Blar i forfatter Det helsevitenskapelige fakultet "Nordal, Ellen Berit"

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    • Anti-type II collagen antibodies, anti-CCP, IgA RF and IgM RF are associated with joint damage, assessed eight years after onset of juvenile idiopathic arthritis (JIA) 

      Berntson, Lillemor; Nordal, Ellen Berit; Fasth, Anders; Aalto, Kristiina; Herlin, T; Nielsen, Susan; Rygg, Marite; Zak, M; Ronnelid, J (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Brief Report: The Genetic Profile of Rheumatoid Factor–Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis 

      Hinks, Anne; Marion, Miranda C.; Cobb, Joanna; Comeau, Mary E.; Sudman, Marc; Ainsworth, Hannah C.; Bowes, John; Becker, Mara L.; Bohnsack, John F.; Haas, Johannes-Peter; Lovell, Daniel J.; Mellins, Elizabeth D.; Nelson, J. Lee; Nordal, Ellen Berit; Punaro, Marilynn; Reed, Ann M.; Rose, Carlos D.; Rosenberg, Alan M.; Rygg, Marite; Smith, Samantha L.; Stevens, Anne M.; Videm, Vibeke; Wallace, Carol A.; Wedderburn, Lucy R.; Yarwood, Annie; Yeung, Rae S.M.; Langefeld, Carl D.; Thompson, Susan D.; Thomson, Wendy; Prahalad, Sampath (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-09)
      <i><p>Objective</i>: Juvenile idiopathic arthritis (JIA) comprises 7 heterogeneous categories of chronic childhood arthritides. Approximately 5% of children with JIA have rheumatoid factor (RF)–positive arthritis, which phenotypically resembles adult rheumatoid arthritis (RA). Our objective was to compare and contrast the genetics of RF‐positive polyarticular JIA with those of RA and selected other ...

    • Bronkiolitt skal ikke behandles med glukokortikoider eller antibiotika 

      Nordal, Ellen Berit; Granslo, Hildegunn Norbakken; Esaiassen, Eirin; Leknessund, Carina Benedikte Bjørkvoll; Forsdahl, Bård Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-30)
      Vi er inne i en hektisk sesong med virale luftveisinfeksjoner. Respiratorisk syncytialvirus (RS-virus) er den hyppigste årsaken til bronkiolitt hos barn. Pediatriveilederen er tydelig på at perorale glukokortikoider ikke har noen plass i behandlingen av bronkiolitt og at det sjelden er behov for antibiotika.

    • Changing patterns in treatment, remission status, and categories in a long-term Nordic cohort study of juvenile idiopathic arthritis 

      Glerup, Mia; Arnstad, Ellen Dalen; Rypdal, Veronika; Peltoniemi, Suvi; Aalto, Kristiina; Rygg, Marite; Nielsen, Susan; Fasth, Anders; Berntson, Lillemor; Nordal, Ellen Berit; Herlin, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-10)
      Objective - To explore sustainability of achieved remission off medication and defined International League of Associations for Rheumatology (ILAR) categories in juvenile idiopathic arthritis (JIA) and describe the trajectory of disease course over time by comparing treatment, disease activity, and ILAR categories from baseline, 8 years, and 18 years after disease onset.<p> <p>Methods - A total ...

    • Disease activity and outcome in juvenile idiopathic arthritis - a longitudinal cohort study in the Nordic countries 

      Nordal, Ellen Berit (Doctoral thesis; Doktorgradsavhandling, 2012-05-16)
      SUMMARY This thesis is based on the Nordic juvenile idiopathic arthritis (JIA) cohort study. In a multi-centre population-based setting a prospective followup of juvenile idiopathic arthritis (JIA) was performed. Pediatric rheumatology centers in Denmark, Finland, Norway and Sweden included children with newly diagnosed JIA during a 3.5 year period starting January 1st 1997. The study was focused ...

    • Early self-reported pain in juvenile idiopathic arthritis (JIA) is related to long-term outcomes. Results from the Nordic JIA cohort study. 

      Arnstad, Ellen Dalen; Rypdal, Veronika Gjertsen; Peltoniemi, Suvi; Herlin, T; Berntson, Lillemor; Fasth, Anders; Nielsen, Susan; Glerup, Mia; Ekelund, Maria; Zak, Marek; Aalto, Kristiina; Nordal, Ellen Berit; Romundstad, Pål Richard; Rygg, Marite (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-28)
      <p><i>Objective</i>: To study self‐reported pain early in the disease course of juvenile idiopathic arthritis (JIA) as predictor of long‐term disease outcomes.</p> <p><i>Methods</i>: Consecutive cases of JIA with disease onset 1997‐2000 from defined geographical areas of Norway, Sweden, Finland and Denmark were prospectively enrolled in this population‐based cohort study. Self‐reported, disease‐related ...

    • Fatigue in young adults with juvenile idiopathic arthritis 18 years after disease onset: data from the prospective Nordic JIA cohort 

      Arnstad, Ellen Dalen; Glerup, Mia; Rypdal, Veronika Gjertsen; Peltoniemi, Suvi; Fasth, Anders; Nielsen, Susan; Zak, Marek; Aalto, Kristiina; Berntson, Lillemor; Nordal, Ellen Berit; Herlin, Troels; Romundstad, Pål Richard; Rygg, Marite (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-12)
      Background: To study fatigue in young adults with juvenile idiopathic arthritis (JIA) 18 years after disease onset, and to compare with controls. Methods: Consecutive children with onset of JIA between 1997 and 2000, from geographically defined areas of Norway, Sweden, Denmark and Finland were followed for 18 years in a close to population-based prospective cohort study. Clinical features, ...

    • Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases 

      Hinks, A; Bowes, J; Cobb, J; Ainsworth, HC; Marion, MC; Comeau, ME; Sudman, M; Han, B; Becker, ML; Bohnsack, JF; de Bakker, PIW; Haas, JP; Hazen, M; Lovell, DJ; Nigrovic, PA; Nordal, Ellen Berit; Punnaro, M; Rosenberg, AM; Rygg, Marite; Smith, S.L.; Wise, CA; Videm, Vibeke; Wedderburn, LR; Yarwood, A; Yeung, RSM; Prahalad, S; Langefeld, CD; Raychaudhuri, S; Thompson, SD; Thomson, W (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-20)
      Objectives: Juvenile idiopathic arthritis ( JIA) is a heterogeneous group of diseases, comprising seven categories. Genetic data could potentially be used to help redefine JIA categories and improve the current classification system. The human leucocyte antigen (HLA) region is strongly associated with JIA. Fine-mapping of the region was performed to look for similarities and differences in ...

    • Growing up with chronic arthritis: the confusing matter of classification 

      Nordal, Ellen Berit; Guillaume-Czitrom, Severine; Sibilia, Jean (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-09)
      Disease classification in rheumatology is a matter of debate, in paediatrics between International League Against Rheumatism (ILAR) classification ‘pros and cons’, as well as between paediatric and adult rheumatologists. Indeed, there is no consensus yet about how we should name the disease of adults with juvenile idiopathic arthritis (JIA) in childhood. The non-concordance of adult and paediatric ...

    • HLA-B27 predicts a more extended disease with increasing age at onset in boys with juvenile idiopathic arthritis 

      Nordal, Ellen Berit; Berntson, L.; Damgård, M.; Andersson-Gäre, B.; Herlin, T.; Nielsen, S.; Rygg, M.; Zak, M.; Fasth, A. (Conference object; Konferansebidrag, 2008-09-15)

    • Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant 

      Wang, Qiang; Martínez-Bonet, Marta; Kim, Taehyeung; Sparks, Jeffrey A.; Ishigaki, Kazuyoshi; Chen, Xiaoting; Sudman, Marc; Aguiar, Vitor; Sim, Sangwan; Hernandez, Marcos Chiñas; Chiu, Darren J.; Wactor, Alexandra; Wauford, Brian; Marion, Miranda C.; Gutierrez-Arcelus, Maria; Bowes, John; Eyre, Stephen; Nordal, Ellen Berit; Prahalad, Sampath; Rygg, Marite; Videm, Vibeke; Raychaudhuri, Soumya; Weirauch, Matthew T.; Langefeld, Carl D.; Thompson, Susan D.; Nigrovic, Peter A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-16)
      TRAF1/C5 was among the first loci shown to confer risk for inflammatory arthritis in the absence of an associated coding variant, but its genetic mechanism remains undefined. Using Immunochip data from 3,939 patients with juvenile idiopathic arthritis (JIA) and 14,412 control individuals, we identified 132 plausible common non-coding variants, reduced serially by single-nucleotide polymorphism ...

    • Incidence and predictors of Uveitis in juvenile idiopathic arthritis in a Nordic long-term cohort study. 

      Nordal, Ellen Berit; Rypdal, Veronika Gjertsen; Christoffersen, Terje; Aalto, Kristiina; Berntson, Lillemor; Fasth, Anders; Herlin, Troels; Nielsen, Susan; Peltoniemi, Suvi; Straume, Bjørn; Zak, Marek S.; Rygg, Marite (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-18)
      Background: The incidence of uveitis associated with juvenile idiopathic arthritis (JIA) varies around the world. Our aim was to investigate the incidence and predictors of uveitis in a Nordic population-based cohort. <br>Methods: Consecutive JIA cases from defined geographical areas in Denmark, Finland, Sweden and Norway with disease onset between January 1997 to June 2000 were followed for ...

    • Inflammatory Biomarkers Can Differentiate Acute Lymphoblastic Leukemia with Arthropathy from Juvenile Idiopathic Arthritis Better Than Standard Blood Tests 

      Brix, Ninna; Glerup, Mia; Foell, Dirk; Kessel, Christoph; Wittkowski, Helmut; Berntson, Lillemor; Fasth, Anders; Nielsen, Susan; Nordal, Ellen Berit; Rygg, Marite; Hasle, Henrik; Herlin, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-04)
      Objective - To evaluate the predictive value of biomarkers of inflammation like phagocyte-related S100 proteins and a panel of inflammatory cytokines in order to differentiate the child with acute lymphoblastic leukemia (ALL) from juvenile idiopathic arthritis (JIA).<p> <p>Study design - In this cross-sectional study, we measured S100A9, S100A12, and 14 cytokines in serum from children with ALL ...

    • Long-term outcomes in juvenile idiopathic arthritis: 18 years of follow-up in the population-based Nordic Juvenile Idiopathic Arthritis (JIA) cohort. 

      Glerup, Mia; Rypdal, Veronika Gjertsen; Arnstad, Ellen Dalen; Ekelund, Maria; Peltoniemi, Suvi; Aalto, Kristiina; Rygg, Marite; Toftedal, Peter; Nielsen, Susan; Fasth, Anders; Berntson, Lillemor; Nordal, Ellen Berit; Herlin, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-14)
      <i>Objectives</i> - This study assessed the long‐term course, remission rate and disease burden in juvenile idiopathic arthritis (JIA) 18 years after disease onset in a population‐based setting from the early biologic era.<p><p> <i>Methods</i> - A total of 510 consecutive cases of JIA with disease onset between 1997 and 2000 from defined geographic regions in Denmark, Norway, Sweden and Finland ...

    • Longterm Outcomes of Temporomandibular Joints in Juvenile Idiopathic Arthritis: 17 Years of Followup of a Nordic Juvenile Idiopathic Arthritis Cohort. 

      Glerup, Mia; Stoustrup, Peter Bangsgaard; Matzen, Louise Hauge; Rypdal, Veronika Gjertsen; Nordal, Ellen Berit; Frid, Paula; Arnstad, Ellen Dalen; Rygg, Marite; Thorarensen, Olafur; Ekelund, Maria; Berntson, Lillemor; Fasth, Anders; Nilsson, H; Peltoniemi, Suvi; Aalto, Kristiina; Arte, Sirpa; Toftedal, Peter; Nielsen, Susan; Kreiborg, S.; Herlin, T; Pedersen, T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-01)
      <i>Objective</i> - To determine the prevalence of orofacial symptoms, dysfunctions, and deformities of the temporomandibular joint (TMJ) in juvenile idiopathic arthritis (JIA) 17 years after disease onset.<p> <p><i>Methods</i> - Drawn from a prospective, population-based Nordic JIA cohort with disease onset from 1997 to 2000, 420 consecutive cases were eligible for orofacial evaluation of TMJ ...

    • M-ficolin: a valuable biomarker to identify leukaemia from juvenile idiopathic arthritis 

      Brix, Ninna; Glerup, Mia; Thiel, Steffen; Mistegaard, Clara Elbæk; Skals, Regitze Gyldenholm; Berntson, Lillemor; Fasth, Anders; Nielsen, Susan Mary; Nordal, Ellen Berit; Rygg, Marite; Hasle, Henrik; Albertsen, Birgitte Klug; Herlin, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-22)
      Objective: Distinction on clinical grounds between acute lymphoblastic leukaemia presenting with arthropathy (ALLarthropathy) and juvenile idiopathic arthritis (JIA) is difficult, as the clinical and paraclinical signs of leukaemia may be vague. The primary aim was to examine the use of lectin complement pathway proteins as markers to differentiate ALLarthropathy from JIA. The secondary aims were ...

    • Management of Orofacial Manifestations of Juvenile Idiopathic Arthritis: Interdisciplinary Consensus-Based Recommendations 

      Stoustrup, Peter; Resnick, Cory M.; Abramowicz, Shelly; Pedersen, Thomas K.; Michelotti, Ambra; Küseler, Annelise; Koos, Bernd; Verna, Carlalberta; Nordal, Ellen Berit; Granquist, Eric J.; Halbig, Josefine Mareile; Kristensen, Kasper Dahl; Kaban, Leonard B.; Arvidsson, Linda Zamoline; Spiegel, Lynn; Stoll, Matthew L.; Lerman, Melissa A.; Glerup, Mia; Defabianis, Patrizia; Frid, Paula Hanna Therese; Alstergren, Per; Cron, Randy Q.; Ringold, Sarah; Nørholt, Sven Erik; Peltomaki, Timo; Larheim, Tore Arne; Herlin, Troels; Peacock, Zachary S.; Kellenberger, Christian J.; Twilt, Marinka (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-30)
      Involvement of the temporomandibular joint (TMJ) is common in juvenile idiopathic arthritis (JIA). TMJ arthritis can lead to orofacial symptoms, orofacial dysfunction, and dentofacial deformity with negative impact on quality of life. Management involves interdisciplinary collaboration. No current recommendations exist to guide clinical management. We undertook this study to develop consensus-based ...

    • May antihistone antibodies replace antinuclear antibodies (ANA) as a predictor of uveitis in Juvenile idiopathic arthritis? 

      Songstad, Nils Thomas; Nordal, Ellen Berit; Berntson, L.; Straume, Bjørn; Rygg, M. (Conference object; Konferansebidrag, 2008-09-15)

    • The Norwegian version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR) 

      Flatø, Berit; Rygg, Marite; Nordal, Ellen Berit; Røisland, Mona; Ødegård, Hanne Beate; Hoftun, Gry Børmark; Songstad, Nils Thomas; Consolaro, Alessandro; Bovis, Francesca; Ruperto, Nicolino (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-07)
      The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient-reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patient versions of the JAMAR in the Norwegian language. The reading comprehension of ...

    • A novel serum calprotectin (MRP8/14) particle-enhanced immuno-turbidimetric assay (sCAL turbo) helps to differentiate systemic juvenile idiopathic arthritis from other diseases in routine clinical laboratory settings 

      Foell, Dirk; Saers, Melanie; Park, Carolin; Brix, Ninna; Glerup, Mia; Kessel, Christoph; Wittkowski, Helmut; Hinze, Claas; Berntson, Lillemor; Fasth, Anders; Myrup, Charlotte; Nordal, Ellen Berit; Rygg, Marite; Hasle, Henrik; Albertsen, Birgitte Klug; Herlin, Troels; Holzinger, Dirk; Niederberger, Christian; Schlüter, Bernhard (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-25)
      Background Differential diagnosis in children with signs of unprovoked inflammation can be challenging. In particular, differentiating systemic juvenile idiopathic arthritis (SJIA) from other diagnoses is difficult. We have recently validated the complex of myeloid-related proteins 8/14 (MRP8/14, also known as S100A8/A9 complex or serum calprotectin) as a helpful biomarker supporting the diagnosis ...