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dc.contributor.authorAvenarius, Derk
dc.contributor.authorMüller, Lil-Sofie Ording
dc.contributor.authorRosendahl, Karen
dc.date.accessioned2022-04-28T09:22:38Z
dc.date.available2022-04-28T09:22:38Z
dc.date.issued2015-12-04
dc.description.abstractBackground A large proportion of healthy children have wrist changes on MRI, namely carpal depressions, findings that have been described as pathological in children with juvenile idiopathic arthritis.<p> <p>Objective We performed follow-up imaging in a cohort of healthy children to evaluate carpal surface depressions over time, focusing on the presence of overlying cartilage as a potential discriminator between normal variants and true erosions.<p> <p>Materials and methods 74 of the initial cohort of 89 healthy children (83%) had a re-scan of their wrists using the same protocol, including coronal T1 and fat-saturated T2 sequences. A cartilage-selective sequence was added for this study. We registered number and location of bony depressions and presence of overlying cartilage.<p> <p>Results The total number of carpal depressions increased by age group and over time; their location was unchanged in 370 of 487 (76%) carpal sites and 91 of 117 (78%) metacarpal sites. In total, 426 of the 1,087 (39.2%) bony depressions were covered by cartilage, with a decreasing percentage by age (P=0.001).<p> <p>Conclusion Normal appearances during growth, such as bony depressions, should not be mistaken for pathology. There must be additional findings to support a diagnosis of disease. A cartilage sequence may add to the diagnostic image analysis.en_US
dc.identifier.citationAvenarius D, Müller L-SO, Rosendahl K. Erosion or normal variant? 4-year MRI follow-up of the wrists in healthy children. Pediatric Radiology. 2016;46(3):322-330
dc.identifier.cristinIDFRIDAID 1311228
dc.identifier.doi10.1007/s00247-015-3494-6
dc.identifier.issn0301-0449
dc.identifier.issn1432-1998
dc.identifier.urihttps://hdl.handle.net/10037/24926
dc.language.isoengen_US
dc.publisherSpringeren_US
dc.relation.journalPediatric Radiology
dc.rights.holderCopyright 2015 The Author(s)en_US
dc.titleErosion or normal variant? 4-year MRI follow-up of the wrists in healthy childrenen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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