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dc.contributor.authorNeves, Carlos Gonzalo das
dc.contributor.authorJohansson Wensman, Jonas
dc.contributor.authorNymo, Ingebjørg Helena
dc.contributor.authorSkjerve, Eystein
dc.contributor.authorAlenius, Stefan
dc.contributor.authorTryland, Morten
dc.date.accessioned2020-01-22T10:00:59Z
dc.date.available2020-01-22T10:00:59Z
dc.date.issued2019-12-26
dc.description.abstractMembers of the Pestivirus genus (family <i>Flaviviridae</i>) cause severe and economically important diseases in livestock. Serological studies have revealed the presence of pestiviruses in different cervid species, including wild and semi-domesticated Eurasian tundra reindeer. In this retrospective study, serum samples collected between 2006 and 2008 from 3339 semi-domesticated Eurasian reindeer from Finnmark County, Norway, were tested for anti-pestivirus antibodies using an enzyme linked immunosorbent assay (ELISA) and a subset of these by virus neutralization test (VNT). A seroprevalence of 12.5% was found, varying from 0% to 45% among different herding districts, and 20% in western Finnmark, as compared to 1.7% in eastern Finnmark. Seroprevalence increased with age. Pestivirus-specific RNA was not detected in any of the 225 serum samples tested by real-time RT-PCR. Based on VNT results, using a panel of one bovine viral diarrhea virus (BVDV) strain and two border disease virus (BDV) strains, the virus is most likely a reindeer-specific pestivirus closely related to BDV. A characterization of the causative virus and its pathogenic impact on reindeer populations, as well as its potential to infect other domestic and wild ruminants, should be further investigateden_US
dc.identifier.citationNeves CGd, Johansson Wensman, Nymo IH, Skjerve E, Alenius S, Tryland M. Pestivirus Infections in Semi-Domesticated Eurasian Tundra Reindeer (Rangifer tarandus tarandus): A Retrospective Cross-Sectional Serological Study in Finnmark County, Norway.. Viruses. 2019;12(1)en_US
dc.identifier.cristinIDFRIDAID 1779260
dc.identifier.doi10.3390/v12010029
dc.identifier.issn1999-4915
dc.identifier.urihttps://hdl.handle.net/10037/17165
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.relation.journalViruses
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2019 The Author(s)en_US
dc.subjectVDP::Mathematics and natural science: 400::Zoology and botany: 480en_US
dc.subjectVDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480en_US
dc.titlePestivirus Infections in Semi-Domesticated Eurasian Tundra Reindeer (Rangifer tarandus tarandus): A Retrospective Cross-Sectional Serological Study in Finnmark County, Norway.en_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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