Viser treff 2093-2112 av 10125

    • Detection of quebec polyomavirus dna in samples from different patient groups 

      Prezioso, Carla; Van Ghelue, Marijke; Pietropaolo, Valeria; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-18)
      Polyomaviruses infect many species, including humans. So far, 15 polyomaviruses have been described in humans, but it remains to be established whether all of these are genuine human polyomaviruses. The most recent polyomavirus to be detected in a person is Quebec polyomavirus (QPyV), which was identified in a metagenomic analysis of a stool sample from an 85-year-old hospitalized man. We used PCR ...
    • Detection of tissue factor in platelets: why is it so troublesome? 

      Østerud, Bjarne; Bouchard, Beth A (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-30)
      Tissue factor (TF) is the most important trigger for the extrinsic coagulation pathway. TF, earlier denoted as thromboplastin, has always been a mystery since its discovery due to its abundant presence in most human tissues but not blood. The latter has been extensively studied in a vast quest for possible sources of blood-borne TF yielding many conflicting findings and confusing conclusions regarding ...
    • Detection of xerostomia, Sicca, and Sjogren’s syndromes in a national sample of adults 

      Stankeviciene, Indre; Puriene, Alina; Mieliauskaite, Diana; Stangvaltaite-Mouhat, Lina; Aleksejuniene, Jolanta (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-27)
      Objectives - To assess the prevalence and determinants of xerostomia among adults and identify how many of the ones experiencing xerostomia have Sicca and Sjogren's syndromes.<p> <p>Materials and methods - This cross-sectional study included 1405 35–74-year-old Lithuanians (51.7% response rate) from the five largest Lithuanian cities and 10 peri-urban and rural areas that were randomly selected ...
    • Deteksjon av HER2-reseptor ved tumor mamma med FISH imprint 

      Njøs, Hallvard (Master thesis; Mastergradsoppgave, 2008-09-15)
      Bakgrunn. 20-30% av pasienter med cancer mamma har overuttrykk av HER2 reseptoren (Human Epidermal growth factor Receptor) på overflaten av tumorcellene. HER2-postiv cancer mamma er assosiert med økt tumorvekst, økt metastasering og dårligere prognose. Immunhistokjemi (IHC) og FISH (Fluorescence in situ hybridization) på formalinfiksert parafin innstøpt (FFPE) materiale er de mest brukte metodene ...
    • Deteksjon av lungekreft med spiral-CT og "pet-scan" 

      Varsi, Liv Inger (Master thesis; Mastergradsoppgave, 2007-10-01)
      Introduksjon Lungekreft er et stort helse- og samfunnsmessig problem i den vestlige verden. Lungekreft i sene stadier gir betydelige plager med blant annet dyspnø og smerter. De terapeutiske virkemidler man kan tilby i dag, har liten suksess i å behandle metastatisk sykdom. I Norge er den totale dødelighet på nesten 90 %. Det finnes få effektive diagnostiske verktøy for tidlig oppdaging av lungekreft. ...
    • Determinants for participation in The Norwegian Breast Cancer Screening Programme 

      Lillegaard, Siri Marlen Nordeng (Master thesis; Mastergradsoppgave, 2017-06-20)
      Background: Breast cancer is the most frequent cancer among women worldwide, and the second most important cause of cancer death in developed countries after lung cancer. Early detection with mammographic screening reduces breast cancer mortality. Few studies have investigated factors associated with participation in The Norwegian Breast Cancer Screening Programme. Objective: To identify determinants ...
    • Determinants of blood acylcarnitine concentrations in healthy individuals of the European Prospective Investigation into Cancer and Nutrition 

      Wedekind, Roland; Rothwell, Joseph A.; Viallon, Vivian; Keski-Rahkonen, Pekka; Schmidt, Julie A.; Chajes, Veronique; Katzke, Vna; Johnson, Theron; Santucci de Magistris, Maria; Krogh, Vittorio; Amiano, Pilar; Sacerdote, Carlotta; Redondo-Sánchez, Daniel; Huerta, José María; Tjønneland, Anne; Pokharel, Pratik; Jakszyn, Paula; Tumino, Rosario; Ardanaz, Eva; Sandanger, Torkjel M; Winkvist, Anna; Hultdin, Johan; Schulze, Matthias B.; Weiderpass, Elisabete; Gunter, Marc J.; Huybrechts, Inge; Scalbert, Augustin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-08)
      Background & aims: Circulating levels of acylcarnitines (ACs) have been associated with the risk of various diseases such as cancer and type 2 diabetes. Diet and lifestyle factors have been shown to influence AC concentrations but a better understanding of their biological, lifestyle and metabolic determinants is needed. <p><p>Methods: Circulating ACs were measured in blood by targeted (15 ACs) and ...
    • Determinants of cardiovascular and all-cause mortality in northwest Russia : a 10-year follow-up study 

      Sidorenkov, Oleg; Nilssen, Odd-Ragnar (Journal article; Tidsskriftartikkel, 2012)
      Abstract PURPOSE: To study conventional and novel risk factors associated with high cardiovascular disease (CVD) and all-cause mortality in Russia. METHODS: A prospective cohort study of 3704 adults was performed in Arkhangelsk. The baseline examination was conducted in 1999-2000. The average follow-up was 10.2 years. Information on lifestyle and marital, educational, and psychosocial status was ...
    • Determinants of caregiver satisfaction with child neurodevelopmental assessment in neuropaediatric clinics 

      Kjærandsen, Katarina; Brøndbo, Per Håkan; Halvorsen, Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-12)
      Background - In addition to patient evaluations, caregiver evaluations and experiences are important indicators of the quality of health services. The aim of this study was to examine determinants of caregiver satisfaction with and perceived benefit of child neurodevelopmental assessment in neuropaediatric clinics.<p> <p>Methods - The study was conducted among caregivers of children and adolescents ...
    • Determinants of long-term weight change among middle-aged Swedish women 

      El Reda, Darline; Ström, Peter; Sandin, Sven; Oh, Jin-Kyoung; Adami, Hans Olov; Löf, Marie; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01-07)
      Objective:<br> To describe the determinants of 12‐year weight change among middle‐aged women in Sweden. <br>Methods:<br> In 1991/1992, 49,259 women across Sweden were recruited into a cohort. In 2003, 34,402 (73%) completed follow‐up. Lifestyle and health characteristics including weight were collected, and 12‐year weight change and substantial weight gain (≥+5.0 kg) were calculated; association ...
    • Determinants of non- response to a second assessment of lifestyle factors and body weight in the EPIC-PANACEA study 

      May, Anne M.; Adema, Lotte E.; Romaguera, Dora; Vergnaud, Anne-Claire; Agudo, Antonio; Ekelund, Ulf; Steffen, Annika; Orfanos, Philippos; Slimani, Nadia; Rinaldi, Sabina; Mouw, Traci; Rohrmann, Sabine; Hermann, Silke; Boeing, Heiner; Bergmann, Manuela M.; Jakobsen, Marianne Uhre; Overvad, Kim; Wareham, Nicholas J.; Gonzalez, Carlos; Tjonneland, Anne; Halkjaer, Jytte; Key, Timothy J.; Spencer, Elizabeth A.; Hellström, Veronica; Manjer, Jonas; Hedblad, Bo; Lund, Eiliv; Braaten, Tonje; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie Christine; Rodriguez, Laudina; Sanchez, Maria Jose; Dorronsoro, Miren; Barricarte, Aurelio; Huerta, Jose Maria; Naska, Androniki; Trichopoulou, Antonia; Palli, Domenico; Pala, Valeria; Norat, Teresa; Mattiello, Amalia; Tumino, Rosario; van der Daphne, A.; Bueno-de-Mesquita, H. Bas; Riboli, Elio; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      This paper discusses whether baseline demographic, socio-economic, health variables, length of follow-up and method of contacting the participants predict non-response to the invitation for a second assessment of lifestyle factors and body weight in the European multi-center EPIC-PANACEA study. Over 500.000 participants from several centers in ten European countries recruited between 1992 and 2000 ...
    • Determinants of Staphylococcus aureus Colonization and Infection. “Exploring the Role of Cell Wall Anchored Proteins in Adhesion and Immune Evasion” 

      Ajayi, Clement (Doctoral thesis; Doktorgradsavhandling, 2018-11-09)
      Staphylococcus aureus is an efficient human colonizer and pathogen. S.aureus' ability to colonize and/or cause infections in humans is due to its expression of many virulence factors. These virulence factors aid the bacterium in adhering, invading and evading the host´s immune defences. This study focused on exploring the role of two cell wall anchored proteins: Serine-aspartate containing protein ...
    • Determinants of Staphylococcus aureus colonization and infection: Characterization of interaction between serine-aspartate containing protein D and human Siglec11 and Siglec16 

      Spahiu, Ira (Master thesis; Mastergradsoppgave, 2021-10-15)
      <p><i>Staphylococcus aureus</i> is a Gram-positive opportunistic pathogen responsible for a range of infections that can lead to fatal invasive diseases such as pneumonia or osteomyelitis. Approximately 30% of the healthy adult population are persistently colonized by <i>S. aureus</i> strains in their anterior nares. The molecular mechanism underlying <i>S. aureus</i> colonization and infection ...
    • Determinants of trabecular bone score and prevalent vertebral fractures in women with fragility fractures: a cross-sectional sub-study of NoFRACT 

      Borgen, Tove Tveitan; Bjørnerem, Åshild; Solberg, Lene Bergendal; Andreasen, Camilla; Brunborg, C.; Stenbro, May-Britt; Hübschle, Lars Michael; Figved, Wender; Apalset, Ellen Margrete; Gjertsen, Jan Erik; Basso, Trude; Lund, Ida; Hansen, Ann Kristin; Stutzer, Jens-Meinhard; Dahl, Cecilie; Nordsletten, Lars; Frihagen, Frede; Eriksen, Erik Fink (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-21)
      <i>Summary</i> - Determinants of trabecular bone score (TBS) and vertebral fractures assessed semiquantitatively (SQ1–SQ3) were studied in 496 women with fragility fractures. TBS was associated with age, parental hip fracture, alcohol intake and BMD, not SQ1–SQ3 fractures. SQ1–SQ3 fractures were associated with age, prior fractures, and lumbar spine BMD, but not TBS.<p><p> <i>Introduction</i> ...
    • Determination of copy number and circularization ratio of Tn916-Tn1545 family of conjugative transposons in oral streptococci by droplet digital PCR 

      Lunde, Tracy Munthali; Al-Haroni, Mohammed; Roberts, Adam P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-06)
      <p><I>Background</I>: Tn916 and Tn1545 are paradigms of a large family of related, broad host range, conjugative transposons that are widely distributed in bacteria and contribute to the spread of antibiotic resistance genes (ARGs). Variation in the copy number (CN) of Tn916-Tn1545 elements and the circularization ratio (CR) may play an important role in propagation of ARGs carried by these ...
    • Determination of Cysteine Connectivity in Bioactive Peptides 

      Moen, Merete Kveli (Master thesis; Mastergradsoppgave, 2014-05-20)
      Conotoxins are diverse and well-studied, and is therefore suited as a model to develop a general method for analyzing disulfide-rich peptides. To investigate the folding of both commercially available and self-synthesized Conotoxins, an UHPLC-MS/MS method was developed where one disulfide-bridge was reduced at the time and alkylated with different maleimides. The results from the UHPLC-MS/MS method ...
    • Determination of the binding mode for the cyclopentapeptide CXCR4 antagonist FC131 using a dual approach of ligand modifications and receptor mutagenesis 

      Thiele, Stefanie; Mungalpara, Jignesh; Steen, A.; Rosenkilde, Mette M.; Våbenø, Jon (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Determining the safety and effectiveness of Tai Chi: a critical overview of 210 systematic reviews of controlled clinical trials 

      Yang, Guo-Yan; Hunter, Jennifer; Bu, Fan-Long; Hao, Wen-Li; Zhang, Han; Wayne, Peter M.; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-03)
      Background - This overview summarizes the best available systematic review (SR) evidence on the health effects of Tai Chi.<p> <p>Methods - Nine databases (PubMed, Cochrane Library, EMBASE, Medline, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database (VIP), Sino-Med, and Wanfang Database) were searched for SRs of controlled clinical trials of Tai Chi ...
    • Developement of mucoadhesive polymer-coated liposomes for hydration of the oral mucosa 

      Saleh, Rebwar Salar Nori (Master thesis; Mastergradsoppgave, 2013-05-18)
      Dry mucus in the oral cavity is uncomfortable for patients and can lead to other additional illnesses. Reduced or absence of saliva secretion, caused by the diseases, side effects of drugs, aging, or radiotherapy, can result in issues related to xerostomia and dental health. A system that could contribute to increased hydration of the mucus would reduce the discomfort for the patient. In addition, ...
    • Developing a Linear Mixed Model to Predict RPE and sRPE in Female Elite Football Players Using External Load Measures 

      Vollstad, Jakob Kjos (Master thesis; Mastergradsoppgave, 2023-05-15)
      Abstract Introduction: Despite the broad consensus on the importance of training load monitoring and management for footballers’ performance, existing research on female football players remains scarce. The present study aimed to develop and evaluate a linear mixed model (LMM) to predict the rating of perceived exertion (RPE) and session RPE (sRPE) in female elite football players using GPS-derived ...