• Antimicrobial resistance acquisition via natural transformation: context is everything 

      Winter, Macaulay; Buckling, Angus; Harms, Klaus; Johnsen, Pål Jarle; Vos, Michiel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-26)
      Natural transformation is a process where bacterial cells actively take up free DNA from the environment and recombine it into their genome or reconvert it into extra-chromosomal genetic elements. Although this mechanism is known to mediate the uptake of antibiotic resistance determinants in a range of human pathogens, its importance in the spread of antimicrobial resistance is not always appreciated. ...
    • Testing for the fitness benefits of natural transformation during community-embedded evolution 

      Winter, Macaulay; Harms, Klaus; Johnsen, Pål Jarle; Buckling, Angus; Vos, Michiel (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-01)
      Natural transformation is a process where bacteria actively take up DNA from the environment and recombine it into their genome or reconvert it into extra-chromosomal genetic elements. The evolutionary benefits of transformation are still under debate. One main explanation is that foreign allele and gene uptake facilitates natural selection by increasing genetic variation, analogous to meiotic ...