dc.contributor.author | Mikkilä, Saija | |
dc.contributor.author | Johansson, Jonas | |
dc.contributor.author | Nordström, Anna Hava | |
dc.contributor.author | Nordström, Peter | |
dc.contributor.author | Emaus, Nina | |
dc.contributor.author | Handegård, Bjørn Helge | |
dc.contributor.author | Morseth, Bente | |
dc.contributor.author | Welde, Boye | |
dc.date.accessioned | 2022-02-10T11:25:25Z | |
dc.date.available | 2022-02-10T11:25:25Z | |
dc.date.issued | 2022-01-26 | |
dc.description.abstract | Aims<p>
The aim was to investigate the long-term association between leisure time physical activity
and hip areal bone mineral density (aBMD), in addition to change in hip aBMD over time, in
32–86 years old women and men.<p>
<p>Methods
<p>Data were retrieved from the 2001, 2007–2008, and 2015–2016 surveys of the Tromsø
Study, a longitudinal population study in Norway. Leisure time physical activity was
assessed by the four-level Saltin-Grimby Physical Activity Level Scale which refers to physical exertion in the past twelve months. Hip aBMD was assessed by Dual-Energy X-ray
Absorptiometry. Linear Mixed Model analysis was used to examine long-term associations
between physical activity and hip aBMD (n = 6324). In addition, the annual change in hip
aBMD was analyzed in a subsample of 3199 participants.<p>
<p>Results
<p>Physical activity was significantly and positively associated with total hip aBMD in the overall
cohort (p<0.005). Participants who reported vigorous activity had 28.20 mg/cm<sup>2</sup> higher
aBMD than those who were inactive (95% CI 14.71; 41.69, controlled for confounders), and
even light physical activity was associated with higher aBMD than inactivity (8.32 mg/cm<sup>2</sup>
,
95% CI 4.89; 11.76). Associations between physical activity and femoral neck aBMD yielded
similar results. Hip aBMD decreased with age in both sexes, although more prominently in
women. From 2001 to 2007–2008, aBMD changed by –5.76 mg/cm<sup>2</sup> per year (95% CI –
6.08; –5.44) in women, and –2.31 mg/cm<sup>2</sup> (95% CI –2.69; –1.93), in men. From 2007–2008
to 2015–2016, the change was –4.45 mg/cm<sup>2</sup> per year (95% CI –4.84; –4.06) in women,
and –1.45 mg/cm<sup>2</sup> (95% CI –1.92; –0.98) in men<p>
<p>Conclusions
<p>In this cohort of adult men and women, physical activity levels were positively associated
with hip aBMD in a dose-response relationship. Hip aBMD decreased with age, although
more pronounced in women than men. | en_US |
dc.identifier.citation | Mikkilä SP, Johansson J, Nordström AH, Nordström P, Emaus N, Handegård BHH, Morseth B, Welde B. A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001-2016. PLOS ONE. 2021 | en_US |
dc.identifier.cristinID | FRIDAID 1973672 | |
dc.identifier.doi | https://doi.org/10.1371/journal.pone.0262228 | |
dc.identifier.issn | 1932-6203 | |
dc.identifier.uri | https://hdl.handle.net/10037/24001 | |
dc.language.iso | eng | en_US |
dc.publisher | Public Library of Science | en_US |
dc.relation.journal | PLOS ONE | |
dc.rights.accessRights | openAccess | en_US |
dc.rights.holder | Copyright 2022 The Author(s) | en_US |
dc.title | A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001-2016 | en_US |
dc.type.version | publishedVersion | en_US |
dc.type | Journal article | en_US |
dc.type | Tidsskriftartikkel | en_US |
dc.type | Peer reviewed | en_US |