Now showing items 625-644 of 5517

    • Can oxytocin augmentation modify the risk of epidural analgesia by maternal age in cesarean sections? 

      Rossen, Janne; Klungsøyr, Kari; Albrechtsen, Susanne; Løkkegård, Ellen; Rasmussen, Steen; Bergholt, Thomas; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-07)
      <p><i>Introduction</i>: Maternal age is an established risk factor for cesarean section; epidural analgesia and oxytocin augmentation may modify this association. We investigated the effects and interactions of oxytocin augmentation, epidural analgesia and maternal age on the risk of cesarean section.</p> <p><i>Material and methods</i>: In all, 416 386 nulliparous women with spontaneous onset of ...
    • Can structural indicators explain gender difference in life expectancy (LE) at birth among WHO member countries? 

      Bye, Stefan (Master thesis; Mastergradsoppgave, 2012-06)
      Forskjellen i life expectancy at birth mellom kjønn varierer fra land til land og i de fleste tilfellene så lever kvinner lengre enn menn. Det globale gjennomsnittet er på ca 7% lengre levetid for kvinner enn menn, men man har forskjeller som er helt opp i 23%. Det finnes etablerte hypoteser på hvorfor kvinner lever lengre enn menn og i denne oppgaven vil jeg se på hvordan sosiale og strukturelle ...
    • Can the health related quality of life measure QOLIBRI- overall scale (OS) be of use after stroke? A validation study 

      Heiberg, Guri Anita; Pedersen, Synne Garder; Friborg, Oddgeir; Nielsen, Jørgen Feldbæk; Holm, Henriette Stabel; von Steinbüchel, Nicole; Arntzen, Cathrine; Anke, Audny (Journal article; Tidsskriftartikkel; Peer reviewed, 2018)
      <i><p>Background</i>: Brief measures of health-related quality of life (HRQOL) that assess both patient-reported functioning and well-being after stroke are scarce. The objective of this study was to examine reliability and validity of one of these measures, the patient-reported Quality of Life after Brain Injury–Overall Scale (QOLIBRI-OS), in patients after stroke.</p> <i><p>Methods</i>: Stroke ...
    • Can video mobile phones improve CPR quality when used for dispatcher assistance during simulated cardiac arrest? 

      Bolle, Stein Roald; Gilbert, Mads; Scholl, Jeremiah (Journal article; Tidsskriftartikkel; Peer reviewed, 2009)
      Background: Because mobile telephones may support video calls, emergency medical dispatchers may now connect visually with bystanders during pre-hospital cardiopulmonary resuscitation (CPR). We studied the quality of simulated dispatcher-assisted CPR when guidance was delivered to rescuers by video calls or audio calls from mobile phones. Methods: One hundred and eighty high school students were ...
    • Can vitamin D-3 supplementation prevent bone loss in persons with MS? A placebo-controlled trial 

      Steffensen, Linn Hofsøy; Jørgensen, Lone; Straume, Bjørn; Mellgren, Svein Ivar; Kampman, Margitta Theodora (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Multiple sclerosis (MS) is a possible cause of secondary osteoporosis. In this phase II trial we assessed whether a weekly dose of 20,000 IU vitamin D3 prevents bone loss in ambulatory persons with MS age 18–50 years. ClinicalTrials.gov ID NCT00785473. All patients managed at the University Hospital of North Norway who fulfilled the main inclusion criteria were invited to participate in this ...
    • Can vitamin D3 supplementation prevent bone loss in persons with MS? 

      Steffensen, Linn Hofsøy (Doctoral thesis; Doktorgradsavhandling, 2012-12-13)
      In persons with Multiple sclerosis (MS) low bone mineral density (BMD) is more prevalent when compared with healthy controls and MS may be a possible cause of secondary osteoporosis. BMD is primarily determined by genetic and hormonal factors, body mass index, physical activity and intake of calcium and vitamin D. Vitamin D level at 50 nmol/L or higher is classified as sufficient, however, optimal ...
    • Can we rely on simulated patients' satisfaction with their consultation for assessing medical students' communication skills? A cross-sectional study 

      Gude, Tore; Grimstad, Hilde; Holen, Are; Anvik, Tor; Baerheim, Anders; Fasmer, Ole Bernt; Hjortdahl, Per; Vaglum, Per Jørgen Wiggen (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-18)
      Background: In medical education, teaching methods offering intensive practice without high utilization of faculty resources are needed. We investigated whether simulated patients’ (SPs’) satisfaction with a consultation could predict professional observers’ assessment of young doctors’ communication skills. <p>Methods: This was a comparative cross-sectional study of 62 videotaped consultations ...
    • Cancer and venous thromboembolism 

      Jensvoll, Hilde (Doctoral thesis; Doktorgradsavhandling, 2015-10-02)
      Venøs tromboembolisme (VTE) er et samlebegrep for lungeemboli og dyp venetrombose. VTE rammer ofte kreftpasienter og representerer en ledende dødsårsak i denne pasient gruppen. Dette understreker viktigheten av å kartlegge risikofaktorer for kreft-relatert VTE for å muliggjøre forebyggende behandling hos pasienter med høy risiko. En VTE hendelse kan også være det første symptomet på en bakenforliggende ...
    • Cancer associated fibroblasts in stage I-IIIA NSCLC: Prognostic impact and their correlations with tumor molecular markers 

      Kilvær, Thomas Karsten; Rakaeekhanehkenari, Mehrdad; Hellevik, Turid; Al-Saad, Samer; Paulsen, Erna-Elise; Busund, Lill-Tove; Dønnem, Tom; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-07)
      Background Cancer Associated Fibroblasts (CAFs) are thought to regulate tumor growth and metastasis. Fibroblast Activating Protein 1 (FAP-1) is a marker for fibroblast activation and by many recognized as the main marker of CAFs. Alpha Smooth Muscle Actin (α-SMA) is a general myofibroblast marker, and can be used to identify CAFs. This study investigates the prognostic impact of FAP-1 and α-SMA ...
    • Cancer cervicis uteri i Sub-Sahara Afrika : en litteraturstudie 

      Hana, Johan (Master thesis; Mastergradsoppgave, 2011-09-15)
      Insidensen av livmorhalskreft i regionen er blant verdens høyeste. Kontinentet er hardt rammet av HIV/AIDS, og da denne sykdommen medfører smitte av andre og flere typer onkogene HPV, samt raskere progresjon av dysplasi, vanskeliggjør dette arbeidet med å få ned nye krefttilfeller. Videre viser studier generelt manglende kunnskap om livmorhalskreft i befolkningen, også blant velutdannende og urbane ...
    • Cancer incidence and mortality in Chukotka, 1997–2010 

      Dudarev, AA; Chupakhin, Valery; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Objectives. The general aim was to assess cancer incidence and mortality among the general population of Chukotka in 1997 2010 and to compare it with the population of Russia. Methods. Cancer data were abstracted from the annual statistical reports of the P.A. Hertzen Research Institute of Oncology in Moscow. The annual number and percent of cases, crude and age-standardized cancer incidence ...
    • Cancer incidence in Arkhangelskaja Oblast in northwestern Russia. The Arkhangelsk Cancer Registry 

      Lebedintseva, Jelena A.; Vaktskjold, Arild; Lund, Eiliv; Korotov, Dmitrij S.; Tkatsjov, Anatolij V.; Podjakova, Tatjana S. (Journal article; Tidsskriftartikkel; Peer reviewed, 2005-07-19)
      Background: Data concerning incidence and prevalence of cancer in the different regions of Russia have traditionally not been provided on a basis that facilitated comparison with data from countries in western parts of Europe. The oncological hospital in Arkhangelsk, in co-operation with Universitetet i Tromsø (Norway), has established a population based cancer registry for Arkhangelskaja Oblast ...
    • The cancer may come back: experiencing and managing worries of relapse in a North Norwegian village after treatment 

      Skowronski, Magdalena; Risør, Mette Bech; Andersen, Rikke Sand; Foss, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-18)
      Little is known about how people living in the aftermath of cancer treatment experience and manage worries about possible signs of cancer relapse, not as an individual enterprise but as socially embedded management. One-year ethnographic fieldwork was conducted in a coastal village of under 3000 inhabitants in northern Norway. Ten villagers who had undergone cancer treatment from six months to five ...
    • Cancer mortality in the indigenous population of coastal Chukotka, 1961–1990 

      Dudarev, Alexy A.; Chupakhin, Valery; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Objectives. The general aim was to assess the pattern and trend in cancer mortality among the indigenous people of coastal Chukotka during the period 1961 1990. Methods. All cases of cancer deaths of indigenous residents of the Chukotsky district in the northeasternmost coast of Chukotka Autonomous Okrug were copied from personal death certificates. There were a total of 219 cancer deaths during ...
    • Cancer therapy-induced oral mucositis in head and neck cancer patients 

      Gussgard, Anne Margrete (Doctoral thesis; Doktorgradsavhandling, 2015-06-17)
      Background: Radiotherapy causes oral mucositis (OM) that is painful and disrupts eating, talking, social activities and general health. OM may even interrupt cancer therapy. Any intervention that can reduce OM will lead to improvement in treatment and quality of life for patients. It is essential to have a suitable tool to measure potentially effective and new treatments against OM. Objective: To ...
    • Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reduced 

      Hellevik, Turid; Pettersen, ingvild; Berg, Vivian; Winberg, Jan-Olof; Moe, Bjørn Torvald Greve; Bartnes, Kristian; Paulssen, Ruth H; Busund, Lill-Tove; Bremnes, Roy M.; Chalmers, Antony; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      BACKGROUND: Cancer-Associated Fibroblasts (CAFs) are significant components of solid malignancies and play central roles in cancer sustainability, invasion and metastasis. In this study we have investigated the invasive capacity and matrix remodelling properties of human lung CAFs after exposure to ablative doses of ionizing radiation (AIR), equivalent to single fractions delivered by stereotactic ...
    • Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation 

      Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-12)
      Accumulating evidence supports the notion that high-dose (>5 Gy) radiotherapy (RT) regimens are triggering stronger pro-immunogenic effects than standard low-dose (2 Gy) regimens. However, the effects of RT on certain immunoregulatory elements in tumors remain unexplored. In this study, we have investigated the effects of high-dose radiotherapy (HD-RT) on the immunomodulating functions of cancer-associated ...
    • Cancer-related venous thromboembolism: epidemiology and risk factors 

      Blix, Kristine (Doctoral thesis; Doktorgradsavhandling, 2014-11-28)
      The association between cancer and venous thromboembolism (VTE) was described already in the 19th century and cancer has later been acknowledged as one of the most important risk factors for VTE. Population-based studies on the subject with information about confounders and validated endpoints are lacking. The first aim of this thesis was to estimate the frequency of VTE among cancer patients in a ...
    • Cannabinoid therapy for Epilepsy : A literature review and a survey among neuro-paediatricians 

      Mosulet, George Vladimir (Master thesis; Mastergradsoppgave, 2018-06-04)
      Abstract Background: The aim for this thesis has been to investigate the use of cannabinoids in treatment of epilepsy. The topic is currently under a lot of discussion in many countries, and there is a high pressure on the health community to make these substances available from both patients, their families and politicians. This thesis consists of two parts. First, I aimed to review the literature ...
    • Capping carious exposures in adults: a randomized controlled trial investigating mineral trioxide aggregate versus calcium hydroxide 

      Kundzina, Rita; Stangvaltaite, Lina; Eriksen, Harald; Kerosuo, Eero N (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-28)
      Aim:<br> The aim of this multicentre, parallel-group randomized clinical trial was to compare the effectiveness of mineral trioxide aggregate (MTA) and a conventional calcium hydroxide liner (CH) as direct pulp capping materials in adult molars with carious pulpal exposure.<br> Methodology:<br> Seventy adults aged 18–55 years were randomly allocated to two parallel arms: MTA (White ProRoot, ...