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dc.contributor.authorAndersen, Karoline Kolås
dc.contributor.authorKvarstein, Gunnvald
dc.date.accessioned2022-02-03T08:39:25Z
dc.date.available2022-02-03T08:39:25Z
dc.date.issued2021-10-28
dc.description.abstractObjectives<p> Opioids are the most potent analgesics in the treatment of postoperative pain. Respiratory depression is, however, a serious side effect. The aims of this study were to evaluate current practice and routines for post-operative administration of opioids in a Norwegian university hospital and to evaluate whether the clinical safeguards adequately protected patients’ safety regarding risk of respiratory depression. <p>Methods <p>The study had a retrospective cross-sectional design and included 200 patients, treated with opioids postoperatively. The patients were treated in a post-anesthesia care unit (PACU) before transferal to a surgical ward. Relevant data such as opioid dosages, routes of administration, sedation and respiratory function, routines for patient monitoring, and numbers of patients with opioid induced respiratory depression was collected. <p>Results <p>Two patients (1%) developed respiratory depression that needed naloxone to reverse the effect, and 32 patients (16%) had a respiratory rate (RR) <10/min, which may have been caused by opioids. In the PACU, the patient’s RR was evaluated on a routine base, but after transferal to a surgical ward RR documented in only 7% of the patients. <p>Conclusions<p>The lack of routines for patient monitoring, especially RR, represented a risk of not detecting opioid induced respiratory depression.en_US
dc.identifier.citationAndersen, Kvarstein. Postoperative opioids and risk of respiratory depression - A cross-sectional evaluation of routines for administration and monitoring in a tertiary hospital. Scandinavian Journal of Pain. 2021;21(1):203-207en_US
dc.identifier.cristinIDFRIDAID 1977925
dc.identifier.doi10.1515/sjpain-2020-0060
dc.identifier.issn1877-8860
dc.identifier.issn1877-8879
dc.identifier.urihttps://hdl.handle.net/10037/23910
dc.language.isoengen_US
dc.publisherde Gruyteren_US
dc.relation.journalScandinavian Journal of Pain
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 The Author(s)en_US
dc.titlePostoperative opioids and risk of respiratory depression - A cross-sectional evaluation of routines for administration and monitoring in a tertiary hospitalen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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