Pirilä, Emma; Väyrynen, Otto; Sundquist, Elias; Päkkilä, Kaisa; Nyberg, Pia; Nurmenniemi, Sini; Pääkkönen, Virve; Pesonen, Paula; Dayan, Dan; Vered, Marilena; Uhlin-Hansen, Lars; Salo, Tuula (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-26)
Oral tongue squamous cell carcinoma (OTSCC) has a high mortality rate and the incidence
is rising worldwide. Despite advances in treatment, the disease lacks specific prognostic
markers and treatment modality. The spreading of OTSCC is dependent on the tumor microenvironment
and involves tumor-associated macrophages (TAMs). Although the presence
of TAMs is associated with poor prognosis in OTSCC, ...