• Recombinant T-cell receptors from HPA-1a specific T-cells 

      Sætre, Thomas (Mastergradsoppgave; Master thesis, 2022-02-01)
      Fetal- and neonatal alloimmune thrombocytopenia is a condition that can cause hemorrhage and potential brain damage or death in neonates. It is most often a result of maternal alloantibodies specific for fetal Human Platelet antigen 1a (HPA-1a) that destroy fetal platelets. The recognition of the HPA-1a peptide-MHC complex by T-cells involve a peculiar form of T-cell receptor peptide-MHC ...