• The creation of long-lived HPA-1a specific T-cell clones 

      Roalsø, Marcus T.T. (Master thesis; Mastergradsoppgave, 2016-08-09)
      Neonatal alloimmune thrombocytopenia (NAIT) is a disease where the fetus or newborn experience pathological low levels of blood platelets. This is a potentially fatal condition. Antibodies produced by the mother, crossing the placental barrier, targeting the β3-integrins expressed on fetal platelets, drive the disease. The antibodies are initially produced by B-cells, which are dependent on T-cells ...