High-resolution optical nanoscopy of placental cells

Abstract

<i>Introduction</i>: The invention of fluorescence based super-resolution optical microscopy, commonly referred to as optical nanoscopy, has provided a glimpse of its future impacts on life science and medical care. Optical nanoscopy enables study of sub-cellular nanoscale biological systems in living cells, which in past was limited to electron microscopy (in fixed cells). Optical nanoscopy provide visualization of sub-cellular structures with an unprecedented optical resolution of 30-50 nm.