Institutt for klinisk medisin: Nye registreringer
Viser treff 401-420 av 1938
-
Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-28)A potential relationship between dysregulation of immune/inflammatory pathways and cognitive impairment has been suggested in severe mental illnesses (SMI), such as schizophrenia (SZ) and bipolar (BD) spectrum disorders. However, multivariate relationships between peripheral inflammatory/immune-related markers and cognitive domains are unclear, and many studies do not account for inter-individual ... -
Bronkiolitt skal ikke behandles med glukokortikoider eller antibiotika
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-30)Vi er inne i en hektisk sesong med virale luftveisinfeksjoner. Respiratorisk syncytialvirus (RS-virus) er den hyppigste årsaken til bronkiolitt hos barn. Pediatriveilederen er tydelig på at perorale glukokortikoider ikke har noen plass i behandlingen av bronkiolitt og at det sjelden er behov for antibiotika. -
Return to Work after Surgery for Cervical Radiculopathy: A Nationwide Registry-based Observational Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-15)Study Design - An observational multicenter study.<p> <p>Summary of Background Data - Return to work (RTW) is increasingly used to assess the standard, benefit, and quality of health care.<p> <p>Objective - The aim of this study was to evaluate sick leave patterns among patients undergoing surgery for cervical radiculopathy and identify predictors of successful RTW using two nationwide ... -
Reflections on the nature of measurement in language-based automated assessments of patients' mental state and cognitive function
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-22)Modern advances in computational language processing methods have enabled new approaches to the measurement of mental processes. However, the field has primarily focused on model accuracy in predicting performance on a task or a diagnostic category. Instead the field should be more focused on determining which computational analyses align best with the targeted neurocognitive/psychological functions ... -
Health characteristics associated with chemsex among men who have sex with men: Results from a cross-sectional clinic survey in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-05)Background Chemsex typically involves drugs such as GHB/GBL, crystal meth and mephedrone, and is increasingly common among MSM. The behaviour has been found to be associated with sexually transmitted infections (STIs) and mental health problems. We aimed to assess the extent of chemsex engagement and associations with different aspects of health, among MSM attending a free specialist walk-in clinic ... -
The use of light, restrictive feeding, fibrous feed and stocking density and the consequences for animal welfare for poultry species kept in Norway - Scientific Opinion of the Panel on Animal Health and Welfare of the Norwegian Scientific Committee for Food and Environment
(Research report; Forskningsrapport, 2022-06-15) -
Joint effect of myocardial infarction and obesity on the risk of venous thromboembolism: The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-19)Background: Myocardial infarction (MI) is associated with an increased risk of venous thromboembolism (VTE). Obesity is a recognized risk factor for both MI and VTE. Whether obesity further increases the risk of VTE in MI patients is scarcely investigated.<p> <p>Aim: To study the joint effect of MI and obesity on the risk of VTE. <p>Methods: Study participants (n = 29 410) were recruited from ... -
The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022)<p><b> Background: </b>Venous thromboembolism (VTE) is associated with increased risk of disability pension. How socioeconomic status (SES) impacts the risk of disability pension after a VTE is unknown. The aim of this nationwide population based cohort study to investigate the interaction between SES and incident VTE on the risk of subsequent disability pension. <p><b> Methods:</b> Using Danish ... -
Do Sexually Abstinent Women have more pelvic floor Disorders?A cross sectional, population based study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-22)Introduction and hypothesis: The aims were to establish the prevalence of sexually abstinent women because of Pelvic Floor Disorders (PFDs) in parous women, and to examine if abstinence was associated with symptoms of PFDs or functional anatomy of the pelvic floor. Methods: Cross-sectional study of parous women responding to a questionnaire and undergoing pelvic floor examination. Distress for ... -
Shortened Palliative Radiotherapy Results in a Lower Rate of Treatment During the Last Month of Life
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-25)Introduction Palliative radiotherapy (PRT) during the last month of life (PRT30) should be avoided because relevant clinical benefits are unlikely to occur. While traditional short-course fractionation regimens are suitable for most patients, a minority may derive gains from higher doses of PRT. Compared to older regimens such as 13 fractions of 3 Gy, more hypofractionated, non-ablative concepts ... -
Markers of extracellular matrix remodeling and systemic inflammation in patients with heritable thoracic aortic diseases
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-20)Background: In approximately 20% of patients with thoracic aortic aneurysms or dissections a heritable thoracic aortic disease (HTAD) is suspected. Several monogenic connective tissue diseases imply high risk of aortic disease, including both non-syndromic and syndromic forms. There are some studies assessing inflammation and extracellular matrix remodeling in patients with non-hereditary aortic ... -
Surgery for degenerative cervical myelopathy in patients with rheumatoid arthritis and ankylosing spondylitis: a nationwide registry-based study with patient-reported outcomes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-15)Purpose To compare patient-reported outcomes (PROMs) following surgery for degenerative cervical myelopathy (DCM) among patients with rheumatoid arthritis (RA) or ankylosing spondylitis (AS) versus those without rheumatic diseases. Methods Data were obtained from the Norwegian Registry for Spine Surgery. The primary outcome was change in the Neck Disability Index (NDI) at 1 year. Secondary endpoints ... -
Reproductive changes among women in their 40s: A cross-sectional study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-05)Introduction The aim was to describe and compare changes in the reproductive pattern of women in their 40s observed over a decade in Scandinavia. Material and Methods Cross-sectional study using the total population of women aged 40–49 years between 2008–2018 in Denmark, Norway and Sweden (on average n = 1.5 million). Aggregated data concerning birth and induced abortion rate were collected and ... -
The impact of implementing patient-reported measures in routine maternity care: a systematic review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-05)Introduction While there is growing interest in applying patient-reported measures (PRMs) in clinical routine, limited collective evidence of the impact of PRMs hinder their widespread use in specific contexts, such as maternity care. Our objective was to synthesize existing emperical evidence on the impact of implementing PRMs in routine maternity care. Material and methods We followed the ... -
External Validation of the Graded Prognostic Assessment in Patients with Brain Metastases from Small Cell Lung Cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-29)Background: Recently, graded prognostic assessment (GPA) for small cell lung cancer (SCLC) patients with brain metastases has been developed. This includes age, performance status, number of brain metastases and presence of extracranial metastases. The aim of the present study was to validate this four-tiered prognostic score in a European cohort of patients. Methods: The retrospective validation ... -
Epidemiology and natural history in 101 subjects with FKRP-related limb-girdle muscular dystrophy R9. The Norwegian LGMDR9 cohort study (2020)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-25)We aimed to investigate the epidemiology and natural history of FKRP-related limb-girdle muscular dystrophy R9 (LGMDR9) in Norway. We identified 153 genetically confirmed subjects making the overall prevalence 2.84/100,000, the highest reported figure worldwide. Of the 153 subjects, 134 (88 %) were homozygous for FKRP c.826C>A giving a carrier frequency for this variant of 1/101 in Norway. Clinical ... -
Magnetic resonance imaging for non-invasive measurement of plastic ingestion in marine wildlife
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)Monitoring plastic ingestion by marine wildlife is important for both characterizing the extent of plastic pollution in the environment and understanding its effect on species and ecosystems. Current methods to detect plastic in the digestive system of animals are slow and invasive, such that the number of animals that can be screened is limited. In this article, magnetic resonance imaging (MRI) ... -
Symptoms of Depression, Anxiety, and Posttraumatic Stress among Patients with Cardiac Pacemakers
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-15)Despite being a prerequisite for tailoring specific therapeutic interventions, knowledge of pattern and prevalence of clinically significant psychiatric symptomatology among patients with cardiac pacemakers (PMs), especially of symptoms of posttraumatic stress, is limited. We studied symptoms of depression, anxiety, and posttraumatic stress among PM patients (PM due to syncope or presyncope) ... -
Management of Orofacial Manifestations of Juvenile Idiopathic Arthritis: Interdisciplinary Consensus-Based Recommendations
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-30)Involvement of the temporomandibular joint (TMJ) is common in juvenile idiopathic arthritis (JIA). TMJ arthritis can lead to orofacial symptoms, orofacial dysfunction, and dentofacial deformity with negative impact on quality of life. Management involves interdisciplinary collaboration. No current recommendations exist to guide clinical management. We undertook this study to develop consensus-based ... -
Decompressive hemicraniectomy for space-occupying brain infarction: Nationwide population-based registry study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-14)Objective: We analyzed data from the Norwegian Stroke Registry (NSR) to study access to and outcomes of decompressive hemicraniectomy for brain infarction in a nationwide routine clinical setting. We also discretionary assessed whether the outcomes were comparable with those achieved in randomized controlled trials (RCTs), and whether the use was in accordance with guidelines. Methods: The NSR ...