Venous thromboembolism is the third common cardiovascular disease and is composed of two entities, deep vein thrombosis (DVT) and its potential fatal form, pulmonary embolism (PE). While PE is observed in~ 40% of patients with documented DVT, there is limited biomarkers that can help identifying patients at high PE risk. To fll this need, we implemented a two hidden-layers artifcial neural ...

In this article, we propose a novelteacher–student-based label propagation deep semisupervised learning (TSLP-SSL) method for sea ice classification based on Sentinel-1 synthetic aperture radar data. For sea ice classification, labeling the data precisely is very time consuming and requires expert knowledge. Our method efficiently learns sea ice characteristics from a limited number of labeled samples ...

Advances in molecular profiling have opened up the possibility to map the expression of genes in cells, tissues, and organs in the human body. Here, we combined single-cell transcriptomics analysis with spatial antibodybased protein profiling to create a high-resolution single–cell type map of human tissues. An open access atlas has been launched to allow researchers to explore the expression of ...

Rapid Arctic warming, manifested as thawing permafrost, loss of coastal sea ice, sea level rise, and climate-related extreme events, is particularly challenging for Indigenous people relying on wild food to sustain their livelihood and culture. The adoption of new technologies could provide specific capabilities to confront vulnerabilities associated with fishing and hunting activities, but it could ...

Energy Systems Modelling is growing in relevance on providing insights and strategies to plan a carbon-neutral future. The implementation of an effective energy transition plan faces multiple challenges, spanning from the integration of the operations of different energy carriers and sectors to the consideration of multiple spatial and temporal resolutions. In this review, we outline these challenges ...

Capsule: The number of breeding pairs of Europe’s largest Arctic Skua Stercorarius parasiticus colony at Slettnes, Norway, showed a dramatic decline of at least 50% over two decades, with food shortage in four years and increasing predation by Red Fox Vulpes vulpes leading to total breeding failure in five out of six recent study years.<p> Aims: To document the decline of Europe’s largest Arctic ...

Natural regeneration after anthropogenic disturbance is slow in the tundra biome, but assisted regeneration can help speed up this process. A tracked off-road vehicle damaged a High Arctic dwarf shrub heath in Svalbard in May 2009, drastically reducing the vegetation cover, soil seed banks, and incoming seed rain. We assisted regeneration the following year using six different revegetation treatments ...

Agglomeration of charged ice and dust particles in the mesosphere and lower thermosphere is studied using a classical electrostatic approach, which is extended to capture the induced polarisation of surface charge. Collision outcomes are predicted whilst varying the particle size, charge, dielectric constant, relative kinetic energy, collision geometry and the coefficient of restitution. In ...

Background<p> <p>There is a substantial gap in our knowledge about family correlates of child emotional and behavioral problems in low- and middle-income countries (LMIC). The present study contributes to filling this gap by examining such correlates in a larger population study in Nepal.<p> Methods<p> <p>Our study is a cross-sectional, observational study among 3840 Nepali children aged 6–18 ...

LTX-315 is a nonameric oncolytic peptide in early clinical development for the treatment of solid malignancies. Preclinical and clinical evidence indicates that the anticancer properties of LTX-315 originate not only from its ability to selectively kill cancer cells, but also from its capacity to promote tumortargeting immune responses. Here, we investigated the therapeutic activity and immunological ...