Viser treff 4492-4511 av 10096

    • Identifying anti-TNF response biomarkers in ulcerative colitis using a diffusion-based signalling model 

      Singh, Amrinder; Anderssen, Endre; Fenton, Christopher Graham; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-18)
      <p><i>Motivation:</i> Resistance to anti-TNF therapy in subgroups of ulcerative colitis (UC) patients is a major challenge and incurs significant treatment costs. Identification of patients at risk of nonresponse to anti-TNF is of major clinical importance. To date, no quantitative computational framework exists to develop a complex biomarker for the prognosis of UC treatment. Modelling patient-wise ...
    • Identifying decisions in optometry: A validation study of the decision identification and classification taxonomy for use in medicine (DICTUM) in optometric consultations 

      Sundling, Vibeke; Stene, Hege Anita; Eide, Hilde; Ofstad, Eirik Hugaas (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-18)
      <i>Objective</i> - The aim of this study was to assess the validity and reliability of the Decision Identification and Classification Taxonomy for Use in Medicine (DICTUM) applied to optometry, to compare decisions in medical and optometric consultations, and to describe decisions in optometry. <p> <p><i>Methods</i> - The study had a cross-sectional design. Data was collected from January to ...
    • Identifying eating habits in Finnish children: A cross-sectional study 

      De Oliveira Figueiredo, Rejane Augusta; Viljakainen, Jannina; Viljakainen, Heli; Roos, Eva; Rounge, Trine Ballestad; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-15)
      <p><i>Background - </i>We aimed to identify different eating habits among Finnish children and to evaluate their association with meal patterns, breakfast consumption, and socio-demographic characteristics in a large, nationwide cohort of children. <p><i>Methods - </i>We evaluated 10,569 children aged 9–14 years into the Finnish Health in Teens cohort in a cross-sectional design. The hierarchical ...
    • Identifying Measures Used for Assessing Quality of YouTube Videos with Patient Health Information: A Review of Current Literature 

      Gabarron, Elia; Fernandez-Luque, Luis; Armayones, Manuel; Lau, Annie YS (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Recent publications on YouTube have advocated its potential for patient education. However, a reliable description of what could be considered quality information for patient education on YouTube is missing. Objective: To identify topics associated with the concept of quality information for patient education on YouTube in the scientific literature. Methods: A literature review was ...
    • Identifying predictive signalling networks for Vedolizumab response in ulcerative colitis. 

      Singh, A.; Fenton, Christopher Graham; Anderssen, Endre; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-11)
      Background - In ulcerative colitis (UC), the molecular mechanisms that drive disease development and patient response to therapy are not well understood. A significant proportion of patients with UC fail to respond adequately to biologic therapy. Therefore, there is an unmet need for biomarkers that can predict patients’ responsiveness to the available UC therapies as well as ascertain the most ...
    • Identifying Resilience Factors of Distress and Paranoia During the COVID-19 Outbreak in Five Countries 

      Mækelæ, Martin Jensen; Reggev, Niv; Defelipe, Renata P.; Dutra, Natalia; Tamayo, Ricardo; Klevjer, Kristoffer; Pfuhl, Gerit (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-10)
      The ongoing COVID-19 pandemic outbreak has affected all countries with more than 100 million confirmed cases and over 2.1 million casualties by the end of January 2021 worldwide. A prolonged pandemic can harm global levels of optimism, regularity, and sense of meaning and belonging, yielding adverse effects on individuals' mental health as represented by worry, paranoia, and distress. Here we studied ...
    • Identifying sequence variants contributing to hereditary breast and ovarian cancer in BRCA1 and BRCA2 negative breast and ovarian cancer patients 

      Jarhelle, Elisabeth; Stensland, Hilde Monica Frostad Riise; Hansen, Geir Åsmund Myge; Skarsfjord, Siri; Jonsrud, Christoffer; Ingebrigtsen, Monica; Strømsvik, Nina; Van Ghelue, Marijke (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-27)
      Families with breast and ovarian cancer are often tested for disease associated sequence variants in <i>BRCA1</i> and <i>BRCA2</i>. Pathogenic sequence variants (PVs) in these two genes are known to increase breast and ovarian cancer risks in females. However, in most families no PVs are detected in these two genes. Currently, several studies have identified other genes involved in hereditary breast ...
    • Identifying signaling pathway responsible for SRC-3 serine 857 phosphorylation. A study in lung cancer cells 

      Kaur, Gurjit (Master thesis; Mastergradsoppgave, 2014-05-20)
      Signal transduction mediated by protein kinases and phosphatases is complex and highly coordinated. The mitogen activated protein kinases (MAPKs) are key components that transduce extracellular stimuli to biological responses by a three-tier module. The biological functions of steroid receptor coactivator-3 (SRC-3), a coactivator of nuclear hormone receptors and numerous transcription factors, is ...
    • Identifying Staphylococcus haemolyticus surface proteins. Development of a novel method for detection of bacterial surface proteins expressed during colonisation of human keratinocytes 

      Wolden, Runa (Master thesis; Mastergradsoppgave, 2018-05-15)
      The aim was to develop a method for identification of expressed surface proteins of Staphylococcus haemolyticus when colonising human keratinocytes. S. haemolyticus and HaCaT cells were grown together and separated with FACS prior to surface protein shaving using the LPI™FlowCell technology (Nanoxis Consulting AB). TMT-tags were used to investigate up- and downregulation of proteins comparing S. ...
    • Identifying the drivers of multidrug-resistant Klebsiella pneumoniae at a European level 

      Kachalov, Viacheslav N.; Nguyen, Huyen; Balakrishna, Suraj; Salazar-Vizcaya, Luisa; Sommerstein, Rami; Kuster, Stefan P.; Hauser, Anthony; Abel-Zur Wiesch Genannt Hülsho, Pia Karoline; Klein, E; Kouyos, Roger D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-29)
      Beta-lactam- and in particular carbapenem-resistant Enterobacteriaceae represent a major public health threat. Despite strong variation of resistance across geographical settings, there is limited understanding of the underlying drivers. To assess these drivers, we developed a transmission model of cephalosporin- and carbapenem-resistant <i>Klebsiella pneumoniae</i>. The model is parameterized using ...
    • Identitetsdribling i samisk fotball. En kvalitativ studie av samisk selvforståelse i samisk idrett 

      Sandberg, Odd Inge (Master thesis; Mastergradsoppgave, 2018-05-21)
      I denne masteroppgaven har jeg sett på hvilke måter samiske identitetskonstruksjoner utrykkes, bekreftetes og forhandles i samiske idrettskonkurranser blant utøverne. Jeg har videre sett på hvordan ulike samiske markører for samisk identitet bidrar til å styrke og utfordre idrettsutøvernes selvidentiet. Forskningen er gjennomført som en kvalitativ studie med intervjuer av fem mannlige fotballspillere ...
    • Identitetsstatus i forhold til angst og kontrollplassering : to meta-analyser 

      Lillevoll, Kjersti Rønningen (Master thesis; Mastergradsoppgave, 2007-11-01)
      Marcias identitetsstatusparadigme har vært en dominerende tilnærming i identitetsforskningen. Rundt 1100 studier har brukt modellen for å undersøke ulike dimensjoner av identitetsutviklingen, men ingen systematisk meta-analyse har vært utført. Hensikten med denne studien var å utføre to meta-analyser på identitetsstatus i forhold til angst (studie 1), og kontrollplassering (locus of control) (studie ...
    • Identitetsstatus i relasjon til selvfølelse og autoritarianisme : to meta-analytiske studier 

      Ryeng, Marianne S. (Master thesis; Mastergradsoppgave, 2007-11)
      Målet med denne oppgaven var å undersøke sammenhengen mellom Marcias (1966) identitetsstatusparadigme og variablene selvfølelse (Studie 1) og autoritarianisme (Studie 2), ved hjelp av meta-analytisk metode. Følgende databaser ble benyttet for å identifisere relevante studier mellom 1966 og 2005: PsycINFO, ERIC, Sociological Abstracts, og Dissertation Abstracts International. Utvalget til Studie 1 ...
    • Identity construction in medical student stories about experiences of disgust in early nursing home placements: A dialogical narrative analysis 

      Warmington, Sally; Johansen, May-Lill; Wilson, Hamish (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-17)
      Objectives To explore medical students’ reflective essays about encounters with residents during preclinical nursing home placements.<p> <p>Design Dialogical narrative analysis aiming at how students characterise residents and construct identities in relation to them. <p>Setting Medical students’ professional identity construction through storytelling has been demonstrated in contexts including ...
    • Identity construction of Sami people with disabilities 

      Melbøe, Line (Journal article; Tidsskriftartikkel; Peer reviewed, 2018)
      The aim of this article is to explore how the political, technological and economic development of recent decades has influenced the identity construction of Sami people with disabilities. While Sami identity work is described as a continuous process carried out in everyday life, the subject is addressed through a presentation and discussion of three narratives. The analysis demonstrates how different ...
    • Identity-supportive nursing of patients with dementia in nursing homes 

      Drageset, Ingrid Marie Saga; Normann, Hans Ketil; Elstad, Ingunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03)
      This article aims to explore how nursing can support a sense of continuity and identity in patients with advanced dementia disease, living in nursing homes. Fourteen carers and managers in two nursing homes in northern Norway were interviewed. The analysis and discussion are based on the theoretical concepts of identity, continuity and person-centred nursing. This study concludes that an awareness ...
    • Idrett som integrasjonsarena - Betydninger av idrettsdeltagelse blant mannlige flyktninger 

      Corneliussen, Alexander Juhl (Master thesis; Mastergradsoppgave, 2021-05-19)
      Hensikten med studien er å undersøke hvilken betydning idrettsdeltagelse har hatt for integrering av mannlige flyktninger. For å undersøke idrettsdeltagelsens betydning for integrering tar studien for seg tre forskningsspørsmål: • Hvordan beskriver flyktningene sine møter med den organiserte idretten? • Hvilke betydninger har idrettsdeltagelse for integrering? • Hva slags betydning tillegger ...
    • "If you do not birget [manage] then you don't belong here": a qualitative focus group study on the cultural meanings of suicide among Indigenous Sámi in arctic Norway 

      Stoor, Jon Petter Anders; Berntsen, Gro; Hjelmeland, Heidi Marie; Silviken, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-24)
      Suicide is a major public health issue across the Arctic, especially among Indigenous Peoples. The aim of this study was to explore and describe cultural meanings of suicide among Sámi in Norway. Five open-ended focus group discussions (FGDs) were conducted with 22 Sámi (20) and non-Sámi (2) participants in South, Lule, Marka, coastal and North Sámi communities in Norway. FGDs were recorded, transcribed ...
    • IgE-mediated peanut allergy: Current and novel predictive biomarkers for clinical phenotypes using multi-omics approaches 

      Czolk, Rebecca; Klueber, Julia; Sørensen, Martin; Wilmes, Paul; Codreanu-Morel, Françoise; Skov, Per Stahl; Hilger, Christiane; Bindslev-Jensen, Carsten; Ollert, Markus; Kuehn, Annette (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-28)
      Food allergy is a collective term for several immune-mediated responses to food. IgE-mediated food allergy is the best-known subtype. The patients present with a marked diversity of clinical profiles including symptomatic manifestations, threshold reactivity and reaction kinetics. In-vitro predictors of these clinical phenotypes are evasive and considered as knowledge gaps in food allergy diagnosis ...
    • Ignorance or awareness of changes measured in a probabilistic inference task 

      Kreis, Isabel Viola; Tjelmeland, Håkon; Biegler, Robert; Tröbinger, Luzia Rosa; Pfuhl, Gerit (Conference object; Konferansebidrag, 2017)
      A cognitive bias often reported for schizophrenia is the tendency to make decisions based on little evidence, namely the jumping to conclusions (JTC) bias. The beads task (Huq et al., 1988) is the most commonly used task to investigate the JTC and different attempts were made to explain the JTC. One proposition is that patients might miscomprehend the task and assume volatility, i.e. a change of ...