<i>Background</i>: Treatment of rheumatic diseases in children often includes long-term needle injections, which represent a risk for refusing medication based on potential needle-fear. How nurses manage children’s fear and pain during the initial educational training session of subcutaneous injections, may affect the management of the subsequent injections in the home settings. The aim of this study ...

Ostensive signals are an integral part of normal everyday communication, a body of evidence indicates that some of them are innately recognizable to infants. The eyebrow flash has been suggested to be an ostensive signal by authors of human ethology studies. This have been shown little attention in the psychological field, this pilot study therefore has as goal of setting the basis for studying young ...

<p><b> Background:</b> Children of parents with a mental illness are at high risk of developing a mental disorder as a result of transgenerational transmission. Without effective intervention, they could form the next generation of psychiatric patients. ChildTalks+ is a preventive intervention involving four structured psychoeducational sessions designed for parents affected by a mental disorder ...

<i>Objective</i>: The existing eligible randomized controlled trials (RCTs) were critically appraised for the effectiveness and safety of Chinese herbal medicine Dengzhan Shenmai for ischemic stroke.<p> <p><i>Design</i>: Systematic review and meta-analysis (CRD42016042914, http://www.crd.york.ac.uk/PROSPERO). Methods: Six electronic databases were searched from inception to May 2016. Risk ratio ...

Chinese herbs are thought to be effective for type A H1N1 influenza. Series of Chinese herbs have been authorized recommended by the Chinese government, and until now a number of clinical trials of Chinese herbs for H1N1 influenza have been conducted. However, there is no critically appraised evidence such as systematic reviews or metaanalyses on potential benefits and harms of medicinal herbs for ...

Extracts of Chinese red yeast rice (RYR, a traditional dietary seasoning of Monascus purpureus) contains several active ingredients including lovastatin, and several trials of its possible lipid-lowering effects have been conducted. This meta-analysis assesses the effectiveness and safety of RYR preparations on lipid modification in primary hyperlipidemia. We included randomized controlled trials ...

Mucoadhesive drug therapy destined for localized drug treatment is gaining increasing importance in today’s drug development. Chitosan, due to its known biodegradability, bioadhesiveness and excellent safety profile offers means to improve mucosal drug therapy. We have used chitosan as mucoadhesive polymer to develop liposomes able to ensure prolonged residence time at vaginal site. Two types of ...

Chronic skin wounds are an exponentially increasing problem on a world basis, and are often hard to treat due to bacterial biofilm formation and resistance to different antibiotic treatments. Antimicrobial photodynamic therapy (aDPT) shows promise in resolving this issue, but clinical based treatments have yet to be established although photodynamic therapy is used for other conditions. A new ...

Due to inappropriate or excessive use of antibiotics, multi resistance has become a global problem which threatens the public health. Photodynamic therapy has emerged as a promising and important approach in many fields of drug therapy. In recent years, many studies on photodynamic therapy for infections have shown promising results. One of the advantages of using PDT in treatment of infections is ...