<i>Background</i> - The number of nonagenarian cancer patients (≥ 90 years) is continuously increasing, and radiotherapy is performed in a relevant proportion of patients, as surgery and chemotherapy are often not feasible for these patients. However, the evidence regarding the feasibility and treatment outcomes after radiotherapy for this patient group is very limited.<p> <p><i>Methods</i> - All ...

A key driver to offering smart services is an infrastructure of Cyber-Physical systems (CPS)s. By definition, CPSs are intertwined physical and computational components that integrate physical behaviour with computation. The reason is to autonomously execute a task or a set of tasks providing a service or a list of end-users services. In real-life applications, CPSs operate in dynamically changing ...

Introduction - Obesity is one of the main threats to public health in western countries and increases the risk of several diseases, overall morbidity and mortality. Sustained weight loss will reduce risk factors and improve several obesity comorbidities. Options are conservative treatment such as lifestyle changes, bariatric surgery or medications. Conservative treatment has a low success rate, and ...

A detailed, well-dated record of pollen and sedimentary ancient DNA (sedaDNA) for the period 15 000–9500 cal a bp describes changes at Lake Bolshoye Shchuchye in the Polar Ural Mountains, located far east of the classical Lateglacial sites in western Europe. Arctic tundra rapidly changed to lusher vegetation, possibly including both dwarf (Betula nana) and tree birch (B. pubescens), dated in our ...

Intensive study of the Greenland Ice Sheet's (GrIS) subglacial drainage has been motivated by its importance for ice dynamics and for nutrient/sediment export to coastal ecosystems. This has revealed consistent seasonal development of efficient subglacial drainage in the lower ablation area. While some hydrological models show qualitative agreement with field data, conflicting evidence (both field- ...

Free-base <i>meso</i>-triarylcorroles have been found to undergo oxidative coupling with an excess of pyrrole in dichloromethane in the presence of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) affording 5/10-pyrrole-appended isocorroles in reasonable yields (35–60%) and in a matter of seconds. The free-base isocorrole ligands could all be complexed to copper with Cu(OAc)₂·H₂O ...

The fish species vendace (<i>Coregonus albula</i>) invaded the sub‐arctic Pasvik watercourse during the second half of the 1980s, and became the dominant pelagic species in the upstream part of the watercourse within a few years. Life history traits of the pioneer population of vendace in Pasvik were recorded from 1991–2000. A rapid increase in population density in the upstream part of the watercourse ...

Background - While regular physical activity is associated with reduced mortality and morbidity in general populations, health outcomes and functional capacity related to upholding strenuous endurance exercise beyond the age of 65 years are only sparsely studied. The aim of this study is to assess associations of prolonged strenuous endurance sport practice with ageing, functional decline, morbidity ...