Blar i forfatter Doktorgradsavhandlinger (Helsefak) "Hald, Øyvind Holsbø"
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Molecular aspects of high-risk neuroblastoma and novel therapeutic opportunities
Hald, Øyvind Holsbø (Doctoral thesis; Doktorgradsavhandling, 2020-05-29)Neuroblastoma is a highly heterogenous cancer of childhood. High-risk disease has a poor prognosis with survival around 50% and cured patients suffer treatment related late effects. Better therapy is needed. Increased knowledge of the molecular biology of high-risk neuroblastomas is essential to devise new treatments. High-risk neuroblastomas are frequently MYCN-amplified (MNA). MNA is correlated ...