<i>Background</i> - The EQ-5D is the most widely used generic preference-based health-related quality of life measure. It comprises five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. The usual activities dimension asks respondents to evaluate the severity of problems in their usual activities, such as work, study, housework, family or leisure activities. ...

Background: Optimization of the genetic potential for bone accrual in early life may prevent future fractures. Possible modification factors include lifestyle factors such as nutrition and physical activity. Measured levels of bone mineral density (BMD) and bone mass content (BMC) are indicators of bone strength, and are correlated with fracture risk. This study explored the impact of self-reported ...

The Incredible Years Teacher Classroom Management (IY TCM) programme has shown promise in reducing behaviour problems among high-risk children in childcare. However, at present, we do not know whether the IY TCM successfully improves the child–teacher relationship in childcare and whether the effects manifest in both the population and in high-risk groups. Hence, we conducted a quasi-experimental ...

Introduction: Takotsubo cardiomyopathy (TTC) is a transient left ventricular apical, medial or basal dysfunction, recovering completely without myocardial injury. It was first clinically described in 1991 by Sato et al. Impact of psychological distress and personality factors remains unclear. The aim of the study was to assess if the personality trait of neuroticism, can increase the vulnerability ...

Career development is a lifelong process that starts in infancy and is shaped by a number of different factors during childhood, adolescence, and adulthood. Even though career development is shaped through life, relatively little is known about the predictors of occupational aspirations in childhood. Therefore, in the present work we investigate how the stereotypicality of a mother’s occupation ...

Aims. To evaluate whether reduced waiting time influences survival of patients treated with whole-brain radiotherapy (WBRT) for brainmetastases. Materials and Methods. Retrospective intention-to-treat study including 110 patients treated with primary WBRT (typically 10 fractions of 3Gy; no other treatment between diagnosis and WBRT). Uni- and multivariate tests were performed. Results. Median ...

<i>Background</i> - Dog‐assisted therapy in the dental clinic may be an attractive alternative to sedation for anxious patients. Including a dental therapy dog in a clinical setting introduces new hazards and potential risks to health and safety for both humans and animal.<p> <p><i>Objectives</i> - The study aims to describe potential hazards associated with risks to humans by having a therapy ...

Bacterial biofilms have an impact in medical and industrial environments because they often confer protection to bacteria against harmful agents, and constitute a source from which microorganisms can disperse. Conjugative plasmids can enhance bacterial ability to form biofilms because conjugative pili act as adhesion factors. However, plasmids may interact with each other, either facilitating or ...

Background and purpose: Impulse control disorders (ICDs) are common among Parkinson's disease patients using dopamine agonists. We wanted to determine whether ICD patients have higher dopamine agonist serum concentrations than those without any sign of ICD.<p> <p>Methods: Patients who used either pramipexole or ropinirole depot once daily were screened for ICDs using the validated Questionnaire ...

Human DOR/TP53INP2 displays a unique bifunctional role as a modulator of autophagy and gene transcription. However, the domains or regions of DOR that participate in those functions have not been identified. Here we have performed structure/function analyses of DOR guided by identification of conserved regions in the DOR gene family by phylogenetic reconstructions. We show that DOR is present in ...