette smoke on women’s sex hormones
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-08)Background - Although relationships between exposure to air pollution and reproductive health are broadly studied, mechanisms behind these phenomena are still unknown. The aim of the study was to assess whether exposure to particulate matter (PM10) and tobacco smoking have an impact on menstrual profiles of 17β-estradiol (E2) and progesterone (P) and the E2/P ratio.<p> <p>Methods - Levels of sex ... -
Complementary and alternative medicine modalities used to treat adverse effects of anti‑cancer treatment among children and young adults: a systematic review and meta‑analysis of randomized controlled trials
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-02)Background - Dealing with the symptom burden of cancer diagnosis and treatment has led parents to seek different self-management strategies including Alternative and Complementary Medicine (CAM). The aim of this study was to perform a systematic review and meta-analysis about the use and effect of CAM modalities to treat adverse effects of conventional cancer treatment among children and young ... -
Talking together in rural palliative care: a qualitative study of interprofessional collaboration in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-07)Background - Caring for people with palliative care needs in their homes requires close collaboration within and between primary and hospital care. However, such close collaboration is often lacking. Transitions of care are potentially unsafe and distressing points in a patient trajectory. Few studies have explored the experiences of healthcare professionals in the community who receive patients ... -
Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-11)Background - Epidemiological and experimental evidence has linked chronic inflammation to cancer aetiology. It is unclear whether associations for specific inflammatory biomarkers are causal or due to bias. In order to examine whether altered genetically predicted concentration of circulating cytokines are associated with cancer development, we performed a two-sample Mendelian randomisation (MR) ... -
Socioeconomic inequalities in physiological risk biomarkers and the role of lifestyles among Russians aged 35-69 years
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-15)Background: Socioeconomic inequalities in cardiovascular (CVD) health outcomes are well documented. While Russia has one of the highest levels of CVD mortality in the world, the literature on contemporary socio-economic inequalities in biomarker CVD risk factors is sparse. This paper aims to assess the extent and the direction of SEP inequalities in established physiological CVD risk biomarkers, ... -
Quality of Life instruments and their psychometric properties for use in parents during pregnancy and the postpartum period: a systematic scoping review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-09)Purpose: To identify instruments used to measure parents’ Quality of Life (QoL) during pregnancy and the postpartum period, and to describe their characteristics and psychometric properties.<p> <p>Methods: For this scoping review we conducted systematic literature searches in MEDLINE, EMBASE, PsychINFO, CINAHL and HaPI in mid-December 2020, to identify studies evaluating psychometric properties. ... -
The Brexit deal and UK fisheries—has reality matched the rhetoric?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-26)Fisheries management has been a strongly contested aspect of the UK’s position in the EU since UK accession, with the fshing industry frequently questioning both the efcacy and fairness of arrangements. During the campaign for UK exit (Brexit) from the EU, and the subsequent negotiations of a new legal and political relationship from 2016 to 2020, senior UK political leaders strongly committed to ... -
Identification and molecular characterization of Brucella abortus and Brucella melitensis isolated from milk in cattle in Azerbaijan
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-15)Background - Azerbaijan currently ranks thirteenth in global incidence of human brucellosis, with an estimated annual incidence through 2000 at over 50 cases per million. Brucella melitensis has been isolated from patients and is thought to have been acquired through contact with small ruminants or as a foodborne infection. To reduce the burden of human brucellosis, the Azerbaijani government began ... -
Risk factors of anemia among preschool children in Ethiopia: a Bayesian geo-statistical model
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-07)Background - The etiology and risk factors of anemia are multifactorial and varies across context. Due to the geospatial clustering of anemia, identifying risk factors for anemia should account for the geographic variability. Failure to adjust for spatial dependence whilst identifying risk factors of anemia could give spurious association. We aimed to identify risk factors of anemia using a Bayesian ... -
Are pro-inflammatory markers associated with psychological distress in a cross-sectional study of healthy adolescents 15–17 years of age? The Fit Futures study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-15)Background - Inflammatory markers have been associated with depression and anxiety disorder in adolescents. Less is known about the association between inflammation and subclinical symptoms in the form of psychological distress. We investigated prevalence of psychological distress and examined the associations between common pro-inflammatory markers and psychological distress in an adolescent ... -
Is amalgam removal in patients with medically unexplained physical symptoms cost-effective? A prospective cohort and modelling study in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-29)There are many patients in general practice with health complaints that cannot be medically explained. Some of these patients attribute their health complaints to dental amalgam restorations. This study examined the cost-effectiveness of the removal of amalgam restorations in patients with medically unexplained physical symptoms (MUPS) attributed to amalgam fillings compared to usual care, based ... -
Association between cannabis use and physical health problems in Norwegian adolescents: a cross-sectional study from the youth survey Ungdata
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-06)Background - Cannabis use is increasing among young Norwegians and several studies show a high incidence of common physical health problems. An association has previously been found between cannabis use and mental health problems. Since physical and mental health problems often co-occur, the aim of this study is to explore the relationship between cannabis use and physical health problems.<p> <p>Methods ... -
Mixing up contrastive learning: Self-supervised representation learning for time series
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-14)The lack of labeled data is a key challenge for learning useful representation from time series data. However, an unsupervised representation framework that is capable of producing high quality representations could be of great value. It is key to enabling transfer learning, which is especially beneficial for medical applications, where there is an abundance of data but labeling is costly and time ... -
Social media, physical activity and autism: better or bitter together? A scoping review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-22)This review provides an overview of the existing research on social media, autism, and physical activity. We searched for publications on PubMed, PsycInfo, Embase, Education source, ERIC, IEEE Xplore, and the proceedings from conferences on health informatics and autism. Eight studies were included in this review. Studies reported mixed results on the link between social media, physical activity, ...