Recent additions

  • Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy 

    Pandya, Abhilash D.; Jäger, Eliézer; Fam, Shahla Bagheri; Höcherl, Anita; Jäger, Alessandro; Sincari, Vladimir; Nyström, Bo; Štěpánek, Petr; Skotland, Tore; Sandvig, Kirsten; Hrubý, Martin; Mælandsmo, Gunhild M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-06)
    <i>Background</i>: Reactive oxygen species (ROS), such as hydrogen peroxide and superoxide, trigger biodegradation of polymer-based nanoparticles (NPs) bearing pinacol-type boronic ester groups. These NPs may selectively release their cargo, in this case paclitaxel (PTX), at the high levels of ROS present in the intracellular environment of inflamed tissues and most tumors.<p> <p><i>Purpose</i>: ...
  • Sannhetskommisjoner. Om institusjonalisert kunnskap, kritisk distanse og andre antropologiske utfordringer 

    Saugestad, Sidsel (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-20)
    Denne artikkelen ser på noen aspekter av en sannhetskommisjon som er oppnevnt i Norge. Den første delen skisserer bakgrunnen for oppnevnelsen og diskuterer de argumentene som ble fremlagt, supplert med sitater fra en avisdebatt. Den andre delen setter denne debatten inn i en bredere sammenheng av norsk-samiske relasjoner og gir noen eksempler på samisk kommunikasjon om rett til å være forskjellig. ...
  • Differential expression of the miR-17-92 cluster and miR-17 family in breast cancer according to tumor type; results from the Norwegian Women and Cancer (NOWAC) study 

    Moi, Line; Braaten, Tonje; Al-Shibli, Khalid; Lund, Eiliv; Rasmussen Busund, Lill-Tove (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-03)
    <i>Background</i> - MicroRNAs (miRNAs) are promising biomarkers due to their structural stability and distinct expression profile in various cancers. We wanted to explore the miRNA expression in benign breast tissue and breast cancer subgroups in the Norwegian Women and Cancer study.<p> <p><i>Methods</i> - Specimens and histopathological data from study participants in Northern Norway diagnosed ...
  • Allodia Winnertz from the Himalayas, with nine species new to science (Diptera, Mycetophilidae). 

    Magnussen, Trude; Søli, Geir Einar Ellefsen; Kjærandsen, Jostein (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-29)
    An extensive collection of fungus gnats from Nepal and Bhutan, deposited at Kyushu University Museum in Japan, has been examined and revealed nine species of <i>Allodia</i> Winnertz, 1864 new to science: <i>Allodia caligata</i> Magnussen, <b>sp. n.</b>, <i>A. dibolia</i> Magnussen, <b>sp. n.</b>, <i>A. shimai</i> Magnussen, <b>sp. n.</b>, <i>A. spathulata</i> Magnussen, <b>sp. n.</b>, <i>A. horologia</i> ...
  • Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival 

    Mathiesen, Randi Margit Ruud; Borgen, Elin; Renolen, Anne; Løkkevik, Erik; Nesland, Jahn M; Anker, Gun Birgitta; Østenstad, Bjørn; Lundgren, Steinar; Risberg, Terje; Mjaaland, Ingvil; Kvalheim, Gunnar; Lønning, Per Eystein; Naume, Bjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-08-14)
    <i>Introduction</i> - Presence of disseminated tumor cells (DTCs) in bone marrow (BM) and circulating tumor cells (CTC) in peripheral blood (PB) predicts reduced survival in early breast cancer. The aim of this study was to determine the presence of and alterations in DTC- and CTC-status in locally advanced breast cancer patients undergoing neoadjuvant chemotherapy (NACT) and to evaluate their ...
  • An integrated transcriptome analysis in T-cell acute lymphoblastic leukemia links DNA methylation subgroups to dysregulated TAL1 and ANTP homeobox gene expression 

    Haider, Zahra; larsson, Pär; Landfors, Mattias; Kohn, Linda; Schmiegelow, Kjeld; Flægstad, Trond; Kanerva, Jukka; Heyman, Mats; Hultdin, Magnus; Degerman, Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-21)
    Classification of pediatric T-cell acute lymphoblastic leukemia (T-ALL) patients into CIMP (CpG Island Methylator Phenotype) subgroups has the potential to improve current risk stratification. To investigate the biology behind these CIMP subgroups, diagnostic samples from Nordic pediatric T-ALL patients were characterized by genome-wide methylation arrays, followed by targeted exome sequencing, ...
  • Long-term effects on survival after a 1-year multifactorial vascular risk factor intervention after stroke or TIA: secondary analysis of a randomized controlled trial, a 7-year follow-up study 

    Hagberg, Guri; Fure, Brynjar; Sandset, Else Charlotte; Thommessen, Bente; Ihle-Hansen, Håkon; Øksengård, Anne Rita; Nygård, Ståle; Wyller, Torgeir Bruun; Ihle-Hansen, Hege (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-07)
    <p><i>Background - </i>Stroke and coronary heart disease share the same risk factors, and a multifactorial intervention after stroke may potentially result in the same reduction in cardiovascular mortality as seen after coronary events. We aimed to evaluate the effect on survival 7 years after a 1-year multifactorial risk factor intervention, and identify clinical predictors for long-term survival ...
  • La citation de données de recherche dans des publications en linguistique: L’histoire d’une initiative prise par la communauté scientifique 

    Andreassen, Helene N. (Conference object; Konferansebidrag, 2019-10-03)
    La création et la diffusion de la recherche reproductible reçoivent de plus en plus d’attention dans la discussion sur les meilleures pratiques de publication et d’enseignement. Un élément clé de ces pratiques constitue la citation appropriée des données de recherche. En 2017, un réseau de chercheurs, archivistes et bibliothécaires a fondé un groupe au sein de Research Data Alliance, Linguistics ...
  • Climatology of the mesopause relative density using a global distribution of meteor radars 

    Yi, Wen; Xue, Xianghui; Reid, Iain; Murphy, Damian J.; Hall, Chris; Tsutsumi, Masaki; Ning, Baiqi; Li, Guozhu; Vincent, Robert; Chen, Jinsong; Wu, Jianfei; Chen, Tingdi; Dou, Xiankang (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-06)
    The existing distribution of meteor radars located from high- to low-latitude regions provides a favorable temporal and spatial coverage for investigating the climatology of the global mesopause density. In this study, we report the climatology of the mesopause relative density estimated using multiyear observations from nine meteor radars, namely, the Davis Station (68.6∘ S, 77.9∘ E), Svalbard ...
  • A guided internet-delivered individually-tailored ACT-influenced cognitive behavioural intervention to improve psychosocial outcomes in breast cancer survivors (iNNOVBC): Study protocol 

    Mendes-Santos, Cristina; Weiderpass, Elisabete; Santana, Rui; Andersson, Gerhard (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-10)
    <p><i>Background - </i>Internet-delivered interventions can provide remarkable opportunities in addressing breast cancer survivors' unmet support care needs, as they present an effective strategy to improve care coordination and provide access to efficacious, cost-efficient and convenient survivorship care. Nevertheless, research focusing on improving survivors' psychosocial needs using internet-based ...
  • Hydroxyl radicals generated by hydrogen peroxide photolysis recondition biofilm-contaminated titanium surfaces for subsequent osteoblastic cell proliferation 

    Nakamura, Keisuke; Shirato, Midori; Tenkumo, Taichi; Kanno, Taro; Westerlund, Anna; Örtengren, Ulf Tore; Sasaki, Keiichi; Niwano, Yoshimi (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-18)
    Titanium dental implants have been successfully used for decades; however, some implants are affected by peri-implantitis due to bacterial infection, resulting in loss of supporting bone. This study aimed to evaluate the effect of an antimicrobial chemotherapy employing H<sub>2</sub>O<sub>2</sub> photolysis—developed to treat peri-implantitis—on biofilm-contaminated titanium surfaces in association ...
  • Representations of child welfare services in Norwegian, Danish and German newspapers 

    Schönfelder, Walter; Holmgaard, Sanne Bech (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-23)
    Child welfare services are often scrutinized in media reports, but few comparisons of how services are represented in different countries are available. The aim of this article is to assess whether systematic differences in the representation of child welfare services in Norwegian, Danish and German newspapers can be documented. A content analysis of major newspapers in each country revealed ...
  • Decompression alone versus decompression with instrumental fusion the NORDSTEN degenerative spondylolisthesis trial (NORDSTEN-DS); study protocol for a randomized controlled trial 

    Austevoll, Ivar Magne; Hermansen, Erland; Fagerland, Morten; Rekeland, Frode; Solberg, Tore; Storheim, Kjersti; Brox, Jens Ivar; Lønne, Greger; Indrekvam, Kari; Aaen, Jørn; Grundnes, Oliver; Hellum, Christian (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-05)
    <p><i>Background - </i>Fusion in addition to decompression has become the standard treatment for lumbar spinal stenosis with degenerative spondylolisthesis (DS). The evidence for performing fusion among these patients is conflicting and there is a need for further investigation through studies of high quality. The present protocol describes an ongoing study with the primary aim of comparing the ...
  • Overcoming clinician and parent ambivalence: General practitioners' support of children of parents with physical or mental illness and/or substance abuse 

    Hafting, Marit; Gullbrå, Frøydis; Anderssen, Norman; Rørtveit, Guri; Smith-Sivertsen, Tone; Doesum, Karin van (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-08)
    Children who are next of kin to parents with physical or mental illness and/or substance abuse need access to mental health support and several cost-effective interventions are available. Because most parents in the target group often consult general practitioners (GPs), GPs may have a crucial role in identifying burdened children and ensuring their follow-up. However, this important topic has ...
  • Clinical outcome after surgery for lumbar spinal stenosis in patients with insignificant lower extremity pain. A prospective cohort study from the Norwegian registry for spine surgery 

    Hermansen, Erland; Myklebust, Tor Åge; Austevoll, Ivar Magne; Rekeland, Frode; Solberg, Tore; Storheim, Kjersti; Grundnes, Oliver; Aaen, Jørn Ståle; Brox, Jens Ivar; Hellum, Christian; Indrekvam, Kari (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-22)
    <p><i>Background - </i>Spinal stenosis is a clinical diagnosis in which the main symptom is pain radiating to the lower extremities, or neurogenic claudication. Radiological spinal stenosis is commonly observed in the population and it is debated whether patients with no lower extremity pain should be labelled as having spinal stenosis. However, these patients is found in the Norwegian Registry for ...
  • Nanoscopy on-a-chip: super-resolution imaging on the millimeter scale 

    Helle, Øystein Ivar; Coucheron, David Andre; Øie, Cristina Ionica; Ahluwalia, Balpreet Singh (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-04)
    Optical nanoscopy techniques can image intracellular structures with high specificity at sub-diffraction limited resolution, bridging the resolution gap between optical microscopy and electron microscopy. So far conventional nanoscopy lacks the ability to generate high throughput data, as the imaged region is small. Photonic chip-based nanoscopy has demonstrated the potential for imaging large areas, ...
  • Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population 

    Stenesen, Dina B.; Småbrekke, Lars; Olsen, Karina; Grimnes, Guri; Nielsen, Christopher Sivert; Simonsen, Gunnar Skov; Sollid, Johanna U. E.; Furgberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-05)
    <i>Background</i>: Use of hormonal contraceptives has been associated with <i>Staphylococcus aureus</i> nasal carriage in adult women. However, the role of hormonal contraceptives in S. aureus colonization among adolescents and associations with progestin only contraceptives are unknown.<p> <p><i>Methods</i>: We obtained nasal and throat swab samples from 439 girls aged 17–21 years in the ...
  • Indigenous Tourism and the Barents Euro-Arctic Region (BEAR) 

    Olsen, Kjell Ole Kjærland (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
    In this article, it is argued that indigenous tourism must be understood as shaped by European ideas of the Other, as well as a more recent development in global politics. Such broad and increasingly global structures frame those heterogeneous populations that are labeled and label themselves indigenous. Furthermore, the current situation of these peoples is also shaped by their relationships to ...
  • On the Island Sensitivity of Topicalization in Norwegian: An Experimental Investigation 

    Kush, Dave Whitney; Lohndal, Terje; Sprouse, Jonathan (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-03)
    Mainland Scandinavian languages have been reported to allow movement from embedded questions, relative clauses, and complex NPs—domains commonly considered to be islands crosslinguistically. Yet in formal acceptability studies Scandinavian participants often show 'island effects': they reject island-violating movement similarly to native speakers of 'island-sensitive' languages. To investigate this ...
  • Glial activation and inflammation along the Alzheimer's disease continuum 

    Nordengen, Kaja; Kirsebom, Bjørn-Eivind; Henjum, Kristi; Selnes, Per; Gisladottir, Berglind; Wettergreen, Marianne; Torsetnes, Silje Bøen; Grøntvedt, Gøril Rolfseng; Waterloo, Knut; Aarsland, Dag; Nilsson, Lars; Fladby, Tormod (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-21)
    <p><i>Background - </i>Neuronal and glial cell interaction is essential for synaptic homeostasis and may be affected in Alzheimer’s disease (AD). We measured cerebrospinal fluid (CSF) neuronal and glia markers along the AD continuum, to reveal putative protective or harmful stage-dependent patterns of activation. <p><i>Methods - </i>We included healthy controls (<i>n</i> = 36) and Aβ-positive (Aβ+) ...

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