dc.contributor.author | Foscari, Aurelio Giovanni | |
dc.contributor.author | Herzke, Dorte | |
dc.contributor.author | Mowafi, Riham | |
dc.contributor.author | Seiwert, Bettina | |
dc.contributor.author | De Witte, Bavo | |
dc.contributor.author | Delbare, Daan | |
dc.contributor.author | Heras, Gustavo Blanco | |
dc.contributor.author | Gago, Jesus | |
dc.contributor.author | Reemtsma, Thorsten | |
dc.date.accessioned | 2025-07-07T11:35:30Z | |
dc.date.available | 2025-07-07T11:35:30Z | |
dc.date.issued | 2025-06-20 | |
dc.description.abstract | Little is known about the exposure of aquatic biota to tire and road wear particles (TRWP) washed away from roads. Mussels were exposed for 7 days to model TRWP (m-TRWP), produced by milling tire tread particles with pure sand, and analyzed for 21 tire-related compounds by liquid chromatography-high resolution-mass spectrometry (LC-HRMS). Upon exposure to 0.5 g/L of m-TRWP, 15 compounds were determined from 944 μg/kg wet weight (diphenylguanidine, DPG) over 18 μg/kg for an oxidation product of N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6-PPDQ) to 0.6 μg/kg (4-hydroxydiphenyl amine). Transfer into mussels was highest for PTPD, DTPD and 6-PPDQ and orders of magnitude lower for 6-PPD. During 7 days depuration the concentration of all determined chemicals decreased to remaining concentrations between ~50 % (PTPD, DTPD) and 6 % (6-PPD). Suspect and non-target screening found 37 additional transformation products (TPs) of tire additives, many of which did not decrease in concentration during depuration, among them ten likely TPs of DPG, two of 6-PPD and PTPD and two of 1,2-dihydro-2,2,4-trimethylquinoline. A wide variety of chemicals is taken up by mussels upon exposure to m-TRWP and a wide range of TPs is formed, enabling the differentiation of biomarkers of exposure to TRWP and biomarkers of exposure to tire-associated chemicals. | en_US |
dc.identifier.citation | Foscari, Herzke, Mowafi, Seiwert, De Witte, Delbare, Heras, Gago, Reemtsma. Uptake of chemicals from tire wear particles into aquatic organisms - search for biomarkers of exposure in blue mussels. Marine Pollution Bulletin. 2025;219 | en_US |
dc.identifier.cristinID | FRIDAID 2390940 | |
dc.identifier.doi | 10.1016/j.marpolbul.2025.118311 | |
dc.identifier.issn | 0025-326X | |
dc.identifier.issn | 1879-3363 | |
dc.identifier.uri | https://hdl.handle.net/10037/37447 | |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier | en_US |
dc.relation.journal | Marine Pollution Bulletin | |
dc.rights.accessRights | openAccess | en_US |
dc.rights.holder | Copyright 2025 The Author(s) | en_US |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | en_US |
dc.rights | Attribution 4.0 International (CC BY 4.0) | en_US |
dc.title | Uptake of chemicals from tire wear particles into aquatic organisms - search for biomarkers of exposure in blue mussels | en_US |
dc.type.version | publishedVersion | en_US |
dc.type | Journal article | en_US |
dc.type | Tidsskriftartikkel | en_US |
dc.type | Peer reviewed | en_US |