Blar i forfatter Doktorgradsavhandlinger (Helsefak) "Schniers, Armin"
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The proteome of ulcerative colitis - Functional analyses of the active disease and the remission state in comparison with healthy controls
Schniers, Armin (Doctoral thesis; Doktorgradsavhandling, 2019-06-18)This work characterizes the proteome of human colon mucosa in ulcerative colitis (UC). We developed an optimized sample preparation method of colon mucosa biopsies for bottom-up proteomics and applied it to characterize the proteomes of active UC, remission from UC, and healthy controls. Abundances of proteins related to the immune system and to protein processing in the endoplasmic reticulum ...