Background:<br> Treatment of childhood obesity is important in preventing development of obesity-related diseases later in life. This systematic review evaluates the effect of multicomponent lifestyle interventions for children and adolescents from 2 to 18 years. <br>Methods and Results:<br> We performed systematic searches in nine databases. Thirty-nine studies met the criteria for meta-analyses. ...

Prosjektet «Multifaktorielle sykdommer i norsk lakseoppdrett» er utført i et samarbeid mellom Nofima, Veterinærinstituttet, AquaGen AS og Patogen AS. Hovedmålet for prosjektet var å øke kunnskapen om utviklingen av multifaktorielle sykdommer ved å vurdere effekten av ulike variabler og deres interaksjon. Effekten av ulike variabler (genetisk resistens mot IPN, IPNV bærer status, IPNV reaktivering ...

From the earliest months of life, infants prefer listening to and learn better from infant-directed speech (IDS) compared with adult-directed speech (ADS). Yet IDS differs within communities, across languages, and across cultures, both in form and in prevalence. This large-scale, multisite study used the diversity of bilingual infant experiences to explore the impact of different types of linguistic ...

The Chlamydia trachomatis incidence rate in Finnmark, the most northern and sparsely populated county in Norway, has been twice the national average. This population based cross-sectional study among Finnmark high school students had the following aims: i) to examine distribution of multilocus sequence types (STs) of C. trachomatis in a previously unmapped area, ii) to compare chlamydia genetic ...

Liver sinusoidal endothelial cells (LSECs) act as a filter between blood and the hepatocytes. LSECs are highly fenestrated cells; they contain transcellular pores with diameters between 50 to 200 nm. The small sizes of the fenestrae have so far prohibited any functional analysis with standard and advanced light microscopy techniques. Only the advent of super-resolution optical fluorescence microscopy ...

Succinate is an essential intermediate of the tricarboxylic acid cycle that exerts pleiotropic roles beyond metabolism in both physiological and pathological conditions. Recent evidence obtained in mouse models shows its essential role regulating blood cell function through various mechanisms that include pseudohypoxia responses by hypoxiainducible factor-1α activation, post-translational modifications ...

Background: This is a response to Conti et al.’s article, “Listening in the dark: why we need stories of people living with severe and enduring anorexia nervosa” (published in JED, 2016), and its call for relational metaphors and a rela tional approach to supplement the traditional medical/psychological diagnostic language used to describe the life experiences and complex emotions of people ...

<p><i>Background:</i> Multiple sclerosis (MS) is a severe chronic inflammatory disease in the central nervous system, mainly affecting young adults. The prevalence varies between different parts of the world, but the general rule is that it increases with increasing latitude. Studies on comorbid conditions in MS are limited, but this topic have gained increasing interest. <p><i>Aims:</i> To describe ...

Previous analyses of the Atlantic cod genome showed unique combinations of lacking and expanded number of genes for the immune system. The present study examined lysozyme activity, lysozyme gene distribution and expression in cod. Enzymatic assays employing specific bacterial lysozyme inhibitors provided evidence for presence of g-Type, but unexpectedly not for c-Type lysozyme activity. Database ...

The liver as the largest organ in the human body is composed of a complex macroscopic and microscopic architecture that supports its indispensable function to maintain physiological homeostasis. Optical imaging of the human liver is particularly challenging because of the need to cover length scales across 7 orders of magnitude (from the centimeter scale to the nanometer scale) in order to fully ...