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dc.contributor.authorCooper, Rachel
dc.contributor.authorShkolnikov, Vladimir M.
dc.contributor.authorKudryavtsev, Alexander
dc.contributor.authorMalyutina, Sofia
dc.contributor.authorRyabikov, Andrew
dc.contributor.authorHopstock, Laila Arnesdatter
dc.contributor.authorJohansson, Jonas
dc.contributor.authorCook, Sarah Anne
dc.contributor.authorLeon, David
dc.contributor.authorStrand, Bjørn Heine
dc.date.accessioned2021-11-26T09:18:39Z
dc.date.available2021-11-26T09:18:39Z
dc.date.issued2021-10-03
dc.description.abstractBackground - Identifying individuals with low grip strength is an initial step in many operational definitions of sarcopenia. As evidence indicates that contemporaneous Russian populations may have lower mean levels of grip strength than other populations in northern Europe, we aimed to: compare grip strength in Russian and Norwegian populations by age and sex; investigate whether height, body mass index, education, smoking status, alcohol use and health status explain observed differences and; examine implications for case-finding low muscle strength.<p> <p>Methods - We used harmonized cross-sectional data on grip strength and covariates for participants aged 40–69 years from the Russian Know Your Heart study (KYH) (n = 3833) and the seventh survey of the Norwegian Tromsø Study (n = 5598). Maximum grip strength (kg) was assessed using the same protocol and device in both studies. Grip strength by age, sex and study was modelled using linear regression and between-study differences were predicted from these models. Sex-specific age-standardized differences in grip strength and in prevalence of low muscle strength were estimated using the European population standard of 2013.<p> <p>Results - Normal ranges of maximum grip strength in both studies combined were 33.8 to 67.0 kg in men and 18.7 to 40.1 kg in women. Mean grip strength was higher among Tromsø than KYH study participants and this difference did not vary markedly by age or sex. Adjustment for covariates, most notably height, attenuated between-study differences but these differences were still evident at younger ages. For example, estimated between-study differences in mean grip strength in fully adjusted models were 2.2 kg [95% confidence interval (CI) 1.4, 3.1] at 40 years and 1.0 kg (95% CI 0.5, 1.5) at 65 years in men (age × study interaction P = 0.09) and 1.1 kg (95% CI 0.4, 1.9) at age 40 years and −0.2 kg (95% CI −0.7, 0.3) at 65 years in women (age × study interaction P < 0.01).<p> <p>Conclusions - We found between-study differences in mean grip strength that are likely to translate into greater future risk of sarcopenia and poorer prospects of healthy ageing for Russian than Norwegian study participants. For example, the average Russian participant had a similar level of grip strength to a Norwegian participant 7 years older. Our findings suggest these differences may have their origins in childhood highlighting the need to consider interventions in early life to prevent sarcopenia.en_US
dc.identifier.citationCooper, Shkolnikov, Kudryavtsev, Malyutina, Ryabikov, Hopstock, Johansson, Cook, Leon, Strand. Between-study differences in grip strength: a comparison of Norwegian and Russian adults aged 40-69 years. Journal of Cachexia, Sarcopenia and Muscle. 2021en_US
dc.identifier.cristinIDFRIDAID 1944606
dc.identifier.doi10.1002/jcsm.12816
dc.identifier.issn2190-5991
dc.identifier.issn2190-6009
dc.identifier.urihttps://hdl.handle.net/10037/23174
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.journalJournal of Cachexia, Sarcopenia and Muscle
dc.relation.projectIDinfo:eu-repo/grantAgreement/RCN/?/?/Norway?/?/?/en_US
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801en_US
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en_US
dc.titleBetween-study differences in grip strength: a comparison of Norwegian and Russian adults aged 40-69 yearsen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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