• FKBP8 and the autophagy-inducing Class-III PI3K Complex Roles of LIR dependent interactions 

      Bhujabal, Zambarlal (Doctoral thesis; Doktorgradsavhandling, 2017-09-22)
      Autophagy (Greek meaning “self eating”) is a renovation process in cells. Dysfunctional autophagy plays a major role in human diseases including cancer, inflammatory and neurodegenerative diseases. Misfolded or aggregated proteins, damaged organelles, such as mitochondria, endoplasmic reticulum and peroxisomes, as well as intracellular pathogens are degraded by autophagy. During the process, the ...