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  • Childhood violence and mental health among indigenous Sami and non-Sami populations in Norway: a SAMINOR 2 questionnaire study 

    Eriksen, Astrid; Hansen, Ketil Lenert; Schei, Berit; Sørlie, Tore; Stigum, Hein; Bjertness, Espen; Javo, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-16)
    The main objectives of this study were to investigate the association between childhood violence and psychological distress and post-traumatic stress symptoms (PTS) among Sami and non-Sami adults, and to explore a possible mediating effect of childhood violence on any ethnic differences in mental health. This study is part of a larger questionnaire survey on health and living conditions in Mid- and ...
  • Genetic variation in the ADIPOQ gene, adiponectin concentrations and risk of colorectal cancer: a Mendelian Randomization analysis using data from three large cohort studies 

    Nimptsch, Katharina; Song, Mingyang; Aleksandrova, Krasimira; Katsoulis, Michail; Freisling, Heinz; Jenab, Mazda; Gunter, Marc J.; Tsilidis, Konstantinos K.; Weiderpass, Elisabete; Bueno-De-Mesquita, Hendrik Bastiaan; Chong, Dawn Q.; Jensen, Majken K.; Wu, Chunsen; Overvad, Kim; Kühn, Tilman; Barrdahl, Myrto; Melander, Olle; Jirström, Karin; Peeters, Petra H.; Sieri, Sabina; Panico, Salvatore; Cross, Amanda J.; Riboli, Elio; van Guelpen, Bethany; Myte, Robin; Huerta, José María; Rodriguez-Barranco, Miguel; Quirós, José Ramón; Dorronsoro, Miren; Tjønneland, Anne; Olsen, Anja; Travis, Ruth; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Severi, Gianluca; Bonet, Catalina; Palli, Domenico; Janke, Jürgen; Lee, Young-Ae; Boeing, Heiner; Giovannucci, Edward L.; Ogino, Shuji; Fuchs, Charles S.; Rimm, Eric; Wu, Kana; Chan, Andrew T.; Pischon, Tobias (Journal article; Tidsskriftartikkel; Peer reviewed; Preprint, 2017-05-26)
    Higher levels of circulating adiponectin have been related to lower risk of colorectal cancer in several prospective cohort studies, but it remains unclear whether this association may be causal. We aimed to improve causal inference in a Mendelian Randomization meta-analysis using nested case–control studies of the European Prospective Investigation into Cancer and Nutrition (EPIC, 623 cases, 623 ...
  • The peer effect on pain tolerance 

    Engebretsen, Solveig; Frigessi, Arnoldo; Engø-Monsen, Kenth; Furberg, Anne-Sofie; Stubhaug, Audun; De Blasio, Birgitte Freiesleben; Nielsen, Christopher Sivert (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-19)
    Background and aims:<br> Twin studies have found that approximately half of the variance in pain tolerance can be explained by genetic factors, while shared family environment has a negligible effect. Hence, a large proportion of the variance in pain tolerance is explained by the (non-shared) unique environment. The social environment beyond the family is a potential candidate for explaining some ...
  • Dietary flavonoid intake and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) cohort 

    Zamora-Ros, Raul; Barupal, Dinesh Kumar; Rothwell, Joseph A.; Jenab, Mazda; Fedirko, Veronika; Romieu, Isabelle; Aleksandrova, Krasimira; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Affret, Aurélie; His, Mathilde; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kühn, Tilman; Boeing, Heiner; Trichopoulou, Antonia; Naska, Androniki; Kritikou, Maria; Saieva, Calogero; Agnoli, Claudia; Santucci de Magistris, Maria; Tumino, Rosario; Fasanelli, Francesca; Weiderpass, Elisabete; Skeie, Guri; Merino, Susana; Jakszyn, Paula; Sánchez, María-José; Dorronsoro, Miren; Navarro, Carmen; Ardanaz, Eva; Sonestedt, Emily; Ericson, Ulrika; Maria Nilsson, Lena; Bodén, Stina; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Perez-Cornago, Aurora; Wareham, Nicholas J.; Khaw, Kay-Thee; Freisling, Heinz; Cross, Amanda J.; Riboli, Elio; Scalbert, Augustin (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-22)
    Flavonoids have been shown to inhibit colon cancer cell proliferation in vitro and protect against colorectal carcinogenesis in animal models. However, epidemiological evidence on the potential role of flavonoid intake in colorectal cancer (CRC) development remains sparse and inconsistent. We evaluated the association between dietary intakes of total flavonoids and their subclasses and risk of ...
  • Burden of hip fracture using disability-adjusted life-years: a pooled analysis of prospective cohorts in the CHANCES consortium 

    Papadimitriou, Nikos; Tsilidis, Konstantinos K.; Orfanos, Philippos; Benetou, Vassiliki; Ntzani, Evangelia E.; Soerjomataram, Isabelle; Künn-Nelen, Annemarie; Pettersson-Kymmer, Ulrika; Eriksson, Sture; Brenner, Hermann; Schöttker, Ben; Saum, Kai-Uwe; Holleczek, Bernd; Grodstein, Francine D.; Feskanich, Diane; Orsini, Nicola; Wolk, Alicja; Bellavia, Andrea; Wilsgaard, Tom; Jørgensen, Lone; Boffetta, Paolo; Trichopoulos, Dimitrios; Trichopoulou, Antonia (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-11)
    <p><i>Background</i>: No studies have estimated disability-adjusted life-years (DALYs) lost due to hip fractures using real-life follow-up cohort data. We aimed to quantify the burden of disease due to incident hip fracture using DALYs in prospective cohorts in the CHANCES consortium, and to calculate population attributable fractions based on DALYs for specific risk factors.</p> <p><i>Methods</i>: ...
  • A prospective evaluation of plasma phospholipid fatty acids and breast cancer risk in the EPIC study 

    Chajès, Véronique; Assi, Nada; Biessy, Carine; Ferrari, P.; Rinaldi, Sabina; Slimani, Nadia; Lenoir, GM; Baglietto, L; His, Mathilde; Boutron-Ruault, M.C.; Trichopoulou, A; Lagiou, P.; Katsoulis, M; Kaaks, R.; Kuhn, T.; Panico, S.; Pala, V; Masala, G; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, P.H.; van Gils, Carla; Hjartåker, Anette; Olsen, Karina Standahl; Borgund Barnung, Runa; Barricarte, A; Redondo-Sánchez, Daniel; Menéndez, V; Amiano, P.; Wennberg, Maria; Key, T.; Khaw, K.T.; Merritt, M.A.; Riboli, E.; Gunter, M.J.; Romieu, I. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-18)
    <p><i>Background</i>: Intakes of specific fatty acids have been postulated to impact breast cancer risk but epidemiological data based on dietary questionnaires remain conflicting.</p> <p><i>Materials and methods</i>: We assessed the association between plasma phospholipid fatty acids and breast cancer risk in a case–control study nested within the European Prospective Investigation into Cancer ...
  • Testing alternative regression models to predict utilities: mapping the QLQ-C30 onto the EQ-5D-5L and the SF-6D 

    Lamu, Admassu Nadew; Olsen, Jan Abel (Journal article; Tidsskriftartikkel; Peer reviewed; Preprint, 2018-09-01)
    <p><i>Purpose</i>: The purpose of the study was to compare alternative statistical techniques to find the best approach for converting QLQ-C30 scores onto EQ-5D-5L and SF-6D utilities, and to estimate the mapping algorithms that best predict these health state utilities.</p> <p><i>Methods</i>: 772 cancer patients described their health along the cancer-specific instrument (QLQ-C30) and two generic ...
  • Pooled analysis of active cigarette smoking and invasive breast cancer risk in 14 cohort studies 

    Gaudet, Mia M.; Carter, Brian D.; Brinton, Louise A.; Falk, Roni T.; Gram, Inger Torhild; Luo, Juhua; Milne, Roger L.; Nyante, Sarah J.; Weiderpass, Elisabete; Freeman, Laura E. Beane; Sandler, Dale P.; Robien, Kim; Anderson, Kristin E.; Giles, Graham G.; Chen, Wendy Y.; Feskanich, Diane; Braaten, Tonje; Isaacs, Claudine; Butler, Lesley M.; Koh, Woon-Puay; Wolk, Alicja; Adami, Hans Olov; White, Emily; Margolis, Karen L.; Thun, Michael J.; Gapstur, Susan M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-19)
    <p><i>Background</i>: The 2014 US Surgeon General’s report noted research gaps necessary to determine a causal relationship between active cigarette smoking and invasive breast cancer risk, including the role of alcohol consumption, timing of exposure, modification by menopausal status and heterogeneity by oestrogen receptor (ER) status.</p> <p><i>Methods</i>: To address these issues, we pooled ...
  • Probing the differential tissue distribution and bioaccumulation behavior of per- and polyfluoroalkyl substances of varying chain-lengths, isomeric structures and functional groups in crucian carp 

    Shi, Yali; Vestergren, Robin; Nøst, Therese Haugdahl; Zhou, Zhen; Cai, Yaqi (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-03)
    Understanding the bioaccumulation mechanisms of per- and polyfluoroalkyl substances (PFASs) across different chain-lengths, isomers and functional groups represents a monumental scientific challenge with implications for chemical regulation. Here, we investigate how the differential tissue distribution and bioaccumulation behavior of 25 PFASs in crucian carp from two field sites impacted by point ...
  • Prediagnostic calcium intake and lung cancer survival: A pooled analysis of 12 cohort studies 

    Yu, Danxia; Takata, Yumie; Smith-Warner, Stephanie A.; Blot, William; Sawada, Norie; White, Emily; Freedman, Neal; Robien, Kim; Giovannucci, Edward; Zhang, Xuehong; Park, Yikyung; Gao, Yu-Tang; Chlebowski, Rowan T.; Langhammer, Arnulf; Yang, Gong; Severi, Gianluca; Manjer, Jonas; Khaw, Kay-Tee; Weiderpass, Elisabete; Liao, Linda M.; Caporaso, Neil; Krokstad, Steinar; Hveem, Kristian; Sinha, Rashmi; Ziegler, Regina; Tsugane, Shoichiro; Xiang, Yong-Bing; Johansson, Mattias; Zheng, Wei; Shu, Xiao-Ou (Journal article; Tidsskriftartikkel; Peer reviewed; Preprint, 2017-03-06)
    <p><i>Background</i>: Lung cancer is the leading cause of cancer death. Little is known about whether prediagnostic nutritional factors may affect survival. We examined the associations of prediagnostic calcium intake from foods and/or supplements with lung cancer survival.</p> <p><i>Methods</i>: The present analysis included 23,882 incident, primary lung cancer patients from 12 prospective cohort ...
  • Biomarkers of folate and vitamin B12 and breast cancer risk: report from the EPIC cohort 

    Matejcic, Marco; De Batlle, Jordi; Ricci, Cristian; Biessy, Carine; Perrier, Flavie; Huybrechts, Inge; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Cadeau, Claire; His, Mathilde; Cox, David G.; Boeing, Heiner; Fortner, Renée Turzanski; Kaaks, Rudolf; Lagiou, Pagona; Trichopoulou, Antonia; Benetou, Vassiliki; Tumino, Rosario; Panico, Salvatore; Sieri, Sabina; Palli, Domenico; Ricceri, Fulvio; Bueno-De-Mesquita, Hendrik Bastiaan; Skeie, Guri; Amiano, Pilar; Sánchez, María-José; Chirlaque, María-Dolores; Barricarte, Aurelio; Quirós, José Ramón; Buckland, Genevieve; van Gils, Carla H.; Peeters, Petra H.; Key, Timothy J.; Riboli, Elio; Gylling, Björn; Zeleniuch-Jacquotte, Anne; Gunter, Mark J.; Romieu, Isabelle; Chajès, Véronique (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-01)
    Epidemiological studies have reported inconsistent findings for the association between B vitamins and breast cancer (BC) risk. We investigated the relationship between biomarkers of folate and vitamin B12 and the risk of BC in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Plasma concentrations of folate and vitamin B12 were determined in 2,491 BC cases individually ...
  • DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk 

    Baglietto, Laura; Ponzi, Erica; Haycock, Philip; Hodge, Allison; Bianca Assumma, Manuela; Jung, Chol-Hee; Chung, Jessica; Fasanelli, Francesca; Guida, Florence; Campanella, Gianluca; Chadeau-Hyam, Marc; Grankvist, Kjell; Johansson, Mikael; Ala, Ugo; Provero, Paolo; Wong, Ee Ming; Joo, Jihoon; English, Dallas R.; Kazmi, Nabila; Lund, Eiliv; Faltus, Christian; Risch, Angela; Barrdahl, Myrto; Sandanger, Torkjel M; Southey, Melissa C.; Giles, Graham G.; Johansson, Mattias; Vineis, Paolo; Polidoro, Silvia; Relton, Caroline L.; Severi, Gianluca (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-15)
    DNA methylation changes are associated with cigarette smoking. We used the Illumina Infinium HumanMethylation450 array to determine whether methylation in DNA from pre‐diagnostic, peripheral blood samples is associated with lung cancer risk. We used a case‐control study nested within the EPIC‐Italy cohort and a study within the MCCS cohort as discovery sets (a total of 552 case‐control pairs). We ...
  • Using Fitness Trackers and Smartwatches to Measure Physical Activity in Research: Analysis of Consumer Wrist-Worn Wearables 

    Henriksen, André; Mikalsen, Martin Haugen; Woldaregay, Ashenafi Zebene; Muzny, Miroslav; Hartvigsen, Gunnar; Hopstock, Laila Arnesdatter; Grimsgaard, Sameline (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-22)
    Background: New fitness trackers and smartwatches are released to the consumer market every year. These devices are equipped with different sensors, algorithms, and accompanying mobile apps. With recent advances in mobile sensor technology, privately collected physical activity data can be used as an addition to existing methods for health data collection in research. Furthermore, data collected ...
  • Controversies about cervical cancer screening: A qualitative study of Roma women's (non)participation in cervical cancer screening in Romania 

    Andreassen, Trude; Weiderpass, Elisabete; Nicula, Florian; Suteu, Ofelia; Itu, Andreea; Bumbu, Minodora; Tincu, Aida; Ursin, Giske; Moen, Kåre (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-26)
    Romania has Europe's highest incidence and mortality of cervical cancer. While a free national cervical cancer-screening programme has been in operation since 2012, participation in the programme is low, particularly in minority populations. The aim of this study was to explore Roma women's (non)participation in the programme from women's own perspectives and those of healthcare providers and policy ...
  • Nut intake and 5-year changes in body weight and obesity risk in adults: results from the EPIC-PANACEA study 

    Freisling, Heinz; Noh, Hwayoung; Slimani, Nadia; Chajès, Véronique; May, Anne M.; Peeters, Petra H; Weiderpass, Elisabete; Cross, Amanda J.; Skeie, Guri; Jenab, Mazda; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Katzke, Verena A.; Kühn, Tilman; Steffen, Annika; Boeing, Heiner; Tjønneland, Anne; Kyrø, Cecilie; Hansen, Camilla P.; Overvad, Kim; Duell, Eric J.; Redondo-Sánchez, Daniel; Amiano, Pilar; Navarro, Carmen; Barricarte, Aurelio; Perez-Cornago, Aurora; Tsilidis, Konstantinos K.; Aune, Dagfinn; Ward, Heather; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Masala, Giovanna; Agnoli, Claudia; Berrino, Franco; Tumino, Rosario; Sacerdote, Carlotta; Mattiello, Amalia; Bueno-De-Mesquita, Hendrik Bastiaan; Ericson, Ulrika; Sonestedt, Emily; Winkvist, Anna; Braaten, Tonje; Romieu, Isabelle; Sabaté, Joan (Journal article; Tidsskriftartikkel; Peer reviewed; Preprint, 2017-07-21)
    <p><i>Purpose</i>: There is inconsistent evidence regarding the relationship between higher intake of nuts, being an energy-dense food, and weight gain. We investigated the relationship between nut intake and changes in weight over 5 years.</p> <p><i>Methods</i>: This study includes 373,293 men and women, 25–70 years old, recruited between 1992 and 2000 from 10 European countries in the European ...
  • Psychological abuse, substance abuse distress, dissatisfaction with friendships, and incident psychiatric problems 

    Sheikh, Mashhood Ahmed (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-06)
    <p><i>Objective</i>: The aim of this study was to assess the mediating role of dissatisfaction with friendships in adulthood in the associations between psychological abuse in childhood, substance abuse distress in childhood, and incident psychiatric problems (IPPs) in adulthood over 13 years of follow-up.</p> <p><i>Methods</i>: We used data collected from 1994 to 2008 within the framework of the ...
  • Gender specific association between the use of complementary and alternative medicine (CAM) and alcohol consumption and injuries caused by drinking in the sixth Tromsø study 

    Sivertsen, Kristina; Lukic, Marko; Kristoffersen, Agnete Egilsdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-13)
    <p><i>Background</i>: Alcohol is consumed almost worldwide and is the most widely used recreational drug in the world. Harmful use of alcohol is known to cause a large disease-, social- and economic burden on society. Only a few studies have examined the relationship between CAM use and alcohol consumption. To our knowledge there has been no such research in Norway. The aim of this study is to ...
  • Androgens are differentially associated with ovarian cancer subtypes in the Ovarian Cancer Cohort Consortium 

    Ose, Jennifer; Poole, Elizabeth M.; Schock, Helena; Lehtinen, Matti; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Visvanathan, Kala; Helzlsouer, Kathy; Buring, Julie E.; Lee, I-Min; Tjønneland, Anne; Dossus, Laure; Trichopoulou, Antonia; Masala, Giovanna; Onland-Moret, N. Charlotte; Weiderpass, Elisabete; Duell, Eric J.; Idahl, Annika; Travis, Ruth C.; Rinaldi, Sabina; Merritt, Melissa A.; Trabert, Britton; Wentzensen, Nicolas; Tworoger, Shelley S.; Kaaks, Rudolf; Fortner, Renée T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-05)
    Invasive epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy. The etiology of EOC remains elusive; however, experimental and epidemiologic data suggest a role for hormone-related exposures in ovarian carcinogenesis and risk factor differences by histologic phenotypes and developmental pathways. Research on pre-diagnosis androgen concentrations and EOC risk has yielded inconclusive ...
  • Disordered eating in Sami and non-Sami Norwegian populations: the SAMINOR 2 Clinical Survey 

    Kvaløy, Kirsti; Melhus, Marita; Silviken, Anne; Brustad, Magritt; Sørlie, Tore; Broderstad, Ann Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-10)
    <p><i>Objective</i>: The present study aimed to investigate disordered eating (DE) among Sami compared with non-Sami residing in northern Norway.</p> <p><i>Design</i>: In a cross-sectional design, stratified by sex and ethnicity, associations were tested between DE (Eating Disturbance Scale; EDS-5) and age, education level, BMI category, anxiety and depression, physical activity and consumption ...
  • ‘Not a film about my slackness’: Making sense of medically unexplained illness in youth using collaborative visual methods 

    Østbye, Silje Vagli; Kvamme, Maria Fredriksen; Wang, Catharina Elisabeth Arfwedson; Haavind, Hanne; Waage, Trond; Risør, Mette Bech (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-06)
    Persistent medically unexplained symptoms have debilitating consequences for adolescents, dramatically altering their social world and future aspirations. Few studies have focused on social and moral aspects of illness experience relevant to adolescents. In this study, the aim is to explore these aspects in depth by focusing on a single case and to address how young people attempt to create social ...

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