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dc.contributor.authorFeng, Yue
dc.contributor.authorReinstein, Dan Z.
dc.contributor.authorNitter, Tore
dc.contributor.authorArcher, Timothy J.
dc.contributor.authorMcAlinden, Colm
dc.contributor.authorBertelsen, Geir
dc.contributor.authorStojanovic, Aleksandar
dc.date.accessioned2023-12-12T08:59:49Z
dc.date.available2023-12-12T08:59:49Z
dc.date.issued2023-07-01
dc.description.abstractPURPOSE:To assess repeatability and agreement of corneal epithelial thickness mapping in eyes with keratoconus using three optical coherence tomography (OCT) devices featuring different technologies: spectral-domain (SD) OCT combined with Placido disk corneal topography (MS-39), swept-source OCT (Anterion), and SD-OCT (Avanti).<p> <p>METHODS:Three consecutive measurements were acquired with the three devices in 60 eyes with keratoconus. The mean epithelial thickness was calculated in the central 2-mm zone and in 2- to 5-mm and 5- to 7-mm diameter rings. The repeatability was calculated using pooled within-subject standard deviation (Sw). The agreement was assessed by paired t tests and Bland-Altman plots. <p>RESULTS:The repeatability (Sw) of the epithelial thickness for the central 2-mm zone was 0.91, 0.71, and 0.93 μm for the MS-39, Anterion, and Avanti, respectively. All thicknesses with the MS-39 were greater than those of the Anterion and Avanti, with mean differences of 4.11 ± 1.34 μm (P < .001) and 0.52 ± 1.30 μm (P = .003), respectively. The 95% limits of agreement were 1.484 to 6.736 μm for the MS-39 and Anterion, −3.068 to 2.028 μm for the Avanti and MS-39, and 1.258 to 5.922 μm for for the Avanti and Anterion. <p>CONCLUSIONS:Epithelial thickness mapping results were most repeatable with the Anterion, followed by the MS-39 and Avanti. The MS-39 gave the thickest values, followed by the Avanti and Anterion. The differences were significant, making the devices not interchangeable for epithelial thickness mapping in eyes with keratoconus.en_US
dc.identifier.citationFeng, Reinstein, Nitter, Archer, McAlinden, Bertelsen, Stojanovic. Epithelial Thickness Mapping in Keratoconic Corneas: Repeatability and Agreement Between CSO MS-39, Heidelberg Anterion, and Optovue Avanti OCT Devices. Journal of refractive surgery. 2023;39(7):474-480en_US
dc.identifier.cristinIDFRIDAID 2177377
dc.identifier.doi10.3928/1081597X-20230606-01
dc.identifier.issn1081-597X
dc.identifier.issn1938-2391
dc.identifier.urihttps://hdl.handle.net/10037/32021
dc.language.isoengen_US
dc.publisherSlacken_US
dc.relation.journalJournal of refractive surgery
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0en_US
dc.rightsAttribution-NonCommercial 4.0 International (CC BY-NC 4.0)en_US
dc.titleEpithelial Thickness Mapping in Keratoconic Corneas: Repeatability and Agreement Between CSO MS-39, Heidelberg Anterion, and Optovue Avanti OCT Devicesen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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