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dc.contributor.advisorIngebrigtsen, Tor
dc.contributor.authorIversen, Mathilde Vea
dc.description.abstractBackground: Studies of aneurysmal subarachnoid hemorrhage (aSAH) report an association between higher patient volumes and better outcomes. In regions with dispersed settlement, this must be balanced against the advantages with shorter pre-hospital transport times and timely access. The aim of this study is to report outcome for unselected aSAH-cases from a well-defined rural population treated in a low-volume neurosurgical center. Methods: This is a retrospective population-based observational cohort study from northern Norway (population 486,450). The University Hospital of North Norway (UNN) provides the only neurosurgical service. We retrieved data for all aSAH cases (n = 332) admitted during 2007 through 2019 from an institution specific register. The outcome measures were mortality rates and functional status assessed with the modified Rankin Scale (mRS). Results: The mean annual number of cases was 26 (range 16-38) and the mean crude incidence rate 5.4 per 100,000 person-years. 279/332 (84 %) cases underwent aneurysm repair, 158 (47.5 %) with endovascular techniques and 121 (36.4 %) with microsurgical clipping, while 53 (15.9 %) did not. The overall mortality rate was 16.0 % at discharge and 23.8 % at 12 months. The proportion with a favorable outcome (mRS scores 0-2) was 36.1 % at discharge and 51.5 % at 12 months. In subgroup analysis of cases who underwent aneurysm repair, the mortality rate was of 4.7 % at discharge and 11.8 % at 12 months, and the proportion with a favorable outcome 42.3 % at discharge and 59.9 % at 12 months. Conclusions: We report satisfactory outcomes after treatment of aSAH in a low-volume neurosurgical department serving a rural population. This indicates a reasonable balance between timely access to treatment and hospital case volume.en_US
dc.descriptionThis Masters thesis is the manuscript version of the published paper that is available in Munin at <a href=></a>.en_US
dc.publisherUiT Norges arktiske universiteten_US
dc.publisherUiT The Arctic University of Norwayen_US
dc.rights.holderCopyright 2023 The Author(s)
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)en_US
dc.subjectAneurysmal subarachnoid hemorrhageen_US
dc.subjectTreatment outcomeen_US
dc.subjectModified Rankin Scaleen_US
dc.titleOutcome of aneurysmal subarachnoid hemorrhage in a population-based cohort: Retrospective registry studyen_US
dc.typeMaster thesisen_US

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Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)