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norskBlar i tittel Doktorgradsavhandlinger (Helsefak)
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Wound healing in diabetes. An intervention study in db/db mice
(Doctoral thesis; Doktorgradsavhandling, 2017-06-09)The prevalence of diabetes is increasing globally. Certain microvascular and macrovascular complications such as cardiovascular disease, retinopathy, nephropathy, neuropathy, and impaired wound healing are associated with the disease. Prolonged exposure to hyperglycaemia plays an important role in their development. Glucose reacts with macromolecules including proteins, lipoproteins, and nucleic ... -
Wuthering heights: Outcomes from pancreatic surgery and trends in treatment of pancreatic ductal adenocarcinoma in Norway in a post-centralization era
(Doctoral thesis; Doktorgradsavhandling, 2021-10-22)<p><i>Aim:</i> The main aim of this thesis was to explore the contemporary outcomes of pancreatic surgery and treatment of pancreatic ductal adenocarcinoma in Norway seen in light of the centralization process and the volume-outcome relationship. <p><i>Methods:</i> We analysed three complete national patient cohorts using prospectively gathered data from national medical quality registries. The ... -
Young adults and seafood : using the voice of consumers to develop new seafood product concepts aimed at increasing consumption
(Doctoral thesis; Doktorgradsavhandling, 2010-09-24)Young adults do not eat seafood frequently enough because they lack knowledge about the preparation of a quick and easy meal with seafood. One of the ways to improve this situation is to offer young adults a product which is based on their needs and helps them to eat seafood more frequently. The first survey study showed a positive association between health involvement, attitudes towards seafood ... -
Young children with problem behaviour in school settings: Evaluation of the Incredible Years Teacher Classroom Management program in a Norwegian regular school setting
(Doctoral thesis; Doktorgradsavhandling, 2019-08-30)<i>Background</i>: Children in schools, who struggle behaviourally, socially, or emotionally, are less likely to benefit from academic instruction. In regular school settings, where a large numbers of students can be reached, teachers are important and natural implementers with the potential to influence mental health outcomes in all students. Examining the impact of the Incredible Years Teacher ... -
Zinc binding and chelating compounds as inhibitors of bacterial metalloproteases and human matrix metalloproteases
(Doctoral thesis; Doktorgradsavhandling, 2023-10-13)Bacterial multi-drug resistance is a major health problem worldwide. Inhibition of bacterial virulence is suggested to be a promising strategy in the development of new antibacterial drugs. The present work has focused on identifying new inhibitors of the bacterial virulence factors thermolysin (TLN), pseudolysin (PLN, LasB) and aureolysin (ALN), which are all zinc metalloproteases (MPs) using enzyme ...
