• Role of Laeverin in the pathophysiology of preeclampsia 

      Nystad, Mona (Doctoral thesis; Doktorgradsavhandling, 2018-05-11)
      Preeclampsia is a pregnancy-specific disease, affecting 5-10% of human pregnancies worldwide. It is defined as new-onset hypertension after 20 weeks of gestation with either proteinuria and/or organ failure. Laeverin is a membrane-bound aminopeptidase exclusively expressed in the placenta. Our previous studies revealed a significant upregulation of laeverin mRNA in preeclamptic placentas, building ...