Show simple item record

dc.contributor.authorvon Brandis, Elisabeth
dc.contributor.authorZadig, Pia Karin Karlsen
dc.contributor.authorAvenarius, Derk Frederik Matthaus
dc.contributor.authorFlatø, Berit
dc.contributor.authorKnudsen, Per Kristian
dc.contributor.authorLilleby, Vibke
dc.contributor.authorNguyen, Bac
dc.contributor.authorRosendahl, Karen
dc.contributor.authorMüller, Lil-Sofie Ording
dc.date.accessioned2022-09-16T07:51:18Z
dc.date.available2022-09-16T07:51:18Z
dc.date.issued2022-06-27
dc.description.abstractObjective - To describe the findings of focal high signal on T2 weighted (T2W) images of the bone marrow in the axial skeleton as assessed by whole-body MRI in healthy and asymptomatic children and adolescents.<p> <p>Material and methods - We assessed the bone marrow of the mandible, shoulder girdle, thorax, spine, and pelvis on water-only Dixon T2W sequences as part of a whole-body MRI protocol in 196 healthy and asymptomatic children aged 5–19 years. Intensity (0–2 scale) and extension (1–4 scale) of focal high signal areas in the bone marrow were scored and divided into minor or major findings, based on intensity and extension to identify the potentially conspicuous lesions in a clinical setting.<p> <p>Results - We registered 415 areas of increased signal in the axial skeleton whereof 75 (38.3%) were major findings. Fifty-eight (29.6%) individuals had at least one major finding, mainly located in the pelvis (54, 72%). We found no differences according to gender. The number of minor findings increased with age (p = 0.020), but there were no significant differences in the number of major findings. The most conspicuous findings were in the pelvis, spine and sternum.<p> <p>Conclusion - Non-specific bone marrow T2W hyperintensities in the axial skeleton are frequently detected on whole-body MRI in healthy, asymptomatic children. Awareness of this is important as some findings may resemble clinically silent lesions in children with suspected multifocal skeletal disease.en_US
dc.identifier.citationvon Brandis, Zadig, Avenarius, Flatø, Knudsen, Lilleby, Nguyen, Rosendahl, Müller. Whole body magnetic resonance imaging in healthy children and adolescents. Bone marrow appearances of the axial skeleton. European Journal of Radiology. 2022;154:1-9en_US
dc.identifier.cristinIDFRIDAID 2043400
dc.identifier.doi10.1016/j.ejrad.2022.110425
dc.identifier.issn0720-048X
dc.identifier.issn1872-7727
dc.identifier.urihttps://hdl.handle.net/10037/26825
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalEuropean Journal of Radiology
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2022 The Author(s)en_US
dc.titleWhole body magnetic resonance imaging in healthy children and adolescents. Bone marrow appearances of the axial skeletonen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


File(s) in this item

Thumbnail

This item appears in the following collection(s)

Show simple item record