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Structure/function studies of the NAD<sup>+</sup>-dependent DNA ligase from the poly-extremophile Deinococcus radiodurans reveal importance of the BRCT domain for DNA binding
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-15)Bacterial NAD<sup>+</sup>-dependent DNA ligases (LigAs) are enzymes involved in replication, recombination, and DNA-repair processes by catalyzing the formation of phosphodiester bonds in the backbone of DNA. These multidomain proteins exhibit four modular domains, that are highly conserved across species, with the BRCT (breast cancer type 1 C-terminus) domain on the C-terminus of the enzyme. In ... -
UN human rights mechanisms in prevention of atrocity crimes: the context of mass atrocities in Ukraine
(Mastergradsoppgave; Master thesis, 2023-11-06)There has been limited examination of the current and potential capacity of the UN human rights mechanisms to effectively engage in preventive measures. The international community, mainly through the UN Security Council, focuses on peaceful conflict resolution, mediation and political interventions, narrowing the scope of atrocity prevention to security, diplomacy and politics. However, by reassessing ... -
Human Rights in Neoliberal Era: A Case Study of Georgia
(Mastergradsoppgave; Master thesis, 2023-11-01)Neoliberalism, characterised by free-market reforms, privatisation of public services and assets, prioritisation of private property rights, and limited government interference, has shaped the "neoliberal age." Critics argue that these policies have contributed to social inequality, poverty, and human rights violations. This research analyses the challenges neoliberal policies present to human rights ... -
Who deserves international protection in Europe? A critical analysis of the unequal treatment given to Convention refugees and beneficiaries of subsidiary protection in the European Union
(Mastergradsoppgave; Master thesis, 2023-11-01)The aim of this dissertation is to investigate the establishment of the Common European Asylum System (CEAS) and its successive reformulations, focusing on the EU policy on standards for the qualification of third-country nationals or stateless persons as refugees or beneficiaries of subsidiary protection. It analyses how hierarchies are constructed for the different policy target groups and how ... -
Relasjonsledelse. En studie av betydningen av leder – medarbeiderrelasjonen
(Master thesis; Mastergradsoppgave, 2023-12-01)I dette forskningsprosjektet har vi søkelys på relasjonen mellom leder og medarbeider. Vi tilbringer store deler av dagen på jobb, og det er viktig å føle at man har en god relasjon og føler trygghet til sin leder. Det er dessverre ikke slik for alle, noe som kan resultere i både turnover, sykemeldinger og konflikter. Dette er verken bedriften eller den enkelte medarbeider tjent med. Formålet ... -
European Union Governance Response to Corporate Social Responsibility and the French Case Study
(Master thesis; Mastergradsoppgave, 2023-11-01)This dissertation explores the European Union (EU) strategy on corporate responsibility in relation to sustainability reports and due diligence processes in human rights. The focus is on the French position in the area, as it was the first member state to legislate on the duty of vigilance. The aim is to examine the interaction with the EU and the member states in this issue-area using France as a ... -
Role of the lactate receptor HCAR1 as part of neural adaptations to hypoxia in hooded seals (Cystophora cristata)
(Master thesis; Mastergradsoppgave, 2023-11-15)To maintain normal neuronal function, the mammalian brain requires a constant supply of energy. The deep-diving hooded seal (<i>Cystophora cristata</i>) brain exhibits remarkable tolerance to extreme hypoxia, presumably involving a reduction in brain activity to lower energy demand. Thus, some neurons, circuits or even regions in the seal’s brain presumably display a neural protective shutdown ... -
Factors Associated with Peer Victimization Among Brazilian Low-Income Adolescents
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-16)Exposure to peer aggression and bullying victimization are both expressions of peer victimization but distinct constructs among adolescents. This study examined the potential associations between peer victimization and individual/family/peer factors and assessed whether the factors associated with peer aggression differed from those related to bullying victimization. This cross-sectional study, ... -
What's with the boys? Lower birth weight in boys from HPA-1a alloimmunized pregnancies – New insights from a large prospective screening study in Poland
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-07)Fetomaternal incompatibility in human platelet antigens (HPAs) can cause maternal alloimmunization, which in turn may lead to thrombocytopenia with or without intracranial hemorrhage (ICH) in the fetus or newborn. Retrospective studies suggest that boys from alloimmunized mothers may have higher risk of ICH and lower birth weight than girls. The objective of this study was to assess how maternal ... -
Discriminative multimodal learning via conditional priors in generative models
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-02)Deep generative models with latent variables have been used lately to learn joint representations and generative processes from multi-modal data, which depict an object from different viewpoints. These two learning mechanisms can, however, conflict with each other and representations can fail to embed information on the data modalities. This research studies the realistic scenario in which all ... -
Human-environment interactions in the Mesolithic – The case of site Paliwodzizna 29, a lakeside site in central Poland
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-10)Human-environmental relations before agriculture can be revealed at archaeological sites through multi-method palaeoenvironmental studies, particularly at sites which have both dryland and wetland areas. Paliwodzizna 29 is such as site, being a series of pits and hearths at the edge of Lake Grodno in Central Poland. A combination of faunal analysis, lithostratigraphy, pollen, diaspores, charcoal and ... -
Security of Supply: A National or European Competence?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-16)Security of supply refers to governmental policies that aim to secure the availability of critical products at all times. The COVID-19 pandemic brought to fore the importance of such policies, as suddenly there was an overwhelming need for critical medical supplies that the markets were not able to fulfil. Following the pandemic, the EU has started to construct its own security of supply policy, ... -
A study of self-perceived change in CBT competence among Norwegian therapists undertaking a 2-year CBT training for working with young people
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-17)The rising prevalence of mental illness among youth has underscored the critical need for proficient therapists trained in effective methods for treating prevalent mental disorders. As mental health services grapple with resource constraints, the demand for shorter training programs has increased. This study aimed to investigate whether therapist competence improves continuously over a two-year ... -
Local Oxidation States in {FeNO}<sup>6-8</sup> Porphyrins: Insights from DMRG/CASSCF-CASPT2 Calculations
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-27)A first DMRG/CASSCF–CASPT2 study of a series of paradigmatic {FeNO}<sup>6</sup>, {FeNO}<sup>7</sup>, and {FeNO}<sup>8</sup> heme–nitrosyl complexes has led to substantial new insight as well as uncovered key shortcomings of the DFT approach. By virtue of its balanced treatment of static and dynamic correlation, the calculations have provided some of the most authoritative information available to ... -
Cavity-Free Continuum Solvation: Implementation and Parametrization in a Multiwavelet Framework
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-18)We present a multiwavelet-based implementation of a quantum/classical polarizable continuum model. The solvent model uses a diffuse solute–solvent boundary and a position-dependent permittivity, lifting the sharp-boundary assumption underlying many existing continuum solvation models. We are able to include both surface and volume polarization effects in the quantum/classical coupling, with guaranteed ... -
A Theoretical Search for Stable Terminal Carbides
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-20)xploratory scalar-relativistic density functional theory (B3LYP*-D3/ZORA-STO-TZ2P) calculations have been used to examine the stability and bonding of pseudotetrahedral Group 8 (Fe, Ru, and Os) and Group 9 (Co, Rh, and Ir) terminal carbide complexes with dδ4 ground states and tripodal tris(N-heterocyclic-carbene) supporting ligands. The calculations predict relatively low adiabatic ionization ... -
Sub-ppm Methane Detection with Mid-Infrared Slot Waveguides
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-21)Hybrid integration of photonic chips with electronic and micromechanical circuits is projected to bring about miniature, but still highly accurate and reliable, laser spectroscopic sensors for both climate research and industrial applications. However, the sensitivity of chip-scale devices has been limited by immature and lossy photonic waveguides, weak light–analyte interaction, and etalon effects ... -
Machine learning assisted multifrequency AFM: Force model prediction
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-05)Multifrequency atomic force microscopy (AFM) enhances resolving power, provides extra contrast channels, and is equipped with a formalism to quantify material properties pixel by pixel. On the other hand, multifrequency AFM lacks the ability to extract and examine the profile to validate a given force model while scanning. We propose exploiting data-driven algorithms, i.e., machine learning packages, ... -
When Modality and Tense Meet. The Future Marker budet ‘will’ in Impersonal Constructions with the Modal Adverb možno ‘be possible’
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-08)This paper examines Russian impersonal constructions with the modal word možno ‘can, be possible’ with and without the future copula budet ‘will be,’ i.e., možno + budet + inf and možno + inf. My contribution can be summarized as follows. First, corpus-based evidence reveals that možno + inf constructions are vastly more frequent than constructions with copula. Second, the meaning of constructions ... -
Quantifying short-term changes in snow strength due to increasing liquid water content above hydraulic barriers
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-31)The rapid weakening of snow layers that accumulate infiltrating liquid water is a well-known, but poorly quantified, mechanism for wet-snow slab avalanche formation. Therefore, quantifying this mechanical process is a crucial part of forecasting these snow avalanches accurately. Currently, studies do not agree on how snow strength should change as a function of volumetric liquid water content ( ) ...