Now showing items 1-7 of 7

    • Gene variations in oestrogen pathways, CYP19A1 , daily 17ß-estradiol and mammographic density phenotypes in premenopausal women. 

      Flote, Vidar Gordon; Furberg, Anne-Sofie; McTiernan, Anne; Frydenberg, Hanne; Ursin, Giske; Iversen, Anita; Lofterød, Trygve; Ellison, Peter T.; Wist, Erik; Egeland, Thore; Wilsgaard, Tom; Makar, Karen W; Chang-Claude, Jenny; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-12-19)
    • Impact of pre-diagnostic triglycerides and HDL-cholesterol on breast cancer recurrence and survival by breast cancer subtypes 

      Lofterød, Trygve; Mortensen, Elin Synnøve; Nalwoga, Hawa; Wilsgaard, Tom; Frydenberg, Hanne; Risberg, Terje; Eggen, Anne Elise; McTiernan, Anne; Aziz, Sura Mohammed; Wist, Erik; Stensvold, Andreas; Reitan, Jon Brinchmann; Akslen, Lars A.; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-15)
      <i>Background</i>: High triglycerides and low levels of high density lipoprotein (HDL)-cholesterol are observed to promote tumor growth. However, whether breast cancer heterogeneity may explain the contradictory influence of triglycerides and cholesterol observed on breast cancer prognosis remains unclear.<p> <p><i>Methods</i>: A population-based survival study among 464 breast cancer cases ...
    • Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer 

      Vaysse, Charlotte; Lømo, Jon; Garred, Øystein; Fjeldheim, Frøydis Nyborg; Lofterød, Trygve; Schlichting, Ellen; McTiernan, Anne; Frydenberg, Hanne; Husøy, Anders; Lundgren, Steinar; Fagerland, Morten W; Richardsen, Elin; Wist, Erik; Muller, Catherine; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-03)
      Growing evidence indicates that adiposity is associated with breast cancer risk and negatively affects breast cancer recurrence and survival, a paracrine role of mammary adipose tissue being very likely in this process. In contrast to other adipose depots, occurrence of a sub-inflammatory state of mammary adipose tissue defined by dying adipocytes surrounded by macrophages forming crown-like structures ...
    • Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer 

      Flote, Vidar Gordon; Vettukattil, Muhammad Riyas; Bathen, Tone Frost; Egeland, Thore; McTiernan, Anne; Frydenberg, Hanne; Husøy, Anders; Finstad, Sissi Espetvedt; Lømo, Jon; Garred, Øystein; Schlichting, Ellen; Wist, Erik; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-08)
      <b>Background:</b> High-Density Lipoprotein (HDL)-cholesterol, has been associated with breast cancer development, but the association is under debate, and whether lipoprotein subfractions is associated with breast tumor characteristics remains unclear.<br> <b>Methods:</b> Among 56 women with newly diagnosed invasive breast cancer stage I/II, aged 35–75 years, pre-surgery overnight fasting serum ...
    • Metabolite and lipoprotein responses and prediction of weight gain during breast cancer treatment 

      Madssen, Torfinn Støve; Thune, Inger; Flote, Vidar Gordon; Lundgren, Steinar; Bertheussen, Gro Falkener; Frydenberg, Hanne; Wist, Erik; Schlichting, Ellen; Schäfer, Hartmut; Fjøsne, Hans Erikssønn; Vettukattil, Muhammad Riyas; Lømo, Jon; Bathen, Tone Frost; Giskeødegård, Guro F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-07)
      <p><i>Background</i>: Breast cancer treatment has metabolic side effects, potentially affecting risk of cardiovascular disease (CVD) and recurrence. We aimed to compare alterations in serum metabolites and lipoproteins during treatment between recipients and non-recipients of chemotherapy, and describe metabolite profiles associated with treatment-related weight gain.</p> <p><i>Methods</i>: This ...
    • Polymorphisms in the estrogen receptor alpha gene (ESR1), daily cycling estrogen and mammographic density phenotypes 

      Fjeldheim, Frøydis Nyborg; Frydenberg, Hanne; Flote, Vidar Gordon; McTiernan, Anne; Furberg, Anne-Sofie; Ellison, Peter T.; Barrett, Emily S.; Wilsgaard, Tom; Jasienska, Grazyna; Ursin, Giske; Wist, Erik; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-07)
      Background: Single nucleotide polymorphisms (SNPs) involved in the estrogen pathway and SNPs in the estrogen receptor alpha gene (ESR1 6q25) have been linked to breast cancer development, and mammographic density is an established breast cancer risk factor. Whether there is an association between daily estradiol levels, SNPs in ESR1 and premenopausal mammographic density phenotypes is unknown. Methods: ...
    • Validation of repeated self-reported n-3 PUFA intake using serum phospholipid fatty acids as a biomarker in breast cancer patients during treatment 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 

      Brunvoll, Sonja Hjellegjerde; Thune, Inger; Frydenberg, Hanne; Flote, Vidar Gordon; Bertheussen, Gro Falkener; Schlichting, Ellen; Bjerve, Kristian S; Hjartåker, Anette (Journal article; Tidsskriftartikkel; Peer reviewed, 2018)
      <p><i>Background</i>: The role of n-3 polyunsaturated fatty acids (PUFAs) in breast cancer is not clear and under debate. To explore this relationship it is important to have proper validated dietary assessment methods for measuring the intake of n-3 PUFAs. The aim of the current study is to validate two different methods used to assess the intake of selected n-3 PUFAs as well as food sources of ...