• External validation of prediction models for pneumonia in primary care patients with lower respiratory tract infection: An individual patient data meta-analysis 

      Schierenberg, Alwin; Minnaard, Margaretha C.; Hopstaken, Rogier M.; Van De Pol, Alma C.; Broekhuizen, Berna D.L.; De Wit, Niek J.; Reitsma, Johannes B.; Van Vugt, Saskia F.; Graffelman, Aleida W.; Melbye, Hasse; Rainer, Timothy H.; Steurer, Johann; Holm, Anette; Gonzales, Ralph; Dinant, Geert-Jan; De Groot, Joris A.H.; Verheij, Theo J.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-26)
      Background:<br> Pneumonia remains difficult to diagnose in primary care. Prediction models based on signs and symptoms (S&S) serve to minimize the diagnostic uncertainty. External validation of these models is essential before implementation into routine practice. In this study all published S&S models for prediction of pneumonia in primary care were externally validated in the individual patient ...