Blar i forfatter Mastergradsoppgaver i kjemi "Skagseth, Susann"
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Site-directed mutagenesis of the metallo-β-lactamase VIM-7 from the opportunistic human pathogenic bacteria Pseudomonas aeruginosa
Skagseth, Susann (Master thesis; Mastergradsoppgave, 2012-05-15)The metallo-β-lactamases (MBLs) are enzymes with the ability to hydrolyse the β-lactam antibiotics. The worldwide emergence of the antibiotic resistant MBLs poses an increasing clinical threat. The VIM enzymes are a growing family of carbapenemases with a wide geographic distribution in Europe, South America and the USA. The VIM-7, the first VIM enzyme to be discovered in the USA, is the most divergent ...